Search Results - "Yang, Huangtian"
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Uncoupling protein 3 mediates H₂O₂ preconditioning-afforded cardioprotection through the inhibition of MPTP opening
Published in Cardiovascular research (01-02-2015)“…Uncoupling protein 3 (UCP3), located in the mitochondrial inner membrane, is cardioprotective, but its mechanisms of preserving mitochondrial function during…”
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Cmarr/miR-540-3p axis promotes cardiomyocyte maturation transition by orchestrating Dtna expression
Published in Molecular therapy. Nucleic acids (13-09-2022)“…The immature phenotype of embryonic stem cell-derived cardiomyocytes (ESC-CMs) limits their application. However, the molecular mechanisms of cardiomyocyte…”
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Chitosan/Calcium Silicate Cardiac Patch Stimulates Cardiomyocyte Activity and Myocardial Performance after Infarction by Synergistic Effect of Bioactive Ions and Aligned Nanostructure
Published in ACS applied materials & interfaces (09-01-2019)“…Cardiac tissue engineering (CTE) remains a great challenge to construct a cell-inductive scaffold that has positive effects on cardiac cell behaviors and…”
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Therapeutic delivery of microRNA-125a-5p oligonucleotides improves recovery from myocardial ischemia/reperfusion injury in mice and swine
Published in Theranostics (2023)“…Clinical application of mesenchymal stem cells (MSCs) and MSC-derived exosomes (MSC-Exos) to alleviate myocardial ischemia/reperfusion (I/R) injury is…”
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Modelling myocardial ischemia/reperfusion injury with inflammatory response in human ventricular cardiac organoids
Published in Cell proliferation (08-10-2024)“…Current therapeutic drug exploring targeting at myocardial ischemia/reperfusion (I/R) injury is limited due to the lack of humanized cardiac models that…”
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Expression profile of circular RNAs in myocardial ischemia/reperfusion with and without intermittent hypobaric hypoxia preconditioning
Published in Science China. Life sciences (01-08-2019)Get full text
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PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells
Published in Aging (Albany, NY.) (28-04-2020)“…Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have great potential in biomedical applications. However, the immature state of cardiomyocytes…”
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Abstract 257: Berbamine Postconditioning Protects the Heart From Ischemia/Reperfusion Injury Through the Regulation of Autophagy During Reperfusion
Published in Circulation research (17-07-2015)“…Abstract only Myocardial infarction resulting from coronary atherosclerosis is the leading cause of death in modern society. Reperfusion is an essential…”
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GW28-e0862 Comparison of Immune Suppression Strategies for Transplantation of human Embryonic Stem Cell-Derived Cardiovascular Progenitor Cells in Postmyocardial Infarcted Nonhuman Primates
Published in Journal of the American College of Cardiology (17-10-2017)“…To determine suitable immunosuppression strategies for human pluripotent stem cell-derived cardiac lineage cells in nonhuman primates. MI was established in…”
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Knockdown of Nucleosome Assembly Protein 1‐Like 1 Induces Mesoderm Formation and Cardiomyogenesis Via Notch Signaling in Murine‐Induced Pluripotent Stem Cells
Published in Stem cells (Dayton, Ohio) (01-07-2014)“…Low efficiency of cardiomyocyte differentiation from induced pluripotent stem cells (iPSCs) hinders the clinical application of iPSC technology for cardiac…”
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Beta‐adrenergic signals regulate cardiac differentiation of mouse embryonic stem cells via mitogen‐activated protein kinase pathways
Published in Development, growth & differentiation (01-08-2011)“…As embryonic stem cell‐derived cardiomyocytes (ESC‐CMs) have the potential to be used in cell replacement therapy, an understanding of the signaling mechanisms…”
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Progenitor/stem cell transplantation for repair of myocardial infarction: Hype or hope?
Published in Annals of palliative medicine (01-01-2012)“…Despite significant therapeutic advances, heart failure remains the predominant cause of mortality worldwide. Currently, progenitor/stem cell biology holds…”
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Abstract 241: Intermittent Hypoxia Protects Cardiomyocytes Against Ischemia/Reperfusion-Induced Ca 2+ Overload and Contraction Suppression via Activation of α 1b -adrenoceptors
Published in Circulation (New York, N.Y.) (28-10-2008)“…Abstract only We have demonstrated that long-term training to intermittent high altitude hypoxia (IH) protects hearts against ischemia-reperfusion…”
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Abstract 11172: Human Embryonic Stem Cell-Derived Cardiovascular Progenitors Repair Myocardial Infarction Through Modulation of Macrophage Plasticity
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionMyocardial ischemic injury-induced inflammatory cascade is involved in exacerbating scar formation and repairing damage, while the contribution of…”
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Regulation of Ca2+ signaling during differentiation of embryonic stem cells into cardiomyocytes and neuronal cells
Published in Cell research (04-08-2008)Get full text
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