Search Results - "Yang, Jeong Yeh"
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An automated platform for the enzyme-mediated assembly of complex oligosaccharides
Published in Nature chemistry (01-03-2019)“…An automated platform that can synthesize a wide range of complex carbohydrates will greatly increase their accessibility and should facilitate progress in…”
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Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy
Published in Nature chemistry (01-02-2019)“…Contemporary chemoenzymatic approaches can provide highly complex multi-antennary N -linked glycans. These procedures are, however, very demanding and…”
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Multiple Arabidopsis galacturonosyltransferases synthesize polymeric homogalacturonan by oligosaccharide acceptor‐dependent or de novo synthesis
Published in The Plant journal : for cell and molecular biology (01-03-2022)“…SUMMARY Homogalacturonan (HG), the most abundant pectic glycan, functions as a cell wall structural and signaling molecule essential for plant growth,…”
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Identification of an algal xylan synthase indicates that there is functional orthology between algal and plant cell wall biosynthesis
Published in The New phytologist (01-05-2018)“…Insights into the evolution of plant cell walls have important implications for comprehending these diverse and abundant biological structures. In order to…”
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Structural, mutagenic and in silico studies of xyloglucan fucosylation in Arabidopsis thaliana suggest a water‐mediated mechanism
Published in The Plant journal : for cell and molecular biology (01-09-2017)“…Summary The mechanistic underpinnings of the complex process of plant polysaccharide biosynthesis are poorly understood, largely because of the resistance of…”
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Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses
Published in Nature communications (14-09-2021)“…During circulation in humans and natural selection to escape antibody recognition for decades, A/H3N2 influenza viruses emerged with altered receptor…”
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Expression system for structural and functional studies of human glycosylation enzymes
Published in Nature chemical biology (01-02-2018)“…A modular protein expression system enables the structural and functional characterization of human glycosyltransferases, glycoside hydrolases and other…”
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Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration
Published in Nature communications (04-05-2022)“…Human Milk Oligosaccharides (HMOs) are abundant carbohydrates fundamental to infant health and development. Although these oligosaccharides were discovered…”
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A Glycan Array‐Based Assay for the Identification and Characterization of Plant Glycosyltransferases
Published in Angewandte Chemie (International ed.) (20-07-2020)“…Growing plants with modified cell wall compositions is a promising strategy to improve resistance to pathogens, increase biomass digestibility, and tune other…”
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Identification of Key Enzymes for Pectin Synthesis in Seed Mucilage
Published in Plant physiology (Bethesda) (01-11-2018)“…Pectin is a vital component of the plant cell wall and provides the molecular glue that maintains cell-cell adhesion, among other functions. As the most…”
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Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes
Published in Phytotherapy research (01-10-2008)“…Resveratrol, a phytoallexin, has recently been reported to slow aging by acting as a sirtuin activator. Resveratrol also has a wide range of pharmacological…”
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Effect of resveratrol on fat mobilization
Published in Annals of the New York Academy of Sciences (01-01-2011)“…Higher levels of body fat are associated with increased risk for development of numerous adverse health conditions. Phytochemicals are potential agents to…”
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Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway
Published in Nature communications (14-11-2017)“…Immunoglobulin G (IgG) is a major effector molecule of the human immune response, and aberrations in IgG glycosylation are linked to various diseases. However,…”
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Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes
Published in PloS one (21-09-2015)“…Beta-adrenergic activation stimulates uncoupling protein 1 (UCP1), enhancing metabolic rate. In vitro, most work has studied brown adipocytes, however, few…”
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Chemoenzymatic Tagging of Tn/TF/STF Antigens in Living Systems
Published in Israel journal of chemistry (01-10-2023)“…Truncated mucin‐type O‐glycans, such as Tn‐associated antigens, are aberrantly expressed biomarkers of cancer, but remain challenging to target. Reactive…”
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NMR Resonance Assignment Methodology: Characterizing Large Sparsely Labeled Glycoproteins
Published in Journal of molecular biology (31-05-2019)“…Characterization of proteins using NMR methods begins with assignment of resonances to specific residues. This is usually accomplished using sequential…”
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Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist
Published in Science advances (01-05-2016)“…Ca(2+)-sensing receptors (CaSRs) modulate calcium and magnesium homeostasis and many (patho)physiological processes by responding to extracellular stimuli,…”
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Measurement of residual dipolar couplings in methyl groups via carbon detection
Published in Journal of biomolecular NMR (01-04-2019)“…Residual dipolar couplings (RDCs) provide both structural and dynamical information useful in the characterization of biological macromolecules. While most…”
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A dietary phytochemical blend prevents liver damage associated with adipose tissue mobilization in ovariectomized rats
Published in Obesity (Silver Spring, Md.) (01-01-2015)“…Objective Menopausal reduction in estrogen causes increased adipose accumulation, leading many to turn to dietary supplements to prevent and treat such…”
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Guggulsterone Inhibits Adipocyte Differentiation and Induces Apoptosis in 3T3-L1 Cells
Published in Obesity (Silver Spring, Md.) (01-01-2008)“…Objective: To determine the effects of guggulsterone (GS), the active substance in guggulipid, on apoptosis, adipogenesis, and lipolysis using 3T3‐L1 cells…”
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