Search Results - "Yang, Hee Won"
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The structural changes of a local tourism network: comparison of before and after COVID-19
Published in Current issues in tourism (02-12-2021)“…The COVID-19 pandemic has caused dramatic changes on a global scale. According to the United Nations World Tourism Organization (2020), the restricted movement…”
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Cooperative Activation of PI3K by Ras and Rho Family Small GTPases
Published in Molecular cell (27-07-2012)“…Phosphoinositide 3-kinases (PI3Ks) and Ras and Rho family small GTPases are key regulators of cell polarization, motility, and chemotaxis. They influence each…”
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3
What drives tourists to take a digital‐free tourism?
Published in The international journal of tourism research (01-07-2024)“…This study utilizes a combined model of two social cognitive models, protection motivation theory and theory of planned behavior, to analyze how smartphone use…”
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1.2-GHz repetition rate, diode-pumped femtosecond Yb:KYW laser mode-locked by a carbon nanotube saturable absorber mirror
Published in Optics express (31-12-2012)“…We demonstrate a 1.2-GHz repetition rate, diode-pumped, self-starting, 168-fs (FWHM) pulsewidth Yb:KYW laser mode-locked by a carbon nanotube (CNT) saturable…”
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5
Interannual variation of the southern limit in the Yellow Sea Bottom Cold Water and its causes
Published in Journal of marine systems (01-11-2014)“…The Yellow Sea Bottom Cold Water (YSBCW) occupies a wide region below the Yellow Sea (YS) thermocline in summer. The southern limit of the YSBCW shows…”
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CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition
Published in Scientific reports (07-10-2022)“…External signaling controls cell-cycle entry until cells irreversibly commit to the cell cycle to ensure faithful DNA replication. This process is tightly…”
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Non-canonical pathway for Rb inactivation and external signaling coordinate cell-cycle entry without CDK4/6 activity
Published in Nature communications (29-11-2023)“…Cyclin-dependent kinases 4 and 6 (CDK4/6) are critical for initiating cell proliferation by inactivating the retinoblastoma (Rb) protein. However, mammalian…”
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Locally excitable Cdc42 signals steer cells during chemotaxis
Published in Nature cell biology (01-02-2016)“…Neutrophils and other amoeboid cells chemotax by steering their front ends towards chemoattractant. Although Ras, Rac, Cdc42 and RhoA small GTPases all…”
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Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells
Published in Nature cell biology (01-12-2016)“…The development and maintenance of tissues requires collective cell movement, during which neighbouring cells coordinate the polarity of their migration…”
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10
Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1
Published in Molecular cell (21-11-2019)“…Cells escape the need for mitogens at a restriction point several hours before entering S phase. The restriction point has been proposed to result from CDK4/6…”
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Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation
Published in The Journal of clinical investigation (01-09-2016)“…Angiopoietin-2 (ANG2) regulates blood vessel remodeling in many pathological conditions through differential effects on Tie2 signaling. While ANG2 competes…”
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The Impact of the COVID-19 Pandemic on Tourists' WTP: Using the Contingent Valuation Method
Published in International journal of environmental research and public health (14-08-2021)“…This study estimated tourists' willingness to pay (WTP) for tourist sites or facilities in the prolonged COVID-19 pandemic by applying the dichotomous…”
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13
Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma
Published in Nature communications (01-09-2021)“…Aurora kinase A (AURKA) has emerged as a drug target for glioblastoma (GBM). However, resistance to therapy remains a critical issue. By integration of…”
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14
Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity
Published in Nature communications (20-10-2020)“…Cell-cycle entry relies on an orderly progression of signaling events. To start, cells first activate the kinase cyclin D-CDK4/6, which leads to eventual…”
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Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation
Published in eLife (07-04-2020)“…Mammalian cells typically start the cell-cycle entry program by activating cyclin-dependent protein kinase 4/6 (CDK4/6). CDK4/6 activity is clinically relevant…”
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Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization
Published in Developmental cell (22-04-2019)“…Efficient chemotaxis requires rapid coordination between different parts of the cell in response to changing directional cues. Here, we investigate the…”
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Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment
Published in The Journal of clinical investigation (16-10-2023)“…Improving the management of metastasis in pancreatic neuroendocrine tumors (PanNETs) is critical, as nearly half of patients with PanNETs present with liver…”
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Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
Published in Cell reports (Cambridge) (28-11-2023)“…Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are key therapeutic agents in the management of metastatic hormone-receptor-positive breast cancer…”
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Association between serum free hemoglobin level and cerebral white matter hyperintensity volume in older adults
Published in Scientific reports (28-02-2022)“…The association between serum free hemoglobin (sfHb) level and white matter hyperintensity (WMH) volume is controversial. This study is to examine this…”
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Exploring age-related changes in saccades during cognitive tasks in healthy adults
Published in Frontiers in behavioral neuroscience (05-01-2024)“…Although eye movements such as saccades are related to internal cognitive processes and are independent of visual processing, few studies have investigated…”
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