Search Results - "Yan, Xuehan"
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Patient-derived models facilitate precision medicine in liver cancer by remodeling cell-matrix interaction
Published in Frontiers in immunology (04-05-2023)“…Liver cancer is an aggressive tumor originating in the liver with a dismal prognosis. Current evidence suggests that liver cancer is the fifth most prevalent…”
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A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson's disease
Published in Journal of neuroinflammation (22-05-2022)“…The α-synuclein released by neurons activates microglia, which then engulfs α-synuclein for degradation via autophagy. Reactive microglia are a major…”
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Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs–NLRC4 association
Published in European journal of immunology (01-11-2024)“…As cytoplasmic protein complexes that are pivotal for innate immunity, inflammasomes act primarily through the detection of pathogen‐ or danger‐associated…”
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A breakdown in microglial metabolic reprogramming causes internalization dysfunction of [alpha]-synuclein in a mouse model of Parkinson's disease
Published in Journal of neuroinflammation (22-05-2022)“…Background The [alpha]-synuclein released by neurons activates microglia, which then engulfs [alpha]-synuclein for degradation via autophagy. Reactive…”
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Journal Article