Search Results - "Yan, Lianqi"

Functionality of decellularized matrix in cartilage regeneration: A comparison of tissue versus cell sources by Sun, Yu, Yan, Lianqi, Chen, Song, Pei, Ming

“…[Display omitted] Increasing evidence indicates that decellularized extracellular matrices (dECMs) derived from cartilage tissues (T-dECMs) or…”
Get full text

A case of bilateral total knee arthroplasty using different prostheses by Qu, Shanchong, Yan, Lianqi

Get full text

Negative regulation of PI3K/AKT/mTOR axis regulates fibroblast proliferation, apoptosis and autophagy play a vital role in triptolide-induced epidural fibrosis reduction by Dai, Jihang, Sun, Yu, Chen, Duoyun, Zhang, Yaxin, Yan, Lianqi, Li, Xiaolei, Wang, Jingcheng

“…Fibroblasts excessive proliferation was considered as a decisive reason for epidural fibrosis, which was known as a serious complication of lumbar laminectomy…”
Get full text

Treatment of femoral neck fractures: sliding hip screw or cannulated screws? A meta-analysis by Xia, Yutong, Zhang, Wendong, Zhang, Zhen, Wang, Jingcheng, Yan, Lianqi

“…Femoral neck fractures are still unsolved problems nowadays; sliding hip screw (SHS) and cannulated compression screw (CCS) are the most commonly used devices…”
Get full text

Intra-articular injection of decellularized extracellular matrices in the treatment of osteoarthritis in rabbits by Zhang, Yaxin, Dai, Jihang, Yan, Lianqi, Sun, Yu

“…We investigated the role of decellularized cartilage matrix in osteoarthritis to seek a new treatment for this disease. Knee cartilage from rabbits was…”
Get full text

Thermosensitive Hydrogel Loaded with Primary Chondrocyte-Derived Exosomes Promotes Cartilage Repair by Regulating Macrophage Polarization in Osteoarthritis by Sang, Xuehan, Zhao, Xiuhong, Yan, Lianqi, Jin, Xing, Wang, Xin, Wang, Jianjian, Yin, Zhenglu, Zhang, Yuxin, Meng, Zhaoxiang

“…Intra-articular injection is a classic strategy for the treatment of early osteoarthritis (OA). However, the local delivery of traditional therapeutic agents…”
Get more information

Commentary on 'Surface markers associated with chondrogenic potential of human mesenchymal stromal/stem cells' [version 1; peer review: 3 approved] by Lu, Zhihua, Yan, Lianqi, Pei, Ming

“…In the last decade, researchers have searched for predictive surface markers of multipotent mesenchymal stromal/stem cells (MSCs) for ensuring improved…”
Get full text

Melatonin improves mitochondrial function by preventing mitochondrial fission in cadmium-induced rat proximal tubular cell injury via SIRT1–PGC-1α pathway activation by Dong, Wenxuan, Yan, Lianqi, Tan, Yun, Chen, Shufang, Zhang, Kanglei, Gong, Zhonggui, Liu, Wenjing, Zou, Hui, Song, Ruilong, Zhu, Jiaqiao, Liu, Gang, Liu, Zongping

“…Melatonin is an indoleamine produced in the pineal gland and has many physiological roles. There is increasing evidence that melatonin ameliorates cadmium…”
Get full text

Homoharringtonine prevents surgery-induced epidural fibrosis through endoplasmic reticulum stress signaling pathway by Li, Xiaolei, Wang, Shuguang, Dai, Jihang, Yan, Lianqi, Zhao, Shuai, Wang, Jingcheng, Sun, Yu

“…Surgery-induced epidural fibrosis after laminectomy often results in poor clinical outcomes. Fibroblasts proliferation is considered to be one of the major…”
Get full text

Tacrolimus induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-429 and its target of RhoE by Li, Xiaolei, Chen, Hui, Wang, Shuguang, Dai, Jihang, Yan, Lianqi, Wang, Jingcheng, Sun, Yu

“…Tacrolimus (FK506) has been demonstrated to reduce epidural fibrosis. However, the detailed mechanism of action has not been elucidated. Aberrant miR-429 is…”
Get full text

Laminin α5 modulates fibroblast proliferation in epidural fibrosis through the PI3K/AKT/mTOR signaling pathway by Liu, Pengran, Chen, Hui, Yan, Lianqi, Sun, Yu

“…Lumbar laminectomy is commonly deemed as the most valid surgery for a series of lumbar illnesses, such as lumbar disc herniation, which could lead to spinal…”
Get full text

Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE by Sun, Yu, Ge, Yingbin, Fu, Yuxuan, Yan, Lianqi, Cai, Jun, Shi, Kun, Cao, Xiaojian, Lu, Chun

“…Mitomycin C (MMC) is known to reduce epidural fibrosis, but the underlying mechanisms have not yet been elucidated. Aberrant miR-200b expressions have been…”
Get full text

Tamoxifen inhibits fibroblast proliferation and prevents epidural fibrosis by regulating the AKT pathway in rats by Wang, Shuguang, Li, Xiaolei, Yan, Lianqi, Nie, Qian, Dai, Jihang, Chen, Hui, Wang, Jingcheng, Sun, Yu

“…Many factors contribute to epidural fibrosis after lumbar laminectomy, particularly the excessive proliferation of fibroblasts. Many studies have shown that…”
Get full text

Artesunate inhibits fibroblasts proliferation and reduces surgery-induced epidural fibrosis via the autophagy-mediated p53/p21waf1/cip1 pathway by Wan, Qi, Chen, Hui, Li, Xiaolei, Yan, Lianqi, Sun, Yu, Wang, Jingcheng

“…Fibroblast proliferation is considered to be a major cause in the process of epidural fibrosis formation. Autophagy is a tightly-regulated catabolic process in…”
Get full text

Artesunate prevents knee intraarticular adhesion via PRKR-like ER kinase (PERK) signal pathway by Chen, Hui, Tao, Jin, Wang, Jingcheng, Yan, Lianqi

“…Intraarticular scar adhesion refers to a serious complication caused by knee surgery or trauma, leading to various sequelae (e.g., articular cartilage…”
Get full text

Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway by Jiao, Rui, Chen, Hui, Wan, Qi, Zhang, Xiaobo, Dai, Jihang, Li, Xiaolei, Yan, Lianqi, Sun, Yu

“…Failed back surgery syndrome (FBSS) is a common complication after the laminectomy. Epidural fibrosis is the major cause of lower back pain and other…”
Get full text

Hydroxycamptothecin induces apoptosis of fibroblasts and prevents intraarticular scar adhesion in rabbits by activating the IRE-1 signal pathway by Li, Xiaolei, Sun, Yu, Chen, Hui, Zhu, Gengyao, Liang, Yuan, Wang, Qiang, Wang, Jingcheng, Yan, Lianqi

“…Hydroxycamptothecin (HCPT) has been proven to prevent intraarticular scar adhesion, but the mechanism is still unclear. ER stress is known to participate in…”
Get full text

Case report: A 3-year follow-up study of simultaneous bilateral total hip arthroplasty for Femoral head necrosis in a patient with Kashin-Beck Disease by Chen, Xiangyu, Liu, Haibin, Wang, Houqing, Zheng, Liqiang, Li, Jiayu, Yan, Lianqi

“…Introduction Kashin-Beck Disease (KBD) is an endemic disease predominantly affecting joint and skeletal muscle, predisposing the articular cartilage to…”
Get full text

Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis by Sun, Yu, Zhao, Shuai, Li, Xiaolei, Yan, Lianqi, Wang, Jingcheng, Wang, Daxin, Chen, Hui, Dai, Jihang, He, Jun

“…Epidural fibrosis is a common complication after laminectomy. It is associated with intractable lower back pain and additional complications. To date, no study…”
Get full text

Unfavorable Contribution of a Tissue-Engineering Cartilage Graft to Osteochondral Defect Repair in Young Rabbits by Lu, Zhihua, Zhou, Sheng, Vaida, Justin, Gao, Gongming, Stewart, Amanda, Parenti, Joshua, Yan, Lianqi, Pei, Ming

“…A stem cell-based tissue-engineering approach is a promising strategy for treatment of cartilage defects. However, there are conflicting data in the…”
Get full text