Search Results - "Yandava, C"

Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype by Cejas, Paloma, Cavazza, Alessia, Yandava, C N, Moreno, Victor, Horst, David, Moreno-Rubio, Juan, Burgos, Emilio, Mendiola, Marta, Taing, Len, Goel, Ajay, Feliu, Jaime, Shivdasani, Ramesh A

“…Cancer cells exhibit dramatic alterations of chromatin organization at cis-regulatory elements, but the molecular basis, extent, and impact of these…”
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Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment by Szczerback, Natalie, Schork, Nicholas, Drazen, Jeffrey M, Drajesk, Jeffrey, Dubé, Louise, Silverman, Eric S, Pillari, Antonino, Yandava, Chandri N, Israel, Elliot, Hippensteel, Richard, Katz, David A

“…Clinically similar asthma patients may develop airway obstruction by different mechanisms. Asthma treatments that specifically interfere with the…”
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Asthma exacerbations during long term β agonist use: influence of β2 adrenoceptor polymorphism by Taylor, D Robin, Drazen, Jeffrey M, Herbison, G Peter, Yandava, Chandra N, Hancox, Robert J, Town, G Ian

“…BACKGROUND Polymorphisms of the β2 adrenoceptor influence receptor function in vitro and asthma phenotypes in vivo. However, their importance in determining…”
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Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription by In, K H, Asano, K, Beier, D, Grobholz, J, Finn, P W, Silverman, E K, Silverman, E S, Collins, T, Fischer, A R, Keith, T P, Serino, K, Kim, S W, De Sanctis, G T, Yandava, C, Pillari, A, Rubin, P, Kemp, J, Israel, E, Busse, W, Ledford, D, Murray, J J, Segal, A, Tinkleman, D, Drazen, J M

“…Five lipoxygenase (5-LO) is the first committed enzyme in the metabolic pathway leading to the synthesis of the leukotrienes. We examined genomic DNA isolated…”
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Association between a sequence variant in the IL-4 gene promoter and FEV1 in asthma by BURCHARD, E. G, SILVERMAN, E. K, DRAZEN, J. M, ROSENWASSER, L. J, BORISH, L, YANDAVA, C, PILLARI, A, WEISS, S. T, HASDAY, J, LILLY, C. M, FORD, J. G

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Asthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphism by Taylor, D R, Drazen, J M, Herbison, G P, Yandava, C N, Hancox, R J, Town, G I

“…Polymorphisms of the beta(2) adrenoceptor influence receptor function in vitro and asthma phenotypes in vivo. However, their importance in determining…”
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The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma by Israel, E, Drazen, J M, Liggett, S B, Boushey, H A, Cherniack, R M, Chinchilli, V M, Cooper, D M, Fahy, J V, Fish, J E, Ford, J G, Kraft, M, Kunselman, S, Lazarus, S C, Lemanske, R F, Martin, R J, McLean, D E, Peters, S P, Silverman, E K, Sorkness, C A, Szefler, S J, Weiss, S T, Yandava, C N

“…Inhaled beta-adrenergic agonists are the most commonly used medications for the treatment of asthma although there is evidence that regular use may produce…”
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A Neuronal NO Synthase (NOS1) Gene Polymorphism Is Associated with Asthma by Grasemann, H., Yandava, C.N., Storm van's Gravesande, K., Deykin, A., Pillari, A., Ma, J., Sonna, L.A., Lilly, C., Stampfer, M.J., Israel, E., Silverman, E.K., Drazen, J.M.

“…Recent family-based studies have revealed evidence for linkage of chromosomal region 12q to both asthma and high total serum immunoglobulin E (IgE) levels…”
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Quantitative trait locus mapping of airway responsiveness to chromosomes 6 and 7 in inbred mice by De Sanctis, G T, Singer, J B, Jiao, A, Yandava, C N, Lee, Y H, Haynes, T C, Lander, E S, Beier, D R, Drazen, J M

“…Quantitative trait locus (QTL) mapping was used to identify chromosomal regions contributing to airway hyperresponsiveness in mice. Airway responsiveness to…”
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Localization of the Gene for Thiamine-Responsive Megaloblastic Anemia Syndrome, on the Long Arm of Chromosome 1, by Homozygosity Mapping by Neufeld, Ellis J., Mandel, Hanna, Raz, Tal, Szargel, Raymonde, Yandava, Chandri N., Stagg, Amy, Fauré, Sabine, Barrett, Timothy, Buist, Neil, Cohen, Nadine

“…Thiamine-responsive megaloblastic anemia, also known as “TRMA” or “Rogers syndrome,” is an early-onset autosomal recessive disorder defined by the occurrence…”
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Association of asthma with beta(2)-adrenergic receptor gene polymorphism and cigarette smoking by Wang, Z, Chen, C, Niu, T, Wu, D, Yang, J, Wang, B, Fang, Z, Yandava, C N, Drazen, J M, Weiss, S T, Xu, X

“…Recent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine…”
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Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma by De Sanctis, G T, MacLean, J A, Hamada, K, Mehta, S, Scott, J A, Jiao, A, Yandava, C N, Kobzik, L, Wolyniec, W W, Fabian, A J, Venugopal, C S, Grasemann, H, Huang, P L, Drazen, J M

“…Asthma is a chronic disease characterized by increased airway responsiveness and airway inflammation. The functional role of nitric oxide (NO) and the various…”
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Exhaled nitric oxide in patients with asthma : Association with NOS1 genotype by WECHSLER, Michael E, GRASEMANN, Hartmut, DEYKIN, Aaron, SILVERMAN, Edwin K, YANDAVA, Chandri N, ISRAEL, Elliot, WAND, Matt, DRAZEN, Jeffrey M

“…An increased concentration of nitric oxide (NO) in exhaled air (FENO) is now recognized as a critical component of the asthmatic phenotype. When we identified…”
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Radiation Hybrid and Cytogenetic Mapping of SOCS1 and SOCS2 to Chromosomes 16p13 and 12q, Respectively by Yandava, C.N., Pillari, A., Drazen, J.M.

“…Suppressor of cytokine signaling (SOCS) proteins are involved in the negative regulation of cytokine-induced STAT (signal transducers and activators of…”
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Polymorphism of the beta(2)-adrenergic receptor gene and desensitization in human airway smooth muscle by Moore, P E, Laporte, J D, Abraham, J H, Schwartzman, I N, Yandava, C N, Silverman, E S, Drazen, J M, Wand, M P, Panettieri, Jr, R A, Shore, S A

“…We examined the influence of two common polymorphic forms of the beta(2)-adrenergic receptor (beta(2)AR): the Gly16 and Glu27 alleles, on acute and long-term…”
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Role for the Epstein-Barr Virus Nuclear Antigen 2 in Viral Promoter Switching During Initial Stages of Infection by WOISETSCHLAEGER, M, JIN, X. W, YANDAVA, C. N, FURMANSKI, L. A, STROMINGER, J. L, SPECK, S. H

“…During latent Epstein-Barr virus (EBV) infection of human B lymphocytes, six viral nuclear antigens (EBNAs) are expressed from long primary transcripts by…”
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Neuronal NO synthase (NOS1) is a major candidate gene for asthma by Grasemann, H, Yandava, C N, Drazen, J M

“…Asthma is a common, but heterogeneous disease, characterized by reversible airway obstruction, bronchial hyperresponsiveness (BHR); and is commonly associated…”
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Pharmacogenetics of the 5-lipoxygenase pathway in asthma by Silverman, E, In, K H, Yandava, C, Drazen, J M

“…It is now well appreciated that asthma is a chronic inflammatory disease of the airways; among the inflammatory cells that have been implicated in the…”
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Cytogenetic and Radiation Hybrid Mapping of Human Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) to Chromosome 13q12 by Yandava, Chandri N., Kennedy, Brian P., Pillari, Anthony, Duncan, Alessandra M., Drazen, J.M.

“…Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is an arachidonic acid binding protein that has been shown to be critical in the biosynthesis of…”
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Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma by Israel, E, Drazen, J M, Liggett, S B, Boushey, H A, Cherniack, R M, Chinchilli, V M, Cooper, D M, Fahy, J V, Fish, J E, Ford, J G, Kraft, M, Kunselman, S, Lazarus, S C, Lemanske, Jr, R F, Martin, R J, McLean, D E, Peters, S P, Silverman, E K, Sorkness, C A, Szefler, S J, Weiss, S T, Yandava, C N

“…Regular use of inhaled beta-adrenergic agonists may have adverse effects in some asthma patients. Polymorphisms of the beta(2)-adrenergic receptor (beta(2)-AR)…”
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