Search Results - "Yan, Jinchuan"

Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells by Li, Bo, Zang, Guangyao, Zhong, Wei, Chen, Rui, Zhang, Yue, Yang, Ping, Yan, Jinchuan

“…The schematic diagram for the role of EC-derived exosomes and CD137 signaling on PDGF-BB induced VSMCs phenotype switch by regulating the expression of TET2…”
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The role of TLR4 in pathophysiology of antiphospholipid syndrome‐associated thrombosis and pregnancy morbidity by Xie, Hongxiang, Sheng, Liangju, Zhou, Hong, Yan, Jinchuan

“…Summary The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the clinical features of recurrent thrombosis in the venous or arterial…”
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Role of Macrophages in the Progression and Regression of Vascular Calcification by Li, Yalan, Sun, Zhen, Zhang, Lili, Yan, Jinchuan, Shao, Chen, Jing, Lele, Li, Lihua, Wang, Zhongqun

“…Vascular calcification is an abnormal cell-mediated process in which bone-specific hydroxyapatite crystals are actively deposited on the blood vessel wall and…”
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Effects of thiazolidinedione therapy on inflammatory markers of type 2 diabetes: a meta-analysis of randomized controlled trials by Chen, Rui, Yan, Jinchuan, Liu, Peijing, Wang, Zhongqun

“…Inflammation is a common feature in patients with type 2 diabetes mellitus (T2DM). This meta-analysis aimed to assess the influence of thiazolidinedione (TZD)…”
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Plasminogen activator inhibitor links obesity and thrombotic cerebrovascular diseases: The roles of PAI-1 and obesity on stroke by Chen, Rui, Yan, Jinchuan, Liu, Peijing, Wang, Zhongqun, Wang, Cuiping

“…One of the global socioeconomic phenomena occurred during the last decades is the increased prevalence of obesity, with direct consequence on the risk of…”
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Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway by Chen, Rui, Zhong, Wei, Yin, Runting, Zhang, Yue, Li, Bo, Yan, Jinchuan

“…Combination of antiangiogenesis and immunotherapy may be an effective strategy for treatment of solid tumors. Our previous work reported that activation of…”
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Role of CyPA in cardiac hypertrophy and remodeling by Cao, Mengfei, Yuan, Wei, Peng, Meiling, Mao, Ziqi, Zhao, Qianru, Sun, Xia, Yan, Jinchuan

“…Pathological cardiac hypertrophy is a complex process and eventually develops into heart failure, in which the heart responds to various intrinsic or external…”
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Nε-carboxymethyl-lysine-induced PI3K/Akt signaling inhibition promotes foam cell apoptosis and atherosclerosis progression by Wang, Zhongqun, Bao, Zhengyang, Ding, Yingpeng, Xu, Suining, Du, Rongzeng, Yan, Jinchuan, Li, Lihua, Sun, Zhen, Shao, Chen, Gu, Wen

“…Advanced glycation end products (AGEs) are closely associated with diabetic macrovascular complications. The present study aimed to investigate the effects of…”
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18F-FDG uptake velocity but not uptake level is associated with progression of carotid plaque by Li, Yuefeng, Liang, Yi, Yang, Ping, Xu, Yuhao, Zhang, Ningning, Zhu, Yan, Zhu, Xiaolan, Yan, Jinchuan, Ju, Shenghong

“…Objectives The objective of this study was to evaluate whether baseline 18 F-fluorodeoxyglucose (FDG) uptake is associated with carotid plaque progression…”
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Advanced Glycation End Products Induce Vascular Smooth Muscle Cell-Derived Foam Cell Formation and Transdifferentiate to a Macrophage-Like State by Zhang, Lili, Wang, Xiaodong, Wang, Zhongqun, Jing, Lele, Sun, Zhen, Shao, Chen, Dai, Zhiyin, Yan, Jinchuan, Geng, Yue, Li, Lihua, Bao, Zhengyang, Pang, Qiwen

“…Background. Advanced glycation end products play an important role in diabetic atherosclerosis. The effects of advanced glycation end products (AGEs) on…”
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GW29-e0217 Study of Ghrelin Regulating Calcification in A7r5 Aortic Smooth Muscle Cells Mediated by Osteoprotegerin Signaling by Zhang, Lili, Lihua, Li, Jinchuan, Yan, Zhengyang, Bao, Zhen, Sun, Lele, Jing, Zhongqun, Wang

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The TIR/BB-loop mimetic AS-1 prevents Ang II-induced hypertensive cardiac hypertrophy via NF-κB dependent downregulation of miRNA-143 by Song, Juan, Xie, Qifei, Wang, Lin, Lu, Yi, Liu, Peijing, Yang, Ping, Chen, Rui, Shao, Chen, Qiao, Chen, Wang, Zhongqun, Yan, Jinchuan

“…Untreated pathological cardiac hypertrophy, which can be caused by sustained systemic hypertension, may lead to heart failure. In the present study, we…”
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The Effects of NF-κB and c-Jun/AP-1 on the Expression of Prothrombotic and Proinflammatory Molecules Induced by Anti-β2GPI in Mouse by Xia, Longfei, Xie, Hongxiang, Yu, Yinjing, Zhou, Hong, Wang, Ting, Yan, Jinchuan

“…Our previous data demonstrated that nuclear factor-κB (NF-κB) and activator protein-1 (AP-1) are involved in the process of anti-β2GPI/β2GPI-induced tissue…”
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OX40-OX40L interaction promotes proliferation and activation of lymphocytes via NFATc1 in ApoE-deficient mice by Yan, Jinchuan, Su, Hongling, Xu, Liangjie, Wang, Cuiping

“…Our previous studies have shown that OX40-OX40L interaction regulates the expression of nuclear factor of activated T cells c1(NFATc1) in ApoE(-/-) mice during…”
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A Case of Transcatheter Aortic Valve Replacement for the Treatment of Severe Aortic Stenosis with Multiple Organ Dysfunction by Ma, Jinyu, Wang, Lunping, Chen, Rui, Yan, Jinchuan, Liang, Yi, Liu, Peijing

“…A 77-year-old woman with extremely high risk of mortality due to severe aortic stenosis (AS) and multiple organ failure was admitted to the affiliated hospital…”
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Function of CD147 in Atherosclerosis and Atherothrombosis by Wang, Cuiping, Jin, Rong, Zhu, Xiaolei, Yan, Jinchuan, Li, Guohong

“…CD147, a member of the immunoglobulin super family, is a well-known potent inducer of extracellular matrix metalloproteinases. Studies show that CD147 is…”
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Soluble CD40 ligand stimulates CD40-dependent activation of the β2 integrin Mac-1 and protein kinase C zeda (PKCζ) in neutrophils: implications for neutrophil-platelet interactions and neutrophil oxidative burst by Jin, Rong, Yu, Shiyong, Song, Zifang, Zhu, Xiaolei, Wang, Cuiping, Yan, Jinchuan, Wu, Fusheng, Nanda, Anil, Granger, D Neil, Li, Guohong

“…Recent work has revealed an essential involvement of soluble CD40L (sCD40L) in inflammation and vascular disease. Activated platelets are the major source of…”
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Platelet PI3Kγ Contributes to Carotid Intima-Media Thickening under Severely Reduced Flow Conditions by Wang, Cuiping, Jin, Rong, Nanda, Anil, Yan, Jinchuan, Li, Guohong

“…Studies have begun to focus on the emerging function of platelets as immune and inflammatory cells that initiate and accelerate vascular inflammation…”
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CD137-CD137L interaction regulates atherosclerosis via cyclophilin A in apolipoprotein E-deficient mice by Li, Yuefeng, Yan, Jinchuan, Wu, Chao, Wang, Zhongqun, Yuan, Wei, Wang, Dongqing

“…Our previous studies showed that increased levels of cyclophilin A (CyPA) may be a valuable marker for predicting the severity of acute coronary syndromes and…”
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Involvement of TLR4 in Oxidized LDL/β2GPI/Anti-β2GPI-Induced Transformation of Macrophages to Foam Cells by Zhang, Xiaolei, Xie, Yachao, Zhou, Hong, Xu, Ya, Liu, Jingjing, Xie, Hongxiang, Yan, Jinchuan

“…Aim: It has been reported that oxidized low-density lipoprotein (oxLDL) forms a stable and non-dissociable complex with β2-glycoprotein I (β2GPI) and that IgG…”
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