Search Results - "Yang, GuangFu"

A highly selective and recyclable NO-responsive nanochannel based on a spiroring opening−closing reaction strategy by Sun, Yao, Chen, Sen, Chen, Xiaoya, Xu, Yuling, Zhang, Siyun, Ouyang, Qingying, Yang, Guangfu, Li, Haibing

“…Endogenous nitric oxide (NO) is an important messenger molecule, which can directly activate K + transmission and cause relaxation of vascular smooth muscle…”
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Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy by Sun, Yue, Ding, Feng, Zhou, Zhixuan, Li, Chonglu, Pu, Maoping, Xu, Yuling, Zhan, Yibei, Lu, Xiaoju, Li, Haibing, Yang, Guangfu, Sun, Yao, Stang, Peter J.

“…Fluorescent theranostics probes at the second near-IR region (NIR-II; 1.0–1.7 μm) are in high demand for precise theranostics that minimize autofluorescence,…”
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A Hg(II)-specific probe for imaging application in living systems and quantitative analysis in environmental/food samples by Li, Guangjin, Wang, Jiali, Li, Dongyang, Liu, Shenghua, Yin, Jun, Lai, Zhibing, Yang, Guangfu

“…A small molecule fluorescent probe has gained the multi-application in mercury ion detection, whether they are organisms or inert objects. [Display omitted]…”
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Iron-Catalyzed Hydrogenation of Bicarbonates and Carbon Dioxide to Formates by Zhu, Fengxiang, Zhu-Ge, Ling, Yang, Guangfu, Zhou, Shaolin

“…The catalytic hydrogenation of carbon dioxide and bicarbonate to formate has been explored extensively. The vast majority of the known active catalyst systems…”
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Ametoctradin is a potent Qo site inhibitor of the mitochondrial respiration complex III by Zhu, Xiaolei, Zhang, Mengmeng, Liu, Jingjing, Ge, Jingming, Yang, Guangfu

“…Ametoctradin is a new Oomycete-specific fungicide under development by BASF. It is a potent inhibitor of the bc1 complex in mitochondrial respiration. However,…”
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Freely Accessible Chemical Database Resources of Compounds for In Silico Drug Discovery by Yang, JingFang, Wang, Di, Jia, Chenyang, Wang, Mengyao, Hao, GeFei, Yang, GuangFu

“…In silico drug discovery has been proved to be a solidly established key component in early drug discovery. However, this task is hampered by the limitation of…”
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Protocol for hit-to-lead optimization of compounds by auto in silico ligand directing evolution (AILDE) approach by Mei, Longcan, Wu, Fengxu, Hao, Gefei, Yang, Guangfu

“…Hit-to-lead (H2L) optimization is crucial for drug design, which has become an increasing concern in medicinal chemistry. A virtual screening strategy of auto…”
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pH-Responsive Surface Activity and Solubilization with Novel Pyrrolidone-Based Gemini Surfactants by Jiang, Zan, Li, Xuefeng, Yang, Guangfu, Cheng, Li, Cai, Bo, Yang, Yi, Dong, Jinfeng

“…A new series of pH-responsive Gemini surfactants with 2-pyrrolidone head groups, N,N ′-dialkyl- N,N ′-di(ethyl-2-pyrrolidone)ethylenediamine (Di-C n P, where n…”
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Auto In Silico Ligand Directing Evolution to Facilitate the Rapid and Efficient Discovery of Drug Lead by Wu, Fengxu, Zhuo, Linsheng, Wang, Fan, Huang, Wei, Hao, Gefei, Yang, Guangfu

“…Motivated by the growing demand for reducing the chemical optimization burden of H2L, we developed auto in silico ligand directing evolution…”
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The structure of 4-hydroxylphenylpyruvate dioxygenase complexed with 4-hydroxylphenylpyruvic acid reveals an unexpected inhibition mechanism by Wang, Xiaoning, Lin, Hongyan, Liu, Junjun, Zhao, Xinyun, Chen, Xi, Yang, Wenchao, Yang, Guangfu, Zhan, Chang-guo

“…The substrate resists the electrophilic attack of the bound dioxygen by the trim of its phenyl ring. [Display omitted] 4-Hydroxyphenylpyruvate dioxygenase…”
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CROP PROTECTION OPENS UP NEW ERA OF CONSERVATION AND UTILIZATION OF GREEN OPTIONS by WANG, Guirong, WANG, Yuanchao, YANG, Guangfu, WU, Kongming

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DISCOVERY OF TRIKETONE-QUINOXALINE HYBRIDS AS POTENT HPPD INHIBITORS USING STRUCTURE-BASED DRUG DESIGN by ZHENG, Baifeng, YAN, Yaochao, FU, Can, HUANG, Guangyi, ZHAO, Long, CHEN, Qiong, QU, Renyu, YANG, Guangfu

“…* HPPD is one of the most promising targets for new herbicides. * A family of novel HPPD inhibitors based on the triketone-quinoxaline scaffold was designed…”
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Computational Redesign of Human Butyrylcholinesterase for Anticocaine Medication by Yongmei Pan, Daquan Gao, Wenchao Yang, Hoon Cho, Guangfu Yang, Tai, Hsin-Hsiung, Chang-Guo Zhan

“…Molecular dynamics was used to simulate the transition state for the first chemical reaction step (TS1) of cocaine hydrolysis catalyzed by human…”
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Cationic corrole derivatives: a new family of G-quadruplex inducing and stabilizing ligands by Fu, Boqiao, Huang, Jing, Ren, Lige, Weng, Xiaocheng, Zhou, Yangyang, Du, Yuhao, Wu, Xiaojun, Zhou, Xiang, Yang, Guangfu

“…Water-soluble cationic corrole derivatives were designed and synthesized, and the first observation of their interactions with the telomeric G-quadruplex was…”
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InBr3-catalyzed cyclization of glycosides with arylamines by Wang, Pingyuan, Wang, Meining, Zhang, Xuefeng, Yang, Guangfu, Zhang, Ao

“…Glycals have served as excellent substrates in the glycosidation reactions with arylamines to construct both C–C and C–N linkages simultaneously. However, the…”
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Synthesis and biological activity of novel phenyltriazolinone derivatives by Wu, Qiongyou, Wang, Guodong, Huang, Shaowei, Lin, Long, Yang, Guangfu

“…Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives…”
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Development of an Improved Liquid Phase Microextraction Technique and Its Application in the Analysis of Flumetsulam and Its Two Analogous Herbicides in Soil by Xu, Hui, Pan, Wenhui, Song, Dandan, Yang, Guangfu

“…An improved liquid phase microextraction (LPME) technique has been developed. As part of this technique, analytes were extracted into an extractant microdrop…”
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Design, Synthesis, and Bioevaluation of Novel Strobilurin Derivatives by 朱晓磊 王福 李慧 杨文超 陈琼 杨光富

“…Strobilurins are one of the most important natural products with fungicidal activities and well known for their novel action mode, broad fungicidal spectrum,…”
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A DFT-based QSARs study of protoporphyrinogen oxidase inhibitors: phenyl triazolinones by Zhang, Li, Wan, Jian, Yang, Guangfu

“…Based on a set of quantum chemical descriptors obtained at the B3LYP/6-31G(d,p) level, a quantitative structure–activity relationships study has been carried…”
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Binding Interaction Analysis of the Active Site and Its Inhibitors for Neuraminidase (N1 Subtype) of Human Influenza Virus by the Integration of Molecular Docking, FMO Calculation and 3D-QSAR CoMFA Modeling by Zhang, Qingye, Yang, Jiaoyan, Liang, Kun, Feng, Lingling, Li, Sanpin, Wan, Jian, Xu, Xin, Yang, Guangfu, Liu, Deli, Yang, Shao

“…Recently, the worldwide spread of A/H5N1 avian influenza with high virulence has highlighted the potential threat of human influenza pandemic. Tamiflu and…”
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