Search Results - "Yan, Yuanye"
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Progressive neuroanatomical changes caused by Grin1 loss-of-function mutation
Published in Neurobiology of disease (01-12-2019)“…NMDA receptor dysfunction is central to the encephalopathies caused by missense mutations in the NMDA receptor subunit genes. Missense variants of GRIN1,…”
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CDR1as Deficiency Prevents Photoreceptor Degeneration by Regulating miR-7a-5p/α-syn/Parthanatos Pathway in Retinal Detachment
Published in The American journal of pathology (01-11-2024)Get full text
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The Expression of Parthanatos Markers and miR-7 Mimic Protects Photoreceptors from Parthanatos by Repressing α-Synuclein in Retinal Detachment
Published in The American journal of pathology (01-11-2023)“…Retinal detachment (RD) refers to the separation between the neuroepithelium and the pigment epithelium layer. It is an important disease leading to…”
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Deferiprone protects photoreceptors by inhibiting ferroptosis after experimental retinal detachment
Published in Experimental eye research (14-11-2024)“…The detachment of the retinal neuroepithelium from the retinal pigment epithelium (RPE), often due to a retinal tear and subsequent subretinal fluid (SRF)…”
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Caspase-1 Inhibition Ameliorates Photoreceptor Damage Following Retinal Detachment by Inhibiting Microglial Pyroptosis
Published in The American journal of pathology (01-10-2024)“…Retinal detachment (RD) is a sight-threatening condition that occurs in several retinal diseases. Microglia that reside in retina are activated after RD and…”
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Rapamycin Inhibited Photoreceptor Necroptosis and Protected the Retina by Activation of Autophagy in Experimental Retinal Detachment
Published in Current eye research (03-07-2019)“…Purpose: After experimental retinal detachment (RD), the applications of caspase inhibitor z-vad-fmk (a pan-caspase inhibitor) could inhibit apoptosis, but…”
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TRPML1 Inhibited Photoreceptor Apoptosis and Protected the Retina by Activation of Autophagy in Experimental Retinal Detachment
Published in Ophthalmic research (01-08-2021)“…In this study, we used a rat model of retinal detachment (RD) to investigate the effects of transient receptor potential mucolipin 1 (TRPML1) on photoreceptor…”
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PJ34 Protects Photoreceptors from Cell Death by Inhibiting PARP-1 Induced Parthanatos after Experimental Retinal Detachment
Published in Current eye research (02-01-2021)“…Our previous study discoveredreactive oxygen species (ROS) and apoptosis inducing factor (AIF) increased after retinal detachment. Parthanatos is a cell death…”
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Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants
Published in Neuropsychopharmacology (New York, N.Y.) (26-07-2024)“…Vesicular monoamine transporter 2 (VMAT2) is an essential transporter that regulates brain monoamine transmission and is important for mood, cognition, motor…”
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The Expression of Parthanatos Markers and miR-7a-5p Mimic Protects Photoreceptors from Parthanatos by Repressing α-Synuclein in Retinal Detachment
Published in The American journal of pathology (07-07-2023)“…Retinal detachment (RD) refers to the separation between the neuroepithelium and the pigment epithelium layer. It is an important disease leading to…”
Get full text
Journal Article