Search Results - "Yang, Huisuk"
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Droplet-born air blowing: Novel dissolving microneedle fabrication
Published in Journal of controlled release (28-09-2013)“…The microneedle-mediated drug delivery system has been developed to provide painless self-administration of drugs in a patient-friendly manner. Current…”
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The Troy Microneedle: A Rapidly Separating, Dissolving Microneedle Formed by Cyclic Contact and Drying on the Pillar (CCDP)
Published in PloS one (26-08-2015)“…In dissolving microneedle (DMN)-mediated therapy, complete and rapid delivery of DMNs is critical for the desired efficacy. Traditional patch-based DMN…”
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Effects of dissolving microneedle fabrication parameters on the activity of encapsulated lysozyme
Published in European journal of pharmaceutical sciences (30-05-2018)“…Dissolving microneedle (DMN) is referred to a microscale needle that encapsulates drug(s) within a biodegradable polymer matrix and delivers it into the skin…”
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Dissolving Candlelit Microneedle for Chronic Inflammatory Skin Diseases
Published in Advanced science (01-07-2021)“…Chronic inflammatory skin diseases (CISDs) negatively impact a large number of patients. Injection of triamcinolone acetonide (TA), an anti‐inflammatory…”
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Solvent-Free Polycaprolactone Dissolving Microneedles Generated via the Thermal Melting Method for the Sustained Release of Capsaicin
Published in Micromachines (Basel) (08-02-2021)“…(1) Background: Dissolving microneedles (DMNs), a transdermal drug delivery system, have been developed to treat various diseases in a minimally invasive,…”
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Centrifugal Lithography: Self‐Shaping of Polymer Microstructures Encapsulating Biopharmaceutics by Centrifuging Polymer Drops
Published in Advanced healthcare materials (01-10-2017)“…Polymeric microstructures encapsulating biopharmaceutics must be fabricated in a controlled environment to preserve the biological activity. There is…”
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Development of Lidocaine-Loaded Dissolving Microneedle for Rapid and Efficient Local Anesthesia
Published in Pharmaceutics (09-11-2020)“…Lidocaine is a local anesthetic agent used in the form of injection and topical cream. However, these formulation types have limitations of being either…”
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Development of Clinical Weekly-Dose Teriparatide Acetate Encapsulated Dissolving Microneedle Patch for Efficient Treatment of Osteoporosis
Published in Polymers (26-09-2022)“…Teriparatide acetate (TA), which directly promotes bone formation, is subcutaneously injected to treat osteoporosis. In this study, TA with a once-weekly…”
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Film-trigger applicator (FTA) for improved skin penetration of microneedle using punching force of carboxymethyl cellulose film acting as a microneedle applicator
Published in Biomaterials research (05-10-2022)“…Abstract Background Dissolving microneedle (DMN) is a transdermal drug delivery system that creates pore in the skin and directly deliver drug through the pore…”
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Optimization of Layered Dissolving Microneedle for Sustained Drug Delivery Using Heat-Melted Poly(Lactic-Co-glycolic Acid)
Published in Pharmaceutics (10-07-2021)“…Dissolving microneedles (DMNs) have been used as an alternative drug delivery system to deliver therapeutics across the skin barrier in a painless manner. In…”
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Enhanced Micro-Channeling System via Dissolving Microneedle to Improve Transdermal Serum Delivery for Various Clinical Skincare Treatments
Published in Pharmaceutics (01-12-2022)“…Topical liquid formulations, dissolving microneedles (DMNs), and microscale needles composed of biodegradable materials have been widely used for the…”
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Scalp Micro-Pigmentation via Transcutaneous Implantation of Flexible Tissue Interlocking Biodegradable Microneedles
Published in Pharmaceutics (23-10-2019)“…Alopecia, characterized by hair follicle blockage and hair loss, disrupts the normal cycle of hair growth. Although not a life-threatening condition, a growing…”
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4-n-butylresorcinol dissolving microneedle patch for skin depigmentation: a randomized, double-blind, placebo-controlled trial
Published in Journal of cosmetic dermatology (01-03-2016)“…Summary Background For effective skin depigmentation, the skin depigmentation agent must be delivered to melanocytes, where melanin is synthesized. Although…”
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Transdermal finasteride delivery via powder-carrying microneedles with a diffusion enhancer to treat androgenetic alopecia
Published in Journal of controlled release (28-12-2019)“…[Display omitted] Androgenetic alopecia is a common form of scalp hair loss that affects men in their mid-twenties and increases with age. Finasteride (FNS)…”
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Implantable powder-carrying microneedles for transdermal delivery of high-dose insulin with enhanced activity
Published in Biomaterials (01-02-2020)“…Recently, numerous transdermal drug delivery systems have been developed for safe and efficient delivery of biopharmaceuticals. Dissolving microneedles (DMNs)…”
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High‐Dose Steroid Dissolving Microneedle for Relieving Atopic Dermatitis
Published in Advanced healthcare materials (01-04-2021)“…Dissolving microneedles (DMN) supplemented with therapeutic molecules have been developed to enhance transdermal delivery efficiency of topically applied drugs…”
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Innovative polymeric system (IPS) for solvent-free lipophilic drug transdermal delivery via dissolving microneedles
Published in Journal of controlled release (10-02-2016)“…Lipophilic drugs are potential drug candidates during drug development. However, due to the need for hazardous organic solvents for their solubilization, these…”
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Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth
Published in Biomaterials (01-06-2018)“…The interest in alternative material systems and delivery methods for treatment of androgenetic alopecia has been increasing in the recent decades. Topical…”
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Hyaluronic acid-based minocycline-loaded dissolving microneedle: Innovation in local minocycline delivery for periodontitis
Published in Carbohydrate polymers (01-02-2025)Get full text
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Effects of two droplet-based dissolving microneedle manufacturing methods on the activity of encapsulated epidermal growth factor and ascorbic acid
Published in European journal of pharmaceutical sciences (01-03-2018)“…Dissolving microneedle (DMN) is an attractive, minimally invasive transdermal drug delivery technology. The drugs encapsulated in the DMNs are exposed to a…”
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