Search Results - "Yang, Alex J T"

Resveratrol, Metabolic Dysregulation, and Alzheimer's Disease: Considerations for Neurogenerative Disease by Yang, Alex J T, Bagit, Ahmed, MacPherson, Rebecca E K

“…Alzheimer's disease (AD) has traditionally been discussed as a disease where serious cognitive decline is a result of A -plaque accumulation, tau tangle…”
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Influence of metabolic stress and metformin on synaptic protein profile in SH‐SY5Y‐derived neurons by Yang, Alex J. T., Mohammad, Ahmad, Finch, Michael S., Tsiani, Evangelia, Spencer, Gaynor, Necakov, Aleksandar, MacPherson, Rebecca E. K.

“…Insulin resistance (IR) is associated with reductions in neuronal proteins often observed with Alzheimer's disease (AD), however, the mechanisms through which…”
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Chronic AMPK Activation Reduces the Expression and Alters Distribution of Synaptic Proteins in Neuronal SH-SY5Y Cells by Yang, Alex J. T., Mohammad, Ahmad, Tsiani, Evangelia, Necakov, Aleksandar, MacPherson, Rebecca E. K.

“…Neuronal growth and synaptic function are dependent on precise protein production and turnover at the synapse. AMPK-activated protein kinase (AMPK) represents…”
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Acute interleukin-6 modulates key enzymes involved in prefrontal cortex and hippocampal amyloid precursor protein processing by Marko, Daniel M, Finch, Michael S, Yang, Alex J T, Castellani, Laura N, Peppler, Willem T, Wright, David C, MacPherson, Rebecca E K

“…Exercise has been shown to be beneficial for individuals with Alzheimer's disease (AD). In rodent models of AD, exercise decreases the amyloidogenic processing…”
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