Search Results - "Yang, Jiehong"
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A critical review of Astragalus polysaccharides: From therapeutic mechanisms to pharmaceutics
Published in Biomedicine & pharmacotherapy (01-03-2022)“…As the important active ingredients of Astragali Radix (AR), Astragalus polysaccharides (APs) have therapeutic potential for multiple diseases including…”
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Formononetin protects against inflammation associated with cerebral ischemia-reperfusion injury in rats by targeting the JAK2/STAT3 signaling pathway
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Formononetin is a type of phytoestrogen obtained from the Chinese medical herb Red Clover. It exhibits anti-neoplastic hepatoprotective, and neuroprotective…”
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Protective effects of Astragaloside IV against oxidative injury and apoptosis in cultured astrocytes by regulating Nrf2/JNK signaling
Published in Experimental brain research (01-06-2021)“…Ischemic stroke is a worldwide complex brain disease that results in numerous disabilities and deaths. It leads to the deprivation of oxygen and glucose, which…”
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Green and Efficient Ultrasonic-Assisted Extraction of Bioactive Components from Salvia miltiorrhiza by Natural Deep Eutectic Solvents
Published in Molecules (Basel, Switzerland) (29-12-2019)“…Natural deep eutectic solvents (NaDESs) are recently developed green solvent alternatives to conventional fossil solvents. The present work systematically…”
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Ultrasound-assisted preparation of ‘Ready-to-use’ extracts from Radix Paeoniae Rubra with natural deep eutectic solvents and neuroprotectivity evaluation of the extracts against cerebral ischemic/ reperfusion injury
Published in Ultrasonics sonochemistry (01-03-2022)“…[Display omitted] •A ready-to-use NaDES extract of RPR was screened out of 27 NaDESs.•The extraction yields of ChCl-Sor was higher than conventional…”
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Danhong injection alleviates cerebral ischemia/reperfusion injury by improving intracellular energy metabolism coupling in the ischemic penumbra
Published in Biomedicine & pharmacotherapy (01-08-2021)“…Danhong injection (DHI) is a compound Chinese medicine widely used in China for treatment of ischemic cardio-cerebrovascular diseases. However, limited data…”
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Screening, Optimization, and Bioavailability Research of Natural Deep Eutectic Solvent Extracts from Radix Pueraria
Published in Molecules (Basel, Switzerland) (31-01-2021)“…Natural deep eutectic solvent (NaDES) is generally considered as a greener alternative to fossil solvent, with great potential in various areas. In the present…”
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Combination of Radix Astragali and Safflower Promotes Angiogenesis in Rats with Ischemic Stroke via Silencing PTGS2
Published in International journal of molecular sciences (21-01-2023)“…Promotion of angiogenesis and restoration of the blood flow in the ischemic penumbra is an effective treatment for patients with ischemic stroke (IS). Radix…”
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Danhong injection alleviates cerebral ischemia-reperfusion injury by inhibiting mitochondria-dependent apoptosis pathway and improving mitochondrial function in hyperlipidemia rats
Published in Biomedicine & pharmacotherapy (01-01-2023)“…Cerebral ischemia threatens human health and life. Hyperlipidemia is a risk of cerebral ischemia. Danhong injection (DHI) is a traditional Chinese medical…”
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Network Analysis and Experimental Verification of the Mechanisms of Hydroxysafflor Yellow A in Ischemic Stroke Following Atherosclerosis
Published in Molecules (Basel, Switzerland) (28-11-2023)“…Hydroxysafflor yellow A (HSYA) is derived from L. (Honghua in Chinese) and is used to treat cardiovascular and cerebrovascular disease. However, the mechanism…”
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Pharmacokinetic-pharmacodynamic modeling analysis for hydroxysafflor yellow A-calycosin in compatibility in normal and cerebral ischemic rats: A comparative study
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Astragalus and Safflower are commonly used in the treatment of stroke. Studies have shown that their two active components, hydroxysafflor yellow A (HSYA) and…”
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Network Pharmacology and Molecular Docking-Based Mechanism Study to Reveal the Protective Effect of Salvianolic Acid C in a Rat Model of Ischemic Stroke
Published in Frontiers in pharmacology (27-01-2022)“…Salvianolic acid C (SAC) is a major bioactive component of (Danshen), a Chinese herb for treating ischemic stroke (IS). However, the mechanism by which SAC…”
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Therapeutic effect of Yinhuapinggan granules mediated through the intestinal flora in mice infected with the H1N1 influenza virus
Published in Frontiers in microbiology (29-04-2024)“…In this study, we examined the therapeutic effects of Yinhuapinggan granules (YHPGs) in influenza-infected mice. We also examined how YHPGs affect the…”
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Hydroxysafflor Yellow A and Anhydrosafflor Yellow B Protect Against Cerebral Ischemia/Reperfusion Injury by Attenuating Oxidative Stress and Apoptosis via the Silent Information Regulator 1 Signaling Pathway
Published in Frontiers in pharmacology (30-09-2021)“…Hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB) are the main water-soluble compounds in Carthamus tinctorius L. However, studies on the…”
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Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1 signaling pathway
Published in Biomedicine & pharmacotherapy (01-08-2024)“…To explore the neuroprotective mechanism of artemisinin against ischemic stroke from the perspective of NLRP3-mediated pyroptosis. Serum metabolomics…”
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Polydatin prevent lung epithelial cell from Carbapenem-resistant Klebsiella pneumoniae injury by inhibiting biofilm formation and oxidative stress
Published in Scientific reports (18-10-2023)“…Abstract Carbapenem-resistant Klebsiella pneumoniae (CRKP) causes severe inflammation in various infectious diseases, such as bloodstream infections,…”
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Optimization of Extraction or Purification Process of Multiple Components from Natural Products: Entropy Weight Method Combined with Plackett-Burman Design and Central Composite Design
Published in Molecules (Basel, Switzerland) (14-09-2021)“…In this paper, the optimization of the extraction/purification process of multiple components was performed by the entropy weight method (EWM) combined with…”
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Post-Ischemic Stroke Cardiovascular Risk Prevention and Management
Published in Healthcare (Basel) (01-07-2024)“…Cardiac death is the second most common cause of death among patients with acute ischemic stroke (IS), following neurological death resulting directly from…”
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An integrative strategy for discovery of functional compound combination from Traditional Chinese Medicine: Danhong Injection as a model
Published in Biomedicine & pharmacotherapy (01-06-2021)“…Traditional Chinese Medicine formulas, which are usually considered exerting their holistic clinical benefits via multi-component, multi-target manner, are…”
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Simultaneous Optimization of the Ultrasonic Extraction Method and Determination of the Antioxidant Activities of Hydroxysafflor Yellow A and Anhydrosafflor Yellow B from Safflower Using a Response Surface Methodology
Published in Molecules (Basel, Switzerland) (09-03-2020)“…An evaluation of the ultrasonic extraction process and the antioxidant activities of hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB) from…”
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