Search Results - "Yan, Liang Zeng"

A Novel and Selective β-Melanocyte-Stimulating Hormone-Derived Peptide Agonist for Melanocortin 4 Receptor Potently Decreased Food Intake and Body Weight Gain in Diet-Induced Obese Rats by Hsiung, Hansen M, Hertel, JeAnne, Zhang, Xing-yue, Smith, Dennis P, Smiley, David L, Heiman, Mark L, Yang, Derek D, Husain, Saba, Mayer, John P, Zhang, Lianshan, Mo, Huaping, Yan, Liang Zeng

“…αMSH has generally been accepted as the endogenous ligand for melanocortin 4 receptor (MC4R), which plays a major role in energy homeostasis. Targeting MC4R to…”
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Melanocortin-4 receptor agonists for the treatment of obesity by Emmerson, Paul J, Fisher, Matthew J, Yan, Liang Zeng, Mayer, John P

“…The melanocortin family of receptors (MC 1-5R) and their endogenous peptide ligands (alpha, beta, gamma- MSH and ACTH) have been implicated in the control of a…”
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Use of Trichloroacetimidate Linker in Solid-Phase Peptide Synthesis by Yan, Liang Zeng, Mayer, John P

“…A solid-phase method for the preparation of C-terminal amino-alcohol-containing peptides using activated Wang resin is presented. A diverse set of…”
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Structure-activity relationships of beta-MSH derived melanocortin-4 receptor peptide agonists by Yan, Liang Zeng, Hsiung, Hansen M, Heiman, Mark L, Gadski, Robert A, Emmerson, Paul J, Hertel, JeAnne, Flora, David, Edwards, Patrick, Smiley, Dave, Zhang, Lianshan, Husain, Saba, Kahl, Steven D, DiMarchi, Richard D, Mayer, John P

“…The recent emergence of obesity as a major health threat in the industrialized world has intensified the search for novel and effective pharmacologic…”
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Discovery of a β-MSH-Derived MC-4R Selective Agonist by Mayer, John P, Hsiung, Hansen M, Flora, David B, Edwards, Patrick, Smith, Dennis P, Zhang, Xing-Yue, Gadski, Robert A, Heiman, Mark L, Hertel, JeAnne L, Emmerson, Paul J, Husain, Saba, O'Brien, Thomas P, Kahl, Steven D, Smiley, David L, Zhang, Lianshan, DiMarchi, Richard D, Yan, Liang Zeng

“…A series of novel, disulfide-constrained human β-melanocyte stimulating hormone (β-MSH)-derived peptides were optimized for in vitro melanocortin-4 receptor…”
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Potent peptide agonists for human melanocortin 3 and 4 receptors derived from enzymatic cleavages of human β-MSH(5–22) by dipeptidyl peptidase I and dipeptidyl peptidase IV by Hsiung, Hansen M., Smiley, David L., Zhang, Xing-yue, Zhang, Lianshan, Yan, Liang Zeng, Craft, Libbey, Heiman, Mark L., Smith, Dennis P.

“…Human β-MSH(1–22) was first isolated from human pituitary as a 22-amino acid (aa) peptide derived from a precursor protein, pro-opiomelanocortin (POMC)…”
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Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models by Peng, Sheng-Bin, Zhang, Xiaoyi, Paul, Donald, Kays, Lisa M, Gough, Wendy, Stewart, Julie, Uhlik, Mark T, Chen, Qi, Hui, Yu-Hua, Zamek-Gliszczynski, Maciej J, Wijsman, John A, Credille, Kelly M, Yan, Liang Zeng

“…Emerging evidence demonstrates that stromal cell-derived factor 1 (SDF-1) and CXCR4, a chemokine and chemokine receptor pair, play important roles in…”
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Single-photon detection and its applications by Liang, Yan, Zeng, HePing

“…A single-photon detector is an extremely sensitive device capable of registering photons,offering essential technical support for optics quantum information…”
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Rapid and recurrent neutrophil mobilization regulated by T134, a CXCR4 peptide antagonist by Iyer, Chandrasekar V, Evans, Robert J, Lou, Qinyuan, Lin, Datian, Wang, Jian, Kohn, Wayne, Yan, Liang Zeng, Pulley, Shon, Peng, Sheng-Bin

“…The CXCR4/stromal cell–derived factor-1 (SDF-1) axis plays important roles in development, leukocyte trafficking, HIV infection, and tumorigenesis. Its…”
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Discovery of potent, cyclic calcitonin gene-related peptide receptor antagonists by Yan, Liang Zeng, Johnson, Kirk W., Rothstein, Emily, Flora, David, Edwards, Patrick, Li, Baolin, Li, Junqing, Lynch, Renee, Vaughn, Renee, Clemens-Smith, Amy, McCarty, Deborah, Chow, Charles, McKnight, Kevin L., Lu, Jirong, Nisenbaum, Eric S, Mayer, John P.

“…Calcitonin gene‐related peptide (CGRP), a potent dilator of cerebral and dural vasculature, is known to be elevated in plasma and cerebral spinal fluid during…”
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Novel miniature mobile cardiac catheterization laboratory for critical cardiovascular disease following natural disasters： a feasibility study by Han, Ya-ling, Liang, Zhuo, Yao, Tian-ming, Sun, Jing-yang, Liang, Ming, Huo, Yu, Wang, Geng, Wang, Xiao-zeng, Liang, Yan-chun, Meng, Wei-hong

“…Background Natural disasters have been frequent in recent years. Effective treatment of patients with cardiovascular disease following natural disasters is an…”
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Potent peptide agonists for human melanocortin 3 and 4 receptors derived from enzymatic cleavages of human β-MSH(5-22) by dipeptidyl peptidase i and dipeptidyl peptidase IV: The melanocortin pathway 2005 by HSIUNG, Hansen M, SMILEY, David L, ZHANG, Xing-Yue, LIANSHAN ZHANG, LIANG ZENG YAN, CRAFT, Libbey, HEIMAN, Mark L, SMITH, Dennis P

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Pyramiding blast, bacterial blight and brown planthopper resistance genes in rice restorer lines by JI, Zhi-juan, Yang, Shu-dong, ZENG, Yu-xiang, LIANG, Yan, YANG, Chang-deng, QIAN, Qian

“…Rice blast, bacterial blight （BB） and brown planthopper （BPH） are the three main pests of rice. This study investigated pyr-amiding genes resistant to blast,…”
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Early kidney injury during long-term adefovir dipivoxil therapy for chronic hepatitis B by Jia, Hong-Yu, Ding, Feng, Chen, Jian-Yang, Lian, Jiang-Shan, Zhang, Yi-Min, Zeng, Lin-Yan, Xiang, Dai-Rong, Yu, Liang, Hu, Jian-Hua, Yu, Guo-Dong, Cai, Huan, Lu, Ying-Feng, Zheng, Lin, Li, Lan-Juan, Yang, Yi-Da

“…AIM: To evaluate urine β2-microglobulin(β2-M), retinol-binding protein(RBP) excretion, and renal impairment with adefovir dipivoxil(ADV) for chronic hepatitis…”
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A Water-soluble Conjugated Polymer for Thiol Detection Based on ＂Tu rn-off＂ Effect by Gaoshan Zeng Jie Li Hao Liang Yan Yuan Xiang Li Chao Yin Zhen Yang Quli Fan Xiaomei Lu Wei Huang

“…We investigated a novel water-soluble conjugated polymer （WSCP） for thiol detection based on ＂turn-off＂ ef- fect. This WSCP was modified with poly（ethylene…”
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Preparation and immunogenicity of tag-free recombinant human eppin by Zhang, Jie, Ding, Xin-Liang, Bian, Zeng-Hui, Xia, Yan-Kai, Wang, Shou-Lin, Song, Ling, Wang, Xin-Ru

“…Human epididymal protease inhibitor （eppin） may be effective as a male contraceptive vaccine. In a number of studies, eppin with an engineered His6-tag has…”
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Classification of Infrared Monitor Images of Coal Using an Feature Texture Statistics and Improved BP Network by SUN, Ji-ping, CHEN, Wei, MA, Feng-ying, WANG, Fu-zeng, TANG, Liang, LIU, Yan-jie

“…It is very important to accurately recognize and locate pulverized and block coal seen in a coal mine＇s infrared image monitoring system. Infrared monitor…”
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