Search Results - "Yan, Huaqing"
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Genetically identification of endometriosis and cancers risk in women through a two-sample Mendelian randomization study
Published in Scientific reports (10-04-2024)“…Endometriosis is a prevalent and chronic inflammatory gynecologic disorder affecting approximately 6–10% of women globally, and has been associated with an…”
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Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis
Published in World journal of surgical oncology (13-02-2019)“…Because conventional prostate biopsy has some limitations, optimal variations of prostate biopsy strategies have emerged to improve the diagnosis rate of…”
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YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer
Published in Molecular cancer (29-10-2020)“…Background N6-methyladenosine (m.sup.6A) is the most abundant modification in mRNA of humans. Emerging evidence has supported the fact that m.sup.6A is…”
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Identification of m6A suppressor EIF4A3 as a novel cancer prognostic and immunotherapy biomarker through bladder cancer clinical data validation and pan-cancer analysis
Published in Scientific reports (30-09-2023)“…EIF4A3 represents a novel m6A suppressor that exerts control over the global m6A mRNA modification level, therefore influencing gene destiny. Despite…”
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Roles and mechanisms of the m6A reader YTHDC1 in biological processes and diseases
Published in Cell death discovery (02-05-2022)“…N6-methyladenosine (m 6 A) is a key area in Epigenetics and has been increasingly focused these years. In the m 6 A process, readers recognize the m 6 A…”
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Fruit and Vegetable Consumption and the Risk of Prostate Cancer: A Systematic Review and Meta-Analysis
Published in Nutrition and cancer (2022)“…Emerging researches has evaluated whether fruit and vegetable consumption reduce the risk of prostate cancer. However, the conclusions of published articles…”
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The dual role of N6‐methyladenosine modification of RNAs is involved in human cancers
Published in Journal of cellular and molecular medicine (01-10-2018)“…As the most abundant and reversible RNA modification in eukaryotic cells, m6A triggers a new layer of epi‐transcription. M6A modification occurs through a…”
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METTL3/YTHDF2 m6A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer
Published in Journal of cellular and molecular medicine (01-04-2020)“…N6‐Methyladenosine (m6A) modification, the most prevalent modification of eukaryotic messenger RNA (mRNA), is involved in the progression of various tumours…”
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The prognostic and immunological role of MYB: from bladder cancer validation to pan-cancer analysis
Published in Bioscience reports (01-04-2023)“…MYB proto-oncogene is verified as a transcription factor. Although emerging evidence showed that MYB plays a critical part in tumor progression and immunity, a…”
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Dual regulatory role of CCNA2 in modulating CDK6 and MET‐mediated cell‐cycle pathway and EMT progression is blocked by miR‐381‐3p in bladder cancer
Published in The FASEB journal (01-01-2019)“…ABSTRACT Emerging evidence has elucidated that microRNAs (miRNAs) transcribed from miRNA cluster at DLK‐DIO3 imprinted domain are involved in various cancers…”
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MIR-300 in the imprinted DLK1-DIO3 domain suppresses the migration of bladder cancer by regulating the SP1/MMP9 pathway
Published in Cell cycle (Georgetown, Tex.) (17-12-2018)“…Emerging research has suggested that miRNAs play a significant role in oncogenesis and tumor progression by regulating multiple molecular pathways. Here, we…”
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From Cognitive MR-Targeted Fusion Prostate Biopsy to Radical Prostatectomy: Incidence and Predictors of Gleason Grade Group Upgrading in a Chinese Cohort
Published in BioMed research international (17-08-2022)“…Purpose. To access the incidence and predictors of Gleason grade group upgrading from cognitive MR-targeted fusion prostate biopsy to radical prostatectomy in…”
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CCND1, NOP14 and DNMT3B are involved in miR‐502‐5p–mediated inhibition of cell migration and proliferation in bladder cancer
Published in Cell proliferation (01-02-2020)“…Objectives Downregulation of miR‐502‐5p has emerged as a critical factor in tumour progression in several cancers. Herein, we elucidated the role of miR‐502‐5p…”
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The influence of prostate volume on pathological outcomes after radical prostatectomy: A single-center retrospective study
Published in Medicine (Baltimore) (08-12-2023)“…Currently, the association between prostate volume (PV) or prostate weight with pathological outcomes in patients with prostate cancer (PCa) is not well…”
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LncRNA FGF14‐AS2 represses growth of prostate carcinoma cells via modulating miR‐96‐5p/AJAP1 axis
Published in Journal of clinical laboratory analysis (01-11-2021)“…Objective This investigation devoted to lncRNA FGF14 antisense RNA 2 (FGF14‐AS2) in prostate carcinoma progression. Methods The levels of lncRNA FGF14‐AS2,…”
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Roles and mechanisms of the m 6 A reader YTHDC1 in biological processes and diseases
Published in Cell death discovery (02-05-2022)“…N6-methyladenosine (m A) is a key area in Epigenetics and has been increasingly focused these years. In the m A process, readers recognize the m A modification…”
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18
METTL3/YTHDF2 m 6 A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer
Published in Journal of cellular and molecular medicine (01-04-2020)“…N6-Methyladenosine (m A) modification, the most prevalent modification of eukaryotic messenger RNA (mRNA), is involved in the progression of various tumours…”
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CRISPR-ON-Mediated KLF4 overexpression inhibits the proliferation, migration and invasion of urothelial bladder cancer in vitro and in vivo
Published in Oncotarget (24-11-2017)“…Kruppel like factor 4 (KLF4), a transcription factor associated with carcinogenesis and tumor progression, plays an important role in various malignancies. In…”
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Pioglitazone use in patients with diabetes and risk of bladder cancer: a systematic review and meta-analysis
Published in Cancer management and research (01-01-2018)“…Pioglitazone has been reported to increase the risk of bladder cancer but the conclusions of published clinical studies are confusing. We conducted a…”
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