Search Results - "Yang, Aifen"
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S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS
Published in Molecular brain (06-10-2021)“…Studies on the development of central nervous system (CNS) primarily rely on the use of specific molecular markers for different types of neural cells. S100B…”
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EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes
Published in Molecular medicine (Cambridge, Mass.) (04-05-2022)“…The conversion of astrocytes activated by nerve injuries to oligodendrocytes is not only beneficial to axonal remyelination, but also helpful for reversal of…”
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3
Differential Inhibition of Sox10 Functions by Notch-Hes Pathway
Published in Cellular and molecular neurobiology (01-05-2020)“…In the developing central nervous system, the terminal differentiation of oligodendrocytes (OLs) is regulated by both extrinsic and intrinsic factors. Recent…”
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Evidence That DDR1 Promotes Oligodendrocyte Differentiation during Development and Myelin Repair after Injury
Published in International journal of molecular sciences (01-06-2023)“…Oligodendrocytes generate myelin sheaths vital for the formation, health, and function of the central nervous system. Mounting evidence suggests that receptor…”
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Stage‐dependent regulation of oligodendrocyte development and enhancement of myelin repair by dominant negative Master‐mind 1 protein
Published in Glia (01-09-2019)“…Notch signaling has been implicated in the inhibition of oligodendrocyte differentiation and myelin gene expression during early development. However,…”
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6
CircXPO1 Promotes Glioblastoma Malignancy by Sponging miR-7-5p
Published in Cells (Basel, Switzerland) (01-03-2023)“…Mounting evidence suggests that circular RNAs play important roles in the development and progression of cancers. However, their function in glioblastomas…”
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Tmeff2 is expressed in differentiating oligodendrocytes but dispensable for their differentiation in vivo
Published in Scientific reports (23-03-2017)“…Myelin elaborated by oligodendrocytes (OLs) in the central nervous system (CNS) is required for saltatory conduction of action potentials along neuronal axons…”
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Chromosomal aberration arises during somatic reprogramming to pluripotent stem cells
Published in Cell division (03-11-2020)“…Abstract Background Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) has opened new therapeutic possibilities. However, karyotypic…”
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Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers
Published in Frontiers in cellular neuroscience (22-09-2021)“…Myelination of neuronal axons in the central nervous system (CNS) by oligodendrocytes (OLs) enables rapid saltatory conductance and axonal integrity, which are…”
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Mitochondrial haplotypes may modulate the phenotypic manifestation of the deafness-associated 12S rRNA 1555A>G mutation
Published in Mitochondrion (01-01-2010)“…Mitochondrial 12S rRNA 1555A>G mutation is one of the important causes of aminoglycoside-induced and nonsyndromic deafness. Our previous investigations showed…”
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TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway
Published in Neuroscience bulletin (01-10-2015)“…Oligodendrocytes(OLs) are glial cells that form myelin sheaths around axons in the central nervous system(CNS).Loss of the myelin sheath in demyelinating and…”
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Mitochondrial tRNAThr G15927A mutation may modulate the phenotypic manifestation of ototoxic 12S rRNA A1555G mutation in four Chinese families
Published in Pharmacogenetics and genomics (01-12-2008)“…OBJECTIVETo investigate the role of mitochondrial modifiers in the development of deafness associated with 12S rRNA A1555G mutation. METHODSFour Chinese…”
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Evolution of the Nervous System Extrapolated from Ctenophore and the Resurrection of Golgi’s Reticular Theory?
Published in Neuroscience bulletin (01-12-2023)Get full text
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ADAMTS4 Enhances Oligodendrocyte Differentiation and Remyelination by Cleaving NG2 Proteoglycan and Attenuating PDGFR α Signaling
Published in The Journal of neuroscience (14-06-2023)“…Although NG2 is known to be selectively expressed in oligodendrocyte precursor cells (OPCs) for many years, its expressional regulation and functional…”
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Mitochondrial ND5 T12338C, tRNACys T5802C, and tRNAThr G15927A variants may have a modifying role in the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese pedigrees
Published in American journal of medical genetics. Part A (15-05-2008)“…We report here on the clinical, genetic, and molecular characterization of three Han Chinese pedigrees with aminoglycoside‐induced and nonsyndromic hearing…”
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Stage‐specific regulation of oligodendrocyte development by Hedgehog signaling in the spinal cord
Published in Glia (01-02-2020)“…Elucidation of signaling pathways that control oligodendrocyte (OL) development is a prerequisite for developing novel strategies for myelin repair in…”
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Aberrant nuclear lamina contributes to the malignancy of human gliomas
Published in Journal of genetics and genomics (01-02-2022)“…Glioma is the most common type of tumor in the central nervous system, accounting for around 80% of all malignant brain tumors. Previous studies showed a…”
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TAPP1 Represses the Differentiation of Oligodendrocyte and its Deficiency Accelerates Myelin Regeneration after Demyelinating Injuries
Published in Neuroscience bulletin (01-03-2021)Get full text
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Genetic Evidence that Dorsal Spinal Oligodendrocyte Progenitor Cells are Capable of Myelinating Ventral Axons Effectively in Mice
Published in Neuroscience bulletin (01-12-2020)“…In the developing spinal cord, the majority of oligodendrocyte progenitor cells (OPCs) are induced in the ventral neuroepithelium under the control of the…”
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AATYK is a Novel Regulator of Oligodendrocyte Differentiation and Myelination
Published in Neuroscience bulletin (01-06-2018)“…Oligodendrocytes (OLs) are myelinating glial cells that form myelin sheaths around axons to ensure rapid and focal conduction of action potentials. Here, we…”
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