Search Results - "Yan, Danfang"
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Chlorogenic Acid, the Main Antioxidant in Coffee, Reduces Radiation-Induced Apoptosis and DNA Damage via NF-E2-Related Factor 2 (Nrf2) Activation in Hepatocellular Carcinoma
Published in Oxidative medicine and cellular longevity (02-08-2022)“…Radiotherapy produces excessive reactive oxygen species (ROS), which can lead to DNA damage and apoptosis in tumor cells, thereby killing malignant cells…”
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2
Prophylactic cranial irradiation in small cell lung cancer: a systematic review and meta-analysis
Published in BMC cancer (21-01-2019)“…The efficacy of prophylactic cranial irradiation (PCI) in treating patients with small cell lung cancer (SCLC) has not been clear, and recent randomized…”
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3
Prognostic Value of a CT Radiomics-Based Nomogram for the Overall Survival of Patients with Nonmetastatic BCLC Stage C Hepatocellular Carcinoma after Stereotactic Body Radiotherapy
Published in Journal of oncology (03-01-2023)“…Purpose. This study aimed to investigatie the feasibility of pretherapeutic CT radiomics-based nomograms to predict the overall survival (OS) of patients with…”
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4
Prognostic and Immunological Potential of Ribonucleotide Reductase Subunits in Liver Cancer
Published in Oxidative medicine and cellular longevity (2023)“…Background. Ribonucleotide reductase (RR) consists of two subunits, the large subunit RRM1 and the small subunit (RRM2 or RRM2B), which is essential for DNA…”
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5
Identification of a RAD51B enhancer variant for susceptibility and progression to glioma
Published in Cancer cell international (19-10-2023)“…Abstract Background RAD51B plays a significant role in homologous recombination-mediated repair of DNA double-strand breaks. Many enhancer variants are…”
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Superior survival for breast-conserving therapy over mastectomy in patients with breast cancer: A population-based SEER database analysis across 30 years
Published in Frontiers in oncology (04-01-2023)“…It has been believed that breast-conserving therapy (lumpectomy plus adjuvant radiation, Lum + RT) and mastectomy without radiation (Mast + NoRT) have…”
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7
Genetic Predisposition to Glioma Mediated by a MAPKAP1 Enhancer Variant
Published in Cellular and molecular neurobiology (01-05-2020)“…Mitogen-activated protein kinase-associated protein 1 (MAPKAP1) is a unique component of the mechanistic target of rapamycin (MTOR) pathway which plays a…”
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Identification of IFN-Induced Transmembrane Protein 1 With Prognostic Value in Pancreatic Cancer Using Network Module-Based Analysis
Published in Frontiers in oncology (22-03-2021)“…Despite improvements reported in diagnosis and treatments in recent decades, pancreatic cancer is still characterized by poor prognosis and low survival rate…”
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9
BreCML: identifying breast cancer cell state in scRNA-seq via machine learning
Published in Frontiers in medicine (06-11-2024)“…Breast cancer is a prevalent malignancy and one of the leading causes of cancer-related mortality among women worldwide. This disease typically manifests…”
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10
The methylation modification of m6A regulators contributes to the prognosis of head and neck squamous cell carcinoma
Published in Annals of translational medicine (01-08-2021)“…N6-methyladenosine (m6A) regulation is a common type of messenger ribonucleic acid (mRNA) modification, and has been proven to contribute to the malignant…”
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11
A novel hydrogel orthotopic injection model in moderately hypofractionated radiation therapy for prostate cancer: Adaptive degradation and durable imaging
Published in Frontiers in oncology (13-01-2023)“…Moderately hypofractionated radiotherapy (MHRT) holds an important position in prostate cancer management. Existing hydrogel spacers can protect the rectum…”
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12
An insertion variant of MGMT disrupts a STAT1 binding site and confers susceptibility to glioma
Published in Cancer cell international (20-09-2021)“…Abstract Background O 6 -methylguanine-DNA methyltransferase (MGMT) is a pivotal enzyme for repairing DNA alkylation damage. Epigenetic modification of MGMT…”
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The Therapeutic Potential of Adipose Tissue-Derived Mesenchymal Stem Cells to Enhance Radiotherapy Effects on Hepatocellular Carcinoma
Published in Frontiers in cell and developmental biology (12-11-2019)“…Several studies have investigated strategies to improve the clinical efficacy of radiotherapy (RT) against hepatocellular carcinoma (HCC), yet the prognosis…”
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Radiotherapy‐Induced Astrocyte Senescence Promotes an Immunosuppressive Microenvironment in Glioblastoma to Facilitate Tumor Regrowth
Published in Advanced science (01-04-2024)“…Accumulating evidence suggests that changes in the tumor microenvironment caused by radiotherapy are closely related to the recurrence of glioma. However, the…”
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An intronic genetic variation of MGMT affects enhancer activity and is associated with glioma susceptibility
Published in Cancer management and research (01-01-2018)“…O -methylguanine-DNA methyltransferase (MGMT) plays a crucial role in repairing damaged DNA caused by alkylating agents. A number of cancer susceptibility loci…”
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Postoperative radiotherapy for glioma: improved delineation of the clinical target volume using the geodesic distance calculation
Published in PloS one (04-06-2014)“…To introduce a new method for generating the clinical target volume (CTV) from gross tumor volume (GTV) using the geodesic distance calculation for glioma. One…”
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Fatal bleeding in a nasopharyngeal carcinoma patient after concurrent chemoradiation plus cetuximab: a case report
Published in OncoTargets and therapy (01-01-2013)“…Carotid blowout syndrome (CBS) refers to the clinical signs and symptoms related to rupture of the carotid artery (CA) and its branches, which mainly results…”
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Osalmid, a Novel Identified RRM2 Inhibitor, Enhances Radiosensitivity of Esophageal Cancer
Published in International journal of radiation oncology, biology, physics (01-12-2020)“…Esophageal cancer (EC) is an aggressive malignancy and is often resistant to currently available therapies. Inhibition of ribonucleotide reductase small…”
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Induction chemotherapy reduces target volume drift in patients with locoregionally advanced nasopharyngeal carcinoma undergoing adaptive intensity-modulated radiotherapy: a retrospective cohort study
Published in Quantitative imaging in medicine and surgery (01-03-2023)“…Adaptive radiotherapy (ART) provides real-time correction of the target and dose of radiation based on repeat computed tomography (CT) imaging and replanning…”
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Analysis of deep inspiration breath-hold technique to improve dosimetric and clinical advantages in postoperative intensity-modulated radiation therapy for thymomas
Published in Quantitative imaging in medicine and surgery (01-08-2022)“…BackgroundRadiation therapy is one of the essential treatment modalities for invasive thymomas. Clinically, respiratory motion poses a challenge for the…”
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