Search Results - "Yan, Wanyao"
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USP15 potentiates NF‐κB activation by differentially stabilizing TAB2 and TAB3
Published in The FEBS journal (01-08-2020)“…Tumor necrosis factor α (TNFα)‐ and interleukin 1β (IL‐1β)‐induced nuclear factor‐κB (NF‐κB) activation play key roles in inflammation, immunity, and cancer…”
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ANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ
Published in Nature communications (18-12-2017)“…Excessive nuclear factor-κB (NF-κB) activation mediated by tumor necrosis factor α (TNFα) plays a critical role in inflammation. Here we demonstrate that…”
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Modelling Parkinson's Disease in C. elegans : Strengths and Limitations
Published in Current pharmaceutical design (01-01-2022)“…Parkinson's disease (PD) is a common neurodegenerative disease that affects the motor system and progressively worsens with age. Current treatment options for…”
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Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia
Published in Scientific reports (23-05-2016)“…Aberrant activation of the NOTCH signaling pathway is crucial for the onset and progression of T cell leukemia. Yet recent studies also suggest a tumor…”
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Biological Actions, Implications, and Cautions of Statins Therapy in COVID-19
Published in Frontiers in nutrition (Lausanne) (22-06-2022)“…The Coronavirus Disease 2019 (COVID-19) showed worse prognosis and higher mortality in individuals with obesity. Dyslipidemia is a major link between obesity…”
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NOTCH1 Down-regulates Tumor Suppressor Gene ID4 in T-cell Acute Lymphoblastic Leukemia
Published in Zhongliu fangzhi yanjiu (01-01-2016)“…Objective To explore the expression level of inhibitor of DNA binding 4(ID4) in T-cell acute lymphoblastic leukemia(T-ALL), and to determine the correlation…”
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