Search Results - "Yanagi, Masaya"
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Dysfunctional Parvalbumin Neurons in Schizophrenia and the Pathway to the Clinical Application of Kv3 Channel Modulators
Published in International journal of molecular sciences (09-08-2024)“…Based on the pathophysiological changes observed in schizophrenia, the gamma-aminobutyric acid (GABA) hypothesis may facilitate the development of targeted…”
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Application of Near-Infrared Spectroscopy for Understanding Spontaneous Brain Activity During Resting State in Schizophrenia: A Mini Review
Published in Frontiers in psychiatry (13-08-2021)“…Spontaneous brain activity occurs at rest, as represented by the default mode network. A resting paradigm is suitable for investigating brain function of…”
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Application of evoked response audiometry for specifying aberrant gamma oscillations in schizophrenia
Published in Scientific reports (07-01-2022)“…Gamma oscillations probed using auditory steady-state response (ASSR) are promising clinical biomarkers that may give rise to novel therapeutic interventions…”
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Evaluating delay of gamma oscillations in patients with schizophrenia using evoked response audiometry system
Published in Scientific reports (05-07-2022)“…Impaired gamma oscillations found in a 40-Hz auditory steady-state response (ASSR) in patients with schizophrenia are the robust findings that can be used for…”
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A decrease in spontaneous activity in medial prefrontal cortex is associated with sustained hallucinations in chronic schizophrenia: An NIRS study
Published in Scientific reports (12-06-2020)“…In functional imaging, accumulating evidence suggests that spontaneous activity decreases during the resting state in the core brain regions of the…”
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Capturing spontaneous activity in the medial prefrontal cortex using near-infrared spectroscopy and its application to schizophrenia
Published in Scientific reports (27-03-2019)“…Near-infrared spectroscopy (NIRS) is an optimal imaging modality used to examine spontaneous brain activity because it can quietly measure blood flow changes…”
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Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors
Published in Molecular psychiatry (01-11-2020)“…Recent findings from in vivo-imaging and human post-mortem tissue studies in schizophrenic psychosis (SzP), have demonstrated functional and molecular changes…”
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Repetition of verbal fluency task attenuates the hemodynamic activation in the left prefrontal cortex: Enhancing the clinical usefulness of near-infrared spectroscopy
Published in PloS one (21-03-2018)“…In applications of near-infrared spectroscopy (NIRS) in clinical psychiatry settings in Japan, a phonemic verbal fluency test (VFT) that includes "switching"…”
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Mitochondrial DNA copy number of peripheral blood in bipolar disorder: The present study and a meta-analysis
Published in Psychiatry research (01-11-2018)“…•Bipolar disorder (BD) had low mitochondrial DNA copy number (mtDNAcn) than controls.•Meta-analysis for all studies showed no association of mtDNAcn alteration…”
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Mitochondrial DNA Copy Number Raises the Potential of Left Frontopolar Hemodynamic Response as a Diagnostic Marker for Distinguishing Bipolar Disorder From Major Depressive Disorder
Published in Frontiers in psychiatry (08-05-2019)“…Given a lack of markers, diagnoses of bipolar disorder (BD) and major depressive disorder (MDD) rely on clinical assessment of symptoms. However, the…”
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Right temporal activation differs between melancholia and nonmelancholic depression: A multichannel near-infrared spectroscopy study
Published in Journal of psychiatric research (01-08-2014)“…Abstract The aim of this study was to determine whether melancholia differs from nonmelancholic depression in frontotemporal functioning by means of…”
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Association of 14-3-3 epsilon gene haplotype with completed suicide in Japanese
Published in Journal of human genetics (01-04-2005)“…Genetic factors have been suggested to be involved in suicide. Although some genetic factors, such as serotonergic transduction, have been associated with…”
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F190. Hippocampal Subfield Activity May Mediate Aspects of Psychosis
Published in Biological psychiatry (1969) (01-05-2018)Get full text
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A putative cis-acting polymorphism in the NOS1 gene is associated with schizophrenia and NOS1 immunoreactivity in the postmortem brain
Published in Schizophrenia research (01-08-2010)“…Abstract Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain elusive. Recent genome-wide scans revealed that rare…”
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Association of calcineurin A gamma subunit ( PPP3CC ) and early growth response 3 ( EGR3 ) gene polymorphisms with susceptibility to schizophrenia in a Japanese population
Published in Psychiatry research (30-01-2011)“…Abstract To examine the association of PPP3CC (rs10108011 and rs2461491) and EGR3 (rs3750192) single-nucleotide polymorphisms (SNPs) with Japanese…”
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Animal models of schizophrenia emphasizing construct validity
Published in Progress in molecular biology and translational science (2012)“…Achieving animal models of schizophrenia which are representative of clear aspects of the illness is critical to understanding pathophysiology and developing…”
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Association of RGS2 Gene Polymorphisms with Suicide and Increased RGS2 Immunoreactivity in the Postmortem Brain of Suicide Victims
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2008)“…Regulators of G-protein signaling are a family of proteins that negatively regulate the intracellular signaling of G protein-coupled receptors, such as the…”
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Expression of Kruppel-like factor 5 gene in human brain and association of the gene with the susceptibility to schizophrenia
Published in Schizophrenia research (01-03-2008)“…Abstract Genome-wide gene expression analysis using DNA microarray technology is a potential tool to search for unexpected genes that have a susceptibility to…”
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Graft schizophrenia
Published in Ryoikibetsu shokogun shirizu (2003)Get more information
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Efficacy of perospirone???paroxetine combination therapy for schizophrenia with obsessive???compulsive disorder
Published in International clinical psychopharmacology (01-07-2006)Get full text
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