Search Results - "Yanez, Diana A."
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DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining
Published in PLoS genetics (01-01-2015)“…Alternative end joining (Alt-EJ) chromosomal break repair involves bypassing classical non-homologous end joining (c-NHEJ), and such repair causes mutations…”
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Journal Article -
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination
Published in Nucleic acids research (08-07-2016)“…We examined the influence of the tetratricopeptide repeat factor XAB2 on chromosomal break repair, and found that XAB2 promotes end resection that generates…”
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Nkx2-5 Suppresses the Proliferation of Atrial Myocytes and Conduction System
Published in Circulation research (28-03-2014)“…RATIONALE:Tight control of cardiomyocyte proliferation is essential for the formation of four-chambered heart. Although human mutation of NKX2-5 is linked to…”
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Journal Article -
4
Human keratinocyte carcinomas have distinct differences in their tumor-associated macrophages
Published in Heliyon (01-08-2019)“…Cutaneous squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) have different clinical behaviors, despite both being keratinocyte carcinomas mainly…”
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The role of macrophages in skin homeostasis
Published in Pflügers Archiv (01-04-2017)“…The skin and its appendages comprise the largest and fastest growing organ in the body. It performs multiple tasks and maintains homeostatic control, including…”
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Journal Article Book Review -
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An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells
Published in Nucleic acids research (08-07-2014)“…The E3 ubiquitin ligase RNF168 is a DNA damage response (DDR) factor that promotes monoubiquitination of H2A/H2AX at K13/15, facilitates recruitment of other…”
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EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele
Published in Nucleic acids research (03-09-2015)“…The maintenance of genome stability is critical for the suppression of diverse human pathologies that include developmental disorders, premature aging,…”
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DNA Damage Response Factors from Diverse Pathways, Including DNA Crosslink Repair, Mediate Alternative End Joining: e1004943
Published in PLoS genetics (01-01-2015)“…Alternative end joining (Alt-EJ) chromosomal break repair involves bypassing classical non-homologous end joining (c-NHEJ), and such repair causes mutations…”
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Journal Article -
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Abstract 171: Nkx2-5 Suppresses The Proliferation Of Atrial Cardiomyocytes And Formation Of The Conduction Cells During Cardiac Development
Published in Circulation research (01-08-2013)“…Abstract only Mutation of human NKX2-5 is linked to atrioventricular conduction abnormalities and atrial septal defects. However, it has been difficult to…”
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Abstract 13: Nkx2-5-notch Signaling Axis Regulates The Proliferation Of The Atrial Myocytes And Conduction System
Published in Circulation research (18-07-2014)“…Abstract only Rationale: Tight control of cardiomyocyte proliferation is essential for the formation of four-chambered heart. Although human mutation of NKX2-5…”
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Journal Article