Search Results - "Yan, Yongzhao"

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition by Banerjee, Soojay, Bartesaghi, Alberto, Merk, Alan, Rao, Prashant, Bulfer, Stacie L., Yan, Yongzhao, Green, Neal, Mroczkowski, Barbara, Neitz, R. Jeffrey, Wipf, Peter, Falconieri, Veronica, Deshaies, Raymond J., Milne, Jacqueline L. S., Huryn, Donna, Arkin, Michelle, Subramaniam, Sriram

“…p97 is a hexameric AAA+ adenosine triphosphatase (ATPase) that is an attractive target for cancer drug development. We report cryo–electron microscopy…”
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Multi-parameter joint optimization for double-strip high-speed pantographs to improve pantograph-catenary interaction quality by Wu, Mengzhen, Xu, Xianghong, Yan, Yongzhao, Luo, Yi, Huang, Sijun, Wang, Jianshan

“…The significant increase in speed of high-speed train will cause the dynamic contact force of the pantograph-catenary system to fluctuate more severely, which…”
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Large-Scale Solar-Powered UAV Attitude Control Using Deep Reinforcement Learning in Hardware-in-Loop Verification by Yan, Yongzhao, Cao, Huazhen, Zhang, Boyang, Ni, Wenjun, Wang, Bo, Ma, Xiaoping

“…Large-scale solar-powered unmanned aerial vehicles possess the capacity to perform long-term missions at different altitudes from near-ground to near-space,…”
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UAV Swarm Mission Planning and Load Sensitivity Analysis Based on Clustering and Optimization Algorithms by Yan, Yongzhao, Sun, Zhenqian, Hou, Yueqi, Zhang, Boyang, Yuan, Ziwei, Zhang, Guoxin, Wang, Bo, Ma, Xiaoping

“…Unmanned aerial vehicle (UAV) swarms offer unique advantages for area search and environmental monitoring applications. For practical deployments, determining…”
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Structure–Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97 by Alverez, Celeste, Arkin, Michelle R, Bulfer, Stacie L, Colombo, Raffaele, Kovaliov, Marina, LaPorte, Matthew G, Lim, Chaemin, Liang, Mary, Moore, William J, Neitz, R. Jeffrey, Yan, Yongzhao, Yue, Zhizhou, Huryn, Donna M, Wipf, Peter

“…Exploratory SAR studies of a new phenyl indole chemotype for p97 inhibition revealed C-5 indole substituent effects in the ADPGlo assay that did not fully…”
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Enantioselective synthesis and cycloisomerization of 1-bicyclo[1.1.0]butan-1-yl alkylamines by Yan, Yongzhao

“…This dissertation demonstrates the synthesis and application of 1-bicyclo[1.1.0]butyl alkylamines. The enantioselective synthesis of 1-bicyclo[1.1.0]butan-1-yl…”
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Cycloadditions in heterocycle and alkaloid synthesis by Wipf, Peter, Fang, Zhenglai, Ferrié, Laurent, Ueda, Masafumi, Walczak, Maciej A. A., Yan, Yongzhao, Yang, Michael

“…Intramolecular cycloadditions of bicyclo[1.1.0]butylalkyl-amines represent a rich source of novel heterocyclic scaffolds. As a function of the side chain…”
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Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus by Reeve, Stephanie M, Si, Debjani, Krucinska, Jolanta, Yan, Yongzhao, Viswanathan, Kishore, Wang, Siyu, Holt, Graham T, Frenkel, Marcel S, Ojewole, Adegoke A, Estrada, Alexavier, Agabiti, Sherry S, Alverson, Jeremy B, Gibson, Nathan D, Priestley, Nigel D, Wiemer, Andrew J, Donald, Bruce R, Wright, Dennis L

“…The spread of plasmid borne resistance enzymes in clinical Staphylococcus aureus isolates is rendering trimethoprim and iclaprim, both inhibitors of…”
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Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus by Reeve, Stephanie M., Si, Debjani, Krucinska, Jolanta, Yan, Yongzhao, Viswanathan, Kishore, Wang, Siyu, Holt, Graham T., Frenkel, Marcel S., Ojewole, Adegoke A., Estrada, Alexavier, Agabiti, Sherry S., Alverson, Jeremy B., Gibson, Nathan D., Priestly, Nigel D., Wiemer, Andrew J., Donald, Bruce R., Wright, Dennis L.

“…The spread of plasmid borne resistance enzymes in clinical Staphylococcus aureus isolates is rendering trimethoprim and iclaprim, both inhibitors of…”
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