Search Results - "Yan, Yaping"
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Emerging Role of Immunity in Cerebral Small Vessel Disease
Published in Frontiers in immunology (25-01-2018)“…Cerebral small vessel disease (CSVD) is one of the main causes of vascular dementia in older individuals. Apart from risk containment, efforts to prevent or…”
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Immunopathogenesis in Myasthenia Gravis and Neuromyelitis Optica
Published in Frontiers in immunology (12-12-2017)“…Myasthenia gravis (MG) and neuromyelitis optica (NMO) are autoimmune channelopathies of the peripheral neuromuscular junction (NMJ) and central nervous system…”
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The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer's disease: a narrative review
Published in Neural regeneration research (01-12-2023)“…Alzheimer's disease is a neurodegenerative disease that affects a large proportion of older adult people and is characterized by memory loss, progressive…”
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NOTCH2NLC-related repeat expansion disorders: an expanding group of neurodegenerative disorders
Published in Neurological sciences (01-10-2021)“…The NOTCH2NLC gene 5′ untranslated region (UTR) GGC repeat expansion mutations were identified as a genetic contributor of neuronal intranuclear inclusion…”
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Sesamolin Alleviates Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites in High-Fat and High-Fructose Diet-Fed Mice
Published in International journal of molecular sciences (10-11-2022)“…Nonalcoholic fatty liver disease (NAFLD) has become a major public health problem. The effects of sesamolin on obesity-associated NAFLD and its possible…”
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Impact of an immune modulator fingolimod on acute ischemic stroke
Published in Proceedings of the National Academy of Sciences - PNAS (23-12-2014)“…Peripheral lymphocytes entering brain ischemic regions orchestrate inflammatory responses, catalyze tissue death, and worsen clinical outcomes of acute…”
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Sesamin Attenuates Obesity-Associated Nonalcoholic Steatohepatitis in High-Fat and High-Fructose Diet-Fed Mice
Published in Journal of medicinal food (01-03-2023)“…This study explored the effects of sesamin on nonalcoholic steatohepatitis (NASH). High-fat and high-fructose diet-fed mice supplemented with or without…”
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Conformal hexagonal-boron nitride dielectric interface for tungsten diselenide devices with improved mobility and thermal dissipation
Published in Nature communications (13-03-2019)“…Relatively low mobility and thermal conductance create challenges for application of tungsten diselenide (WSe 2 ) in high performance devices. Dielectric…”
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Dysregulated MicroRNA Involvement in Multiple Sclerosis by Induction of T Helper 17 Cell Differentiation
Published in Frontiers in immunology (04-06-2018)“…Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system. Growing evidence has proven that T helper 17 (Th17) cells…”
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Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice
Published in Alzheimer's research & therapy (09-02-2021)“…The neuropathological hallmarks of Alzheimer's disease (AD) are amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs). The amyloid cascade theory is the…”
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Variations of microbial community in Aconitum carmichaeli Debx. rhizosphere soilin a short-term continuous cropping system
Published in The journal of microbiology (01-05-2021)“…Aconitum carmichaeli Debx. (Ranunculaceae) is a potential source of an important herbal drug named “Fuzi”, which is derived from the lateral root of the plant…”
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Altered brain iron depositions from aging to Parkinson's disease and Alzheimer's disease: A quantitative susceptibility mapping study
Published in NeuroImage (Orlando, Fla.) (01-12-2022)“…•Iron deposition significantly increases with aging in many subcortical nuclei, with uneven distribution within nuclei.•In PD, iron is progressively deposited…”
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Structural MRI substrates of cognitive impairment in neuromyelitis optica
Published in Neurology (27-10-2015)“…OBJECTIVE:To identify the clinical and structural MRI markers for predicting cognitive impairment (CI) in patients with neuromyelitis optica (NMO)…”
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Relationship between PIWIL1 gene polymorphisms and epithelial ovarian cancer susceptibility among southern Chinese woman: a three-center case-control study
Published in BMC cancer (27-11-2023)“…To investigate the potential correlation between piwi-like RNA-mediated gene silencing 1 (PIWIL1) polymorphisms and susceptibility to epithelial ovarian cancer…”
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T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
Published in Nature communications (26-07-2022)“…The success of chimeric antigen receptor (CAR) T cells in treating B cell malignancies comes at the price of eradicating normal B cells. Even though T cell…”
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Alteration of the gut microbiota in rhesus monkey with spontaneous osteoarthritis
Published in BMC microbiology (27-11-2021)“…The spontaneous osteoarthritis (OA) in rhesus macaque is similar to OA in human, which maintains an upright body posture and shows very similar biomechanical…”
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Experimental models of neuromyelitis optica: current status, challenges and future directions
Published in Neuroscience bulletin (01-12-2015)“…Neuromyelitis optica (NMO) is a recurrent inflammatory disease that predominantly attacks the optic nerves and spinal cord. NMO-IgG, the specific autoantibody…”
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Spatiotemporal proteomic atlas of multiple brain regions across early fetal to neonatal stages in cynomolgus monkey
Published in Nature communications (03-07-2023)“…Fetal stages are critical periods for brain development. However, the protein molecular signature and dynamics of the human brain remain unclear due to…”
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Perinatal tissue-derived exosomes ameliorate colitis in mice by regulating the Foxp3 + Treg cells and gut microbiota
Published in Stem cell research & therapy (20-03-2023)“…The capacity of self-renewal and multipotent differentiation makes mesenchymal stem cells (MSC) one of the most widely investigated cell lines in preclinical…”
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Presence but not the timing of onset of REM sleep behavior disorder distinguishes evolution patterns in Parkinson's disease
Published in Neurobiology of disease (01-05-2023)“…Rapid eye movement (REM) sleep behavior disorder (RBD) could develop preceding or come after motor symptoms during Parkinson's disease (PD). It remains unknown…”
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