Search Results - "Yang, Fenfang"
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Effects of soybean meal fermented by L. plantarum, B. subtilis and S. cerevisieae on growth, immune function and intestinal morphology in weaned piglets
Published in Microbial cell factories (09-11-2017)“…The present study compared the effects of soybean meal fermented by three different probiotics organisms with non-fermented soybean meal on growth performance,…”
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Lean non-alcoholic fatty liver disease (Lean-NAFLD) and the development of metabolic syndrome: a retrospective study
Published in Scientific reports (29-06-2022)“…Lean NAFLD is a special phenotypic closely correlated with metabolic syndrome (MS). The aim of this study is to investigate the MS development and the gender…”
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Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML
Published in Cell communication and signaling (22-09-2023)“…Chemoresistance poses a significant impediment to effective treatment strategies for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Our…”
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Clonal MDS/AML cells with enhanced TWIST1 expression reprogram the differentiation of bone marrow MSCs
Published in Redox biology (01-11-2023)“…Bone marrow-derived mesenchymal stem cells (BMMSCs) derived from myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) patients often show a shift in…”
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Reevaluating Adiponectin's impact on obesity hypertension: a Chinese case-control study
Published in BMC cardiovascular disorders (13-04-2024)“…Obesity and hypertension are major risk factors for cardiovascular diseases that affect millions of people worldwide. Both conditions are associated with…”
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Preparation, characterization, and release behavior of ceftiofur-loaded gelatin-based microspheres
Published in Journal of applied polymer science (15-11-2013)“…ABSTRACT Drug‐loaded microspheres prepared from biomacromolecules have received considerable interest. In this article, we report a facile method for preparing…”
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In vivo investigation of ceftiofur-loaded gelatin and PLGA microspheres in beagle dogs
Published in Journal of materials science. Materials in medicine (01-04-2013)“…Drug delivery systems based on polymer microspheres have received considerable attention. Ceftiofur sodium and ceftiofur hydrochloride is widely used for the…”
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Preparation of lung targeting microspheres of gelatin ceftiofur alkali
Published in Journal of Wuhan University of Technology. Materials science edition (01-04-2013)“…Gelatin ceftiofur alkali microsphere was prepared to observe its characteristics and evaluate preservation conditions. The glutaraldehyde was increased and the…”
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Helical Stabilization of Peptide Macrocycles by Stapled Architectures
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Over the past two decades, significant efforts have invested in the development of strategies for the stabilization of macrocyclic peptides with α-helix…”
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The synergistic function of long and short forms of β4GalT1 in p53-mediated drug resistance in bladder cancer cells
Published in Biochimica et biophysica acta. Molecular cell research (01-02-2023)“…β1,4-galactosyltransferase-1 (β4GalT1) is a type II membrane protein that catalyzes the transfer of galactose (Gal) from UDP-Gal to N-acetylglucosamine…”
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Targeted Biomolecule Regulation Platform: A Split-and-Mix PROTAC Approach
Published in Journal of the American Chemical Society (12-04-2023)“…The development of bifunction al molecules, which can enable targeted RNA degradation, targeted protein acetylation, or targeted protein degradation, remains a…”
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Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction
Published in Journal of medicinal chemistry (22-09-2022)“…Blocking the interaction of MTDH/SND1 complex is an attractive strategy for cancer therapeutics. In this work, we designed and obtained a novel class of potent…”
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Selective Protein of Interest Degradation through the Split-and-Mix Liposome Proteolysis Targeting Chimera Approach
Published in Journal of the American Chemical Society (11-10-2023)“…Proteolysis Targeting Chimera (PROTAC) technology represents a promising new approach for target protein degradation using a cellular ubiquitin-proteasome…”
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A Novel Lysosome Targeting Chimera for Targeted Protein Degradation via Split-and-Mix Strategy
Published in ACS chemical biology (17-05-2024)“…Targeted protein degradation is becoming more and more important in the field of drug development. Compared with proteasomal-based degraders, lysosomal-based…”
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A Comparison of Two Methods for the Preparation Cefquinome-Loaded Gelatin Microspheres for Lung Targeting
Published in Pharmaceutical research (01-02-2018)“…Purpose The aim of this study was to prepare CEQ-loaded gelatin microspheres and compare two preparation methods, evaluate targeting to the lungs. Methods…”
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A Peptide-Based Ligand-Directed Chemistry Enables Protein Functionalization
Published in Organic letters (07-10-2022)“…The ligand-directed (LD) chemistry provides powerful tools for site-specific modification of proteins. We utilized a peptide with an appended methionine (Met)…”
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Colorable role of interleukin (IL)-6 in obesity hypertension: A hint from a Chinese adult case-control study
Published in Cytokine (Philadelphia, Pa.) (01-08-2023)“…Obesity and hypertension are major risk factors for cardiovascular diseases that affect millions of people worldwide. Both conditions are associated with…”
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Cefquinome-Loaded Microsphere Formulations in Protection against Pneumonia with Klebsiella pneumonia Infection and Inflammatory Response in Rats
Published in Pharmaceutical research (01-05-2019)“…Purpose This study aimed to compare in vivo activity between cefquinome (CEQ)-loaded poly lactic-co-glycolic acid (PLGA) microspheres (CEQ-PLGA-MS) and CEQ…”
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Multi-Omics Approaches Identify Necroptosis‑Related Prognostic Signature and Associated Regulatory Axis in Cervical Cancer
Published in International journal of general medicine (31-05-2022)“…Cervical cancer is the fourth most frequent malignancy among women globally, with approximately 604,000 new cases and 341,000 deaths per year. Necroptosis is a…”
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