Search Results - "Yang, Ji'e"
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Gasdermin D mediates endoplasmic reticulum stress via FAM134B to regulate cardiomyocyte autophagy and apoptosis in doxorubicin-induced cardiotoxicity
Published in Cell death & disease (26-10-2022)“…Cardiomyocyte pyroptosis and apoptosis play a vital role in the pathophysiology of several cardiovascular diseases. Our recent study revealed that gasdermin D…”
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Relationship between body mass index and outcomes of coronary artery disease in Asian population: Insight from the FOCUS registry
Published in International journal of cardiology (01-02-2020)“…Obesity is often considered as a risk factor of cardiovascular events, but recent researches showed conflicting results regarding to the effect of body weight…”
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Aldehyde Dehydrogenase 2 (ALDH2) Elicits Protection against Pulmonary Hypertension via Inhibition of ERK1/2-Mediated Autophagy
Published in Oxidative medicine and cellular longevity (20-06-2022)“…Pulmonary hypertension (PH) is caused by chronic hypoxia that induces the migration and proliferation of pulmonary arterial smooth muscle cells (PASMCs),…”
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Sex-based influence on clinical outcomes after drug-eluting stent implantation in real-world patients: insight from the FOCUS registry
Published in Annals of medicine (Helsinki) (03-04-2017)“…To investigate the impact of sex on clinical outcomes after drug-eluting stent (DES) implantation in real-world patients. A total number of 4720 patients (3365…”
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CCL11 released by GSDMD-mediated macrophage pyroptosis regulates angiogenesis after hindlimb ischemia
Published in Cell death discovery (21-06-2024)“…Peripheral vascular disease (PVD) is an emerging public health burden with a high rate of disability and mortality. Gasdermin D (GSDMD) has been reported to…”
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Optimal strategy of primary percutaneous coronary intervention for acute myocardial infarction due to unprotected left main coronary artery occlusion (OPTIMAL): study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (08-03-2019)“…Primary percutaneous coronary intervention (PCI) for patients presenting with acute myocardial infarction (AMI) caused by left main coronary artery occlusion…”
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Clinical Characteristics and Outcomes in Asian Patients With Premature Coronary Artery Disease: Insight From the FOCUS Registry
Published in Angiology (01-07-2019)“…Objectives: Premature coronary artery disease (PCAD) is increasingly common in Asian countries; however, less is known regarding its characteristics and…”
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Safety and Efficacy of Percutaneous Coronary Intervention via Transradial Versus Transfemoral Approach in Bypass Grafts
Published in Angiology (01-02-2018)“…We compared the efficacy and safety of the transradial approach percutaneous coronary intervention (TRA-PCI) and transfemoral approach percutaneous coronary…”
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Long-term performance of the second-generation cobalt-chromium sirolimus-eluting stents in real-world clinical practice: 3-year clinical outcomes from the prospective multicenter FOCUS registry
Published in Journal of thoracic disease (01-07-2016)“…The short- and mid-term outcomes of the second-generation cobalt-chromium sirolimus-eluting stent (CoCr-SES) in real-world patients had been reported…”
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Optimal interventional strategy for the treatment of coronary in-stent restenosis
Published in Journal of thoracic disease (01-10-2015)Get full text
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GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury
Published in Circulation research (23-07-2021)“…[Figure: see text]…”
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Activation of CXCL16/CXCR6 axis aggravates cardiac ischemia/reperfusion injury by recruiting the IL‐17a‐producing CD1d+ T cells
Published in Clinical and translational medicine (01-02-2021)“…CXCL16 is a proinflammatory chemokine that widely expressed in endothelial cells, vascular smooth muscle cells, and fibroblasts.2 CXCL16 is a novel diagnostic…”
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The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction
Published in International immunopharmacology (01-06-2022)“…•H-151 treatment can preserve myocardial function and attenuate cardiac fibrosis in murine myocardial infarction.•H-151 treatment can inhibit the…”
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Gender-Related Differences in Clinical Characteristics and Outcomes of Premature Coronary Artery Disease: Insight from the FOCUS Registry
Published in Journal of interventional cardiology (2019)“…Introduction. Although coronary artery disease (CAD) presentations and clinical outcomes differ by sex, little is known about premature CAD (PCAD). The present…”
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Galangin alleviated myocardial ischemia-reperfusion injury by enhancing autophagic flux and inhibiting inflammation
Published in European journal of pharmacology (15-04-2023)“…Autophagy is critically involved in myocardial ischemia-reperfusion (I/R). Autophagy inhibition exacerbates myocardial I/R injury. Few effective agents target…”
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Neutrophil‐derived advanced glycation end products‐Nε‐(carboxymethyl) lysine promotes RIP3‐mediated myocardial necroptosis via RAGE and exacerbates myocardial ischemia/reperfusion injury
Published in The FASEB journal (01-12-2019)“…Nε‐(carboxymethyl) lysine (CML), the major member of advanced glycation end products, was widely studied in diabetic complications and aging‐associated…”
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Comparison of long-term clinical outcomes after the second-generation cobalt-chromium sirolimus-eluting stents implantation in diabetic versus non-diabetic patients: a subgroup analysis from the prospective FOCUS registry
Published in Annals of medicine (Helsinki) (02-04-2016)“…Diabetes mellitus (DM) was broadly acknowledged as a risk factor for adverse events after coronary stent implantation. However, the role of DM in patients…”
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Prospective multicentre open-label randomised controlled trial of 3-month versus 12-month dual antiplatelet therapy after implantation of the new generation biodegradable polymer sirolimus TARGET-eluting coronary stent: protocol of the TARGET DAPT trial
Published in BMJ open (17-12-2019)“…IntroductionDual antiplatelet therapy (DAPT) with aspirin and thienopyridine is required after placement of coronary stents to prevent thrombotic…”
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GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury
Published in Circulation research (01-06-2021)Get full text
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