Search Results - "Yan, Guoquan"

GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control by Yang, Yi, Yan, Guoquan, Kong, Siyuan, Wu, Mengxi, Yang, Pengyuan, Cao, Weiqian, Qiao, Liang

“…Large-scale profiling of intact glycopeptides is critical but challenging in glycoproteomics. Data independent acquisition (DIA) is an emerging technology with…”
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Integrated Proteome Analysis Device for Fast Single-Cell Protein Profiling by Shao, Xi, Wang, Xuantang, Guan, Sheng, Lin, Haizhu, Yan, Guoquan, Gao, Mingxia, Deng, Chunhui, Zhang, Xiangmin

“…In our previous work, we have demonstrated an integrated proteome analysis device (iPAD-100) to analyze proteomes from 100 cells. In this work, for the first…”
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Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer by Wu, Di, Hu, Di, Chen, Hao, Shi, Guoming, Fetahu, Irfete S., Wu, Feizhen, Rabidou, Kimberlie, Fang, Rui, Tan, Li, Xu, Shuyun, Liu, Hang, Argueta, Christian, Zhang, Lei, Mao, Fei, Yan, Guoquan, Chen, Jiajia, Dong, Zhaoru, Lv, Ruitu, Xu, Yufei, Wang, Mei, Ye, Yong, Zhang, Shike, Duquette, Danielle, Geng, Songmei, Yin, Clark, Lian, Christine Guo, Murphy, George F., Adler, Gail K., Garg, Rajesh, Lynch, Lydia, Yang, Pengyuan, Li, Yiming, Lan, Fei, Fan, Jia, Shi, Yang, Shi, Yujiang Geno

“…Diabetes is a complex metabolic syndrome that is characterized by prolonged high blood glucose levels and frequently associated with life-threatening…”
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Uncovering missing glycans and unexpected fragments with pGlycoNovo for site-specific glycosylation analysis across species by Zeng, Wen-Feng, Yan, Guoquan, Zhao, Huan-huan, Liu, Chao, Cao, Weiqian

“…Precision mapping of site-specific glycans using mass spectrometry is vital in glycoproteomics. However, the diversity of glycan compositions across species…”
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Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis by Li, Fu-Long, Liu, Jin-Ping, Bao, Ruo-Xuan, Yan, GuoQuan, Feng, Xu, Xu, Yan-Ping, Sun, Yi-Ping, Yan, Weili, Ling, Zhi-Qiang, Xiong, Yue, Guan, Kun-Liang, Yuan, Hai-Xin

“…A bstract Enhanced glycolysis in cancer cells has been linked to cell protection from DNA damaging signals, although the mechanism is largely unknown. The…”
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Highly specific revelation of rat serum glycopeptidome by boronic acid-functionalized mesoporous silica by Liu, Liting, Zhang, Ying, Zhang, Lei, Yan, Guoquan, Yao, Jun, Yang, Pengyuan, Lu, Haojie

“…A highly ordered boronic acid-functionalized mesoporous silica was synthesized and applied for the revelation of rat serum glycopeptidome for the first time…”
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In-Depth Analysis of C Terminomes Based on LysC Digestion and Site-Selective Dimethylation by Du, Xiaoxian, Fang, Caiyun, Yang, Lijun, Bao, Huimin, Zhang, Lei, Yan, Guoquan, Lu, Haojie

“…Analysis of protein C termini is very important for functional annotations of proteomes, while proteome-wide C termini analysis still poses substantial…”
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pGlycoQuant with a deep residual network for quantitative glycoproteomics at intact glycopeptide level by Kong, Siyuan, Gong, Pengyun, Zeng, Wen-Feng, Jiang, Biyun, Hou, Xinhang, Zhang, Yang, Zhao, Huanhuan, Liu, Mingqi, Yan, Guoquan, Zhou, Xinwen, Qiao, Xihua, Wu, Mengxi, Yang, Pengyuan, Liu, Chao, Cao, Weiqian

“…Large-scale intact glycopeptide identification has been advanced by software tools. However, tools for quantitative analysis remain lagging behind, which…”
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Study on behaviors and performances of universal N-glycopeptide enrichment methods by Xue, Yu, Xie, Juanjuan, Fang, Pan, Yao, Jun, Yan, Guoquan, Shen, Huali, Yang, Pengyuan

“…Glycosylation is a crucial process in protein biosynthesis. However, the analysis of glycopeptides through MS remains challenging due to the microheterogeneity…”
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AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis by Wang, Yanan, Luo, Mengjun, Wang, Fan, Tong, Yu, Li, Linfeng, Shu, Yu, Qiao, Ke, Zhang, Lei, Yan, Guoquan, Liu, Jing, Ji, Hongbin, Xie, Youhua, Zhang, Yonglong, Gao, Wei-Qiang, Liu, Yanfeng

“…Tumour cell metabolic plasticity is essential for tumour progression and therapeutic responses, yet the underlying mechanisms remain poorly understood. Here,…”
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Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease by Abudupataer, Mieradilijiang, Zhu, Shichao, Yan, Shiqiang, Xu, Kehua, Zhang, Jingjing, Luo, Shaman, Ma, Wenrui, Alam, Md Fazle, Tang, Yuyi, Huang, Hui, Chen, Nan, Wang, Li, Yan, Guoquan, Li, Jun, Lai, Hao, Wang, Chunsheng, Zhu, Kai, Zhang, Weijia

“…Background: Bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease in general population and is frequently associated with the…”
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vanM, a New Glycopeptide Resistance Gene Cluster Found in Enterococcus faecium by XIAOGANG XU, DONGFANG LIN, JACOBY, George A, MINGGUI WANG, GUOQUAN YAN, XINYU YE, SHI WU, YAN GUO, DEMEI ZHU, FUPIN HU, YINGYUAN ZHANG, FU WANG

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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pGlyco: a pipeline for the identification of intact N-glycopeptides by using HCD- and CID-MS/MS and MS3 by Zeng, Wen-Feng, Liu, Ming-Qi, Zhang, Yang, Wu, Jian-Qiang, Fang, Pan, Peng, Chao, Nie, Aiying, Yan, Guoquan, Cao, Weiqian, Liu, Chao, Chi, Hao, Sun, Rui-Xiang, Wong, Catherine C. L., He, Si-Min, Yang, Pengyuan

“…Confident characterization of the microheterogeneity of protein glycosylation through identification of intact glycopeptides remains one of the toughest…”
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Multifunctional Nanoreactor for Comprehensive Characterization of Membrane Proteins Based on Surface Functionalized Mesoporous Foams by Fang, Xiaoni, Qiao, Liang, Yan, Guoquan, Yang, Pengyuan, Liu, Baohong

“…An integrated protocol is proposed here for efficient analysis of membrane proteins based on surface functionalized mesoporous graphene foams (MGF). The…”
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Discovery and confirmation of O-GlcNAcylated proteins in rat liver mitochondria by combination of mass spectrometry and immunological methods by Cao, Weiqian, Cao, Jing, Huang, Jiangming, Yao, Jun, Yan, Guoquan, Xu, Haoqi, Yang, Pengyuan

“…O-linked β-N-acetylglucosamine (O-GlcNAc) is an important post-translational modification (PTM) consisting of a single N-acetylglucosamine moiety attached via…”
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Circulating proteomic panels for risk stratification of intracranial aneurysm and its rupture by Xiong, Yueting, Zheng, Yongtao, Yan, Yan, Yao, Jun, Liu, Hebin, Shen, Fenglin, Kong, Siyuan, Yang, Shuang, Yan, Guoquan, Zhao, Huanhuan, Zhou, Xinwen, Hu, Jia, Zhou, Bin, Jin, Tao, Shen, Huali, Leng, Bing, Yang, Pengyuan, Liu, Xiaohui

“…The prevalence of intracranial aneurysm (IA) is increasing, and the consequences of its rupture are severe. This study aimed to reveal specific, sensitive, and…”
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Up-regulation of type I collagen during tumorigenesis of colorectal cancer revealed by quantitative proteomic analysis by Zou, Xia, Feng, Bo, Dong, Taotao, Yan, Guoquan, Tan, Binbin, Shen, Hao, Huang, Ao, Zhang, Xiu, Zhang, Menghui, Yang, Pengyuan, Zheng, Minhua, Zhang, Yan

“…Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. The discovery of non-invasive biomarker candidates for diagnosis and prognosis is…”
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Glyco-signatures in patients with advanced lung cancer during anti-PD-1/PD-L1 immunotherapy by Cao, Xinyi, Hu, Zhihuang, Sheng, Xiangying, Sun, Zhenyu, Yang, Lijun, Shu, Hong, Liu, Xiaojing, Yan, Guoquan, Zhang, Lei, Liu, Chao, Zhang, Ying, Wang, Huijie, Lu, Haojie

“…Immune checkpoint inhibitors (ICIs) targeting programmed cell death 1/programmed cell death ligand-1 (PD-1/PD-L1) have significantly prolonged the survival of…”
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Concanavalin A-immobilized magnetic nanoparticles for selective enrichment of glycoproteins and application to glycoproteomics in hepatocelluar carcinoma cell line by Tang, Jia, Liu, Yang, Yin, Peng, Yao, Guoping, Yan, Guoquan, Deng, Chunhui, Zhang, Xiangmin

“…Protein glycosylation is one of the most important PTMs in biological organism. Lectins such as concanavalin A (Con A) have been widely applied to…”
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Comparative Proteomics of Extended-Spectrum Cephalosporin-Resistant Neisseria gonorrhoeae Isolates Demonstrates Altered Protein Synthesis, Metabolism, Substance Transport, and Membrane Permeability by Diao, Nannan, Yan, Guoquan, Yang, Yang, Dong, Yuan, Wang, Ying, Gu, Weiming

“…isolates exhibit resistance to extended-spectrum cephalosporins (ESCs), the last remaining option for first-line empirical monotherapy. Here, we investigated…”
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