Search Results - "Yang, Chuanzhen"

Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia by Wang, Yuanyuan, Bai, Changsen, Ruan, Yuxia, Liu, Miao, Chu, Qiaoyun, Qiu, Li, Yang, Chuanzhen, Li, Binghui

“…Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine…”
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Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress by Yang, Ronghui, Yang, Chuanzhen, Ma, Lingdi, Zhao, Yiliang, Guo, Zihao, Niu, Jing, Chu, Qiaoyun, Ma, Yingmin, Li, Binghui

“…An enhanced NADH/NAD + ratio, termed reductive stress, is associated with many diseases. However, whether a downstream sensing pathway exists to mediate…”
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A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy by Yang, Chuanzhen, Zang, Weicheng, Tang, Zefang, Ji, Yapeng, Xu, Ruidan, Yang, Yongfeng, Luo, Aiping, Hu, Bin, Zhang, Zemin, Liu, Zhihua, Zheng, Xiaofeng

“…A competent DNA damage response (DDR) helps prevent cancer, but once cancer has arisen, DDR can blunt the efficacy of chemotherapy and radiotherapy that cause…”
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Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation by Ji, Yapeng, Yang, Chuanzhen, Tang, Zefang, Yang, Yongfeng, Tian, Yonglu, Yao, Hongwei, Zhu, Xi, Zhang, Zemin, Ji, Jiafu, Zheng, Xiaofeng

“…Targeting the specific metabolic phenotypes of colorectal cancer stem cells (CRCSCs) is an innovative therapeutic strategy for colorectal cancer (CRC) patients…”
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Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle by Guo, Zihao, Zhang, Yang, Wang, Haoyue, Liao, Liming, Ma, Lingdi, Zhao, Yiliang, Yang, Ronghui, Li, Xuexue, Niu, Jing, Chu, Qiaoyun, Fu, Yanxia, Li, Binghui, Yang, Chuanzhen

“…Protein post-translational modifications (PTMs) are crucial for cancer cells to adapt to hypoxia; however, the functional significance of lysine crotonylation…”
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Effects of coastal saline-alkali soil on rhizosphere microbial community and crop yield of cotton at different growth stages by Feng, Guoyi, Wu, Yajie, Yang, Chuanzhen, Zhang, Qian, Wang, Shulin, Dong, Ming, Wang, Yan, Qi, Hong, Guo, Lixue

“…Soil salinization is a global constraint that significantly hampers agricultural production, with cotton being an important cash crop that is not immune to its…”
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Influence of plant genotype and soil on the cotton rhizosphere microbiome by Yang, Chuanzhen, Yue, Hongchen, Ma, Zheng, Feng, Zili, Feng, Hongjie, Zhao, Lihong, Zhang, Yalin, Deakin, Greg, Xu, Xiangming, Zhu, Heqin, Wei, Feng

“…Rhizosphere microbial communities are recognized as crucial products of intimate interactions between plant and soil, playing important roles in plant growth…”
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Soil bacterial community response to continuous cropping of cotton by Ma, Zheng, Li, Peng, Yang, Chuanzhen, Feng, Zili, Feng, Hongjie, Zhang, Yalin, Zhao, Lihong, Zhou, Jinglong, Zhu, Heqin, Wei, Feng

“…Long-term continuous cropping may result in the outbreak and proliferation of soil-borne diseases, as well as reduction in annual crop production. Overcoming…”
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Compound 968 reverses adriamycin resistance in breast cancer MCF-7ADR cells via inhibiting P-glycoprotein function independently of glutaminase by Yang, Ronghui, Guo, Zihao, Zhao, Yiliang, Ma, Lingdi, Li, Binghui, Yang, Chuanzhen

“…Adriamycin (ADR) is a chemotherapeutic drug widely utilized to treat multiple types of cancers; however, the clinical efficacy of ADR is compromised due to the…”
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SY-1530, a highly selective BTK inhibitor, effectively treats B-cell malignancies by blocking B-cell activation by Wang, Liao, Sun, Yinghui, Liu, Xijie, Li, Hongjuan, Lu, Chang, Yang, Ronghui, Yang, Chuanzhen, Li, Binghui

“…B-cell antigen receptor (BCR) signaling is required to maintain the physiological functions of normal B cells and plays an important pathogenic role in B-cell…”
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Correction: Corrigendum: Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation by Ji, Yapeng, Yang, Chuanzhen, Tang, Zefang, Yang, Yongfeng, Tian, Yonglu, Yao, Hongwei, Zhu, Xi, Zhang, Zemin, Ji, Jiafu, Zheng, Xiaofeng

“…Nature Communications 8: Article number:15308 (2017); Published: 18 May 2017; Updated: 16 June 2017 The original version of this Article contained an error in…”
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The Deubiquitinase USP38 Promotes NHEJ Repair through Regulation of HDAC1 Activity and Regulates Cancer Cell Response to Genotoxic Insults by Yang, Yongfeng, Yang, Chuanzhen, Li, Tingting, Yu, Shuyu, Gan, Tingting, Hu, Jiazhi, Cui, Jun, Zheng, Xiaofeng

“…The DNA damage response (DDR) is essential for maintaining genome integrity. Mounting evidence reveals that protein modifications play vital roles in the DDR…”
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De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence by Yang, Chuanzhen, Zhao, Yiliang, Wang, Liao, Guo, Zihao, Ma, Lingdi, Yang, Ronghui, Wu, Ying, Li, Xuexue, Niu, Jing, Chu, Qiaoyun, Fu, Yanxia, Li, Binghui

“…De novo pyrimidine biosynthesis is achieved by cytosolic carbamoyl-phosphate synthetase II, aspartate transcarbamylase and dihydroorotase (CAD) and uridine…”
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Ribosomal protein L6 (RPL6) is recruited to DNA damage sites in a poly(ADP-ribose) polymerase–dependent manner and regulates the DNA damage response by Yang, Chuanzhen, Zang, Weicheng, Ji, Yapeng, Li, Tingting, Yang, Yongfeng, Zheng, Xiaofeng

“…Ribosomal proteins are the building blocks of ribosome biogenesis. Beyond their known participation in ribosome assembly, the ribosome-independent functions of…”
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Identification of a bacteriophage from an environmental multidrug-resistant E. coli isolate and its function in horizontal transfer of ARGs by Wang, Qiang, Zeng, Xiangpeng, Yang, Qingxiang, Yang, Chuanzhen

“…Horizontal transfer of ARGs was generally considered to be mediated by three methods – transformation, conjugation and transduction through phages – during…”
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Gestational exposure to bisphenol AF causes endocrine disorder of corpus luteum by altering ovarian SIRT-1/Nrf2/NF-kB expressions and macrophage proangiogenic function in mice by Lu, Siying, Liu, Mengling, Liu, Hui, Yang, Chuanzhen, Zhu, Jun, Ling, Yan, Kuang, Haibin

“…Bisphenol AF (BPAF) is extensively used in industrial production as an emerging substitute for the earlier-used bisphenol A (BPA). Studies have found that BPAF…”
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Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis by Zang, Weicheng, Yang, Chuanzhen, Li, Tingting, Liao, Liming, Zheng, Xiaofeng

“…The translesion synthesis (TLS) pathway is a double-edged sword in terms of genome integrity. Deficiency in TLS leads to generation of DNA double strand break…”
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Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth by Liu, Miao, Wang, Yuanyuan, Yang, Chuanzhen, Ruan, Yuxia, Bai, Changsen, Chu, Qiaoyun, Cui, Yanfen, Chen, Ceshi, Ying, Guoguang, Li, Binghui

“…Cancer cells often proliferate under hypoxia and reprogram their metabolism. However, how to find targets to effectively block the hypoxia-associated metabolic…”
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Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition by Chu, Qiaoyun, An, Jing, Liu, Ping, Song, Yihan, Zhai, Xuewei, Yang, Ronghui, Niu, Jing, Yang, Chuanzhen, Li, Binghui

“…Fatty acid uptake is essential for cell physiological function, but detailed mechanisms remain unclear. Here, we generated an acetyl-CoA carboxylases (ACC1/2)…”
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Genetic control of rhizosphere microbiome of the cotton plants under field conditions by Wei, Feng, Feng, Zili, Yang, Chuanzhen, Zhao, Lihong, Zhang, Yalin, Zhou, Jinglong, Feng, Hongjie, Zhu, Heqin, Xu, Xiangming

“…Understanding the extent of heritability of a plant-associated microbiome (phytobiome) is critically important for exploitation of phytobiomes in agriculture…”
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