Search Results - "Yang, Conglian"
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Nanomedicine for acute respiratory distress syndrome: The latest application, targeting strategy, and rational design
Published in Acta pharmaceutica Sinica. B (01-10-2021)“…Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation and destruction of the lung air–blood barrier, leading to irreversible…”
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An injectable bioactive dressing based on platelet-rich plasma and nanoclay: Sustained release of deferoxamine to accelerate chronic wound healing
Published in Acta pharmaceutica Sinica. B (01-10-2023)“…Delayed diabetic wound healing has placed an enormous burden on society. The key factors limiting wound healing include unresolved inflammation and impaired…”
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Enhancing cancer chemo-immunotherapy by biomimetic nanogel with tumor targeting capacity and rapid drug-releasing in tumor microenvironment
Published in Acta pharmaceutica Sinica. B (01-05-2022)“…In the development of chemo-immunotherapy, many efforts have been focusing on designing suitable carriers to realize the co-delivery of chemotherapeutic and…”
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All-in-one approaches for triple-negative breast cancer therapy: metal-phenolic nanoplatform for MR imaging-guided combinational therapy
Published in Journal of nanobiotechnology (12-05-2022)“…Conventional chemotherapy has poor efficacy in triple-negative breast cancer (TNBC) which is highly heterogeneous and aggressive. Imaging-guided therapy is…”
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Radiation-based immunogenic vaccine combined with a macrophage "checkpoint inhibitor" for boosting innate and adaptive immunity against metastatic colon cancers
Published in Acta pharmaceutica Sinica. B (01-05-2024)“…Immunogenic dying tumor cells hold promising prospects as cancer vaccines to activate systemic immunity against both primary and metastatic tumors. Especially,…”
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L-EGCG-Mn nanoparticles as a pH-sensitive MRI contrast agent
Published in Drug delivery (01-01-2021)“…This study aimed to synthesize and characterize L-epigallocatechin gallate (EGCG) complexed Mn 2+ nanoparticle (L-EGCG-Mn), a proof-of-concept pH-sensitive…”
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A magnetic resonance nanoprobe with STING activation character collaborates with platinum-based drug for enhanced tumor immunochemotherapy
Published in Journal of nanobiotechnology (11-12-2021)“…Immunochemotherapy is a potent anti-tumor strategy, however, how to select therapeutic drugs to enhance the combined therapeutic effect still needs to be…”
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Recent Advances in the Application of Vitamin E TPGS for Drug Delivery
Published in Theranostics (2018)“…D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E TPGS or TPGS) has been approved by FDA as a safe adjuvant and widely used in drug delivery systems. The…”
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Intracellularly Generated Immunological Gold Nanoparticles for Combinatorial Photothermal Therapy and Immunotherapy against Tumor
Published in Nano letters (11-09-2019)“…Gold nanoparticle (AuNP) has been widely used in cancer photothermal therapy (PTT) for ablating accessible tumor, while it is insufficient for inhibiting tumor…”
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Bioreactor: Intelligent platform for drug delivery
Published in Nano today (01-06-2022)“…Bioreactor is a system where target substances could be generated through biochemical reaction or bioconversion by utilizing living conditions, including…”
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Extracellular Vesicles Facilitate the Transportation of Nanoparticles within and between Cells for Enhanced Tumor Therapy
Published in ACS applied materials & interfaces (13-09-2023)“…The interaction between nanoparticles and cells is closely associated with the therapeutic effects of nanomedicine. Nanoparticles could be transported among…”
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Reshaping Tumor Immune Microenvironment through Acidity-Responsive Nanoparticles Featured with CRISPR/Cas9-Mediated Programmed Death-Ligand 1 Attenuation and Chemotherapeutics-Induced Immunogenic Cell Death
Published in ACS applied materials & interfaces (08-04-2020)“…Blocking immune checkpoints with monoclonal antibody has been verified to achieve potential clinical successes for cancer immunotherapy. However, its…”
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Transformable Nanoparticle‐Enabled Synergistic Elicitation and Promotion of Immunogenic Cell Death for Triple‐Negative Breast Cancer Immunotherapy
Published in Advanced functional materials (01-11-2019)“…Although cisplatin‐based neoadjuvant chemotherapy is an efficient therapy approach for triple‐negative breast cancer (TNBC), it has dismal prognosis and…”
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Organism‐Generated Biological Vesicles In Situ: An Emerging Drug Delivery Strategy
Published in Advanced science (01-01-2023)“…Biological vesicles, containing genetic materials and proteins of the original cells, are usually used for local or systemic communications among cells…”
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Cell‐Derived Biogenetic Gold Nanoparticles for Sensitizing Radiotherapy and Boosting Immune Response against Cancer
Published in Small (Weinheim an der Bergstrasse, Germany) (01-12-2021)“…The biosynthesis of nanomedicine has gained enormous attention and exhibited promising prospects, while the underlying mechanism and advantage remain not fully…”
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Dying tumor cells-inspired vaccine for boosting humoral and cellular immunity against cancer
Published in Journal of controlled release (01-07-2023)“…Whole tumor cells can act as effective antigen depots and have been regarded as prospective candidate for cancer vaccines. However, the clinical outcomes of…”
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Multifunctional ionic liquids-mediated topical delivery of minoxidil and EGCG for treating androgenic alopecia through promoting angiogenesis and scavenging ROS
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-07-2024)“…[Display omitted] •Multifunctional ionic liquids comprising choline and geranic acid were used innovatively to co-deliver MXD and EGCG for AGA treatment.•Key…”
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Hybrid Biomimetic Nanovesicles to Drive High Lung Biodistribution and Prevent Cytokine Storm for ARDS Treatment
Published in ACS nano (27-09-2022)“…Acute respiratory distress syndrome (ARDS) has been a life threat for patients in ICUs. Vast efforts have been devoted, while no medication has proved viable,…”
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A novel biosynthesized vaccine based on tumor cells for peritoneal metastasis treatment in colon cancer
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-03-2024)“…•Tumor cells could serve as bioreactors for developing therapeutic cancer vaccine.•This immunogenic vaccine possessed adequate antigens and self-generated…”
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