Search Results - "Yamshchikov, G"

Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV‐1 human monoclonal antibody VRC01 in healthy adults by Ledgerwood, J. E., Coates, E. E., Yamshchikov, G., Saunders, J. G., Holman, L., Enama, M. E., DeZure, A., Lynch, R. M., Gordon, I., Plummer, S., Hendel, C. S., Pegu, A., Conan‐Cibotti, M., Sitar, S., Bailer, R. T., Narpala, S., McDermott, A., Louder, M., O'Dell, S., Mohan, S., Pandey, J. P., Schwartz, R. M., Hu, Z., Koup, R. A., Capparelli, E., Mascola, J. R., Graham, B. S.

“…Summary VRC‐HIVMAB060‐00‐AB (VRC01) is a broadly neutralizing HIV‐1 monoclonal antibody (mAb) isolated from the B cells of an HIV‐infected patient. It is…”
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Safety and Immunogenicity of DNA Vaccines Encoding Ebolavirus and Marburgvirus Wild-Type Glycoproteins in a Phase I Clinical Trial by Sarwar, Uzma N., Costner, Pamela, Enama, Mary E., Berkowitz, Nina, Hu, Zonghui, Hendel, Cynthia S., Sitar, Sandra, Plummer, Sarah, Mulangu, Sabue, Bailer, Robert T., Koup, Richard A., Mascola, John R., Nabel, Gary J., Sullivan, Nancy J., Graham, Barney S., Ledgerwood, Julie E.

“…Background. Ebolavirus and Marburgvirus cause severe hemorrhagic fever with high mortality and are potential bioterrorism agents. There are no available…”
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A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults by Ledgerwood, J.E, Costner, P, Desai, N, Holman, L, Enama, M.E, Yamshchikov, G, Mulangu, S, Hu, Z, Andrews, C.A, Sheets, R.A, Koup, R.A, Roederer, M, Bailer, R, Mascola, J.R, Pau, M.G, Sullivan, N.J, Goudsmit, J, Nabel, G.J, Graham, B.S

“…Abstract Ebola virus causes irregular outbreaks of severe hemorrhagic fever in equatorial Africa. Case mortality remains high; there is no effective treatment…”
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Influenza Virus H5 DNA Vaccination Is Immunogenic by Intramuscular and Intradermal Routes in Humans by Ledgerwood, J E, Hu, Z, Gordon, I J, Yamshchikov, G, Enama, M E, Plummer, S, Bailer, R, Pearce, M B, Tumpey, T M, Koup, R A, Mascola, J R, Nabel, G J, Graham, B S

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Contribution of CpG motifs to the immunogenicity of DNA vaccines by Klinman, DM, Yamshchikov, G, Ishigatsubo, Y

“…We previously showed that bacterial DNA contains immunostimulatory motifs consisting of unmethylated CpG dinucleotides flanked by two 5' purines and two 3'…”
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A highly sensitive and versatile virus titration assay in the 96-well microplate format by Borisevich, V., Nistler, R., Hudman, D., Yamshchikov, G., Seregin, A., Yamshchikov, V.

“…This report describes a fast, reproducible, inexpensive and convenient assay system for virus titration in the 96-well format. The micromethod substantially…”
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Protection Against Vaginal SIV Transmission with Microencapsulated Vaccine by Marx, Preston A., Compans, Richard W., Gettie, Agegnehu, Staas, Jay K., Gilley, Richard M., Mulligan, Mark J., Yamshchikov, Galina V., Chen, Dexiang, Eldridge, John H.

“…Although protection in animal models against intravenous challenges with simian immunodeficiency virus (SIV) has been reported, no previous vaccines have…”
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Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27-35) peptide: implications for peptide vaccines by Brinckerhoff, L H, Kalashnikov, V V, Thompson, L W, Yamshchikov, G V, Pierce, R A, Galavotti, H S, Engelhard, V H, Slingluff, Jr, C L

“…Peptide epitopes for tumor-reactive cytotoxic T-lymphocytes (CTL) have been identified on human cancers and are being used in tumor vaccine trials. However,…”
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Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types by Mulligan, M J, Yamshchikov, G V, Ritter, Jr, G D, Gao, F, Jin, M J, Nail, C D, Spies, C P, Hahn, B H, Compans, R W

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evaluation of peptide vaccine immunogenicity in draining lymph nodes and peripheral blood of melanoma patients by Yamshchikov, Galina V., Barnd, Donna L., Eastham, Shannon, Galavotti, Holly, Patterson, James W., Deacon, Donna H., Teates, David, Neese, Patrice, Grosh, William W., Petroni, Gina, Engelhard, Victor H., Slingluff Jr, Craig L.

“…Many peptide epitopes for cytotoxic T lymphocytes (CTLs) have been identified from melanocytic differentiation proteins. Vaccine trials with these peptides…”
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Human immunodeficiency virus type 2 glycoprotein enhancement of particle budding: role of the cytoplasmic domain by Ritter, Jr, G D, Yamshchikov, G, Cohen, S J, Mulligan, M J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Assembly of SIV Virus-like Particles Containing Envelope Proteins Using a Baculovirus Expression System by YAMSHCHIKOV, GALINA V., RITTER, G.DOUGLAS, VEY, MARTIN, COMPANS, RICHARD W.

“…The requirements for SIV particle assembly and envelope incorporation were investigated using a baculovirus expression system. The Pr56gagprecursor protein…”
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Low-dose IL-2 induces cytokine cascade, eosinophilia, and a transient Th2 shift in melanoma patients by CRAGUN, William Chad, YAMSHCHIKOV, Galina V, BISSONETTE, Eric A, SMOLKIN, Mark E, EASTHAM, Shannon, PETRONI, Gina R, SCHRECENGOST, Randy S, WOODSON, Elizabeth M. H, SLINGLUFF, Craig L

“…To assess changes in serum cytokine levels in patients treated concomitantly with or without systemic low-dose IL-2. Vaccination targeted CTL responses to…”
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Human immunodeficiency virus type 2 envelope glycoprotein: differential CD4 interactions of soluble gp120 versus the assembled envelope complex by Mulligan, M J, Ritter, Jr, G D, Chaikin, M A, Yamshchikov, G V, Kumar, P, Hahn, B H, Sweet, R W, Compans, R W

“…Utilizing a recombinant vaccinia expression system, we investigated the biological properties and CD4 receptor interactions of the envelope glycoproteins of a…”
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Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes by Slingluff, Jr, C L, Yamshchikov, G, Neese, P, Galavotti, H, Eastham, S, Engelhard, V H, Kittlesen, D, Deacon, D, Hibbitts, S, Grosh, W W, Petroni, G, Cohen, R, Wiernasz, C, Patterson, J W, Conway, B P, Ross, W G

“…A melanoma vaccine composed of HLA-A2-restricted peptide YLEPGPVTA (gp100(280)), with or without a modified T-helper epitope from tetanus toxoid…”
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Terminal modifications inhibit proteolytic degradation of an immunogenic mart‐127–35 peptide: Implications for peptide vaccines by Brinckerhoff, Laurence H., Kalashnikov, Vladimir V., Thompson, Lee W., Yamshchikov, Galina V., Pierce, Richard A., Galavotti, Holly S., Engelhard, Victor H., Slingluff, Craig L.

“…Peptide epitopes for tumor‐reactive cytotoxic T‐lymphocytes (CTL) have been identified on human cancers and are being used in tumor vaccine trials. However,…”
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Immunogenicity of West Nile virus infectious DNA and its noninfectious derivatives by Seregin, Alexey, Nistler, Ryan, Borisevich, Victoria, Yamshchikov, Galina, Chaporgina, Elena, Kwok, Chun Wai, Yamshchikov, Vladimir

“…The exceptionally high virulence of the West Nile NY99 strain makes its suitability in the development of a live WN vaccine uncertain. The aim of this study is…”
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The suitability of yellow fever and Japanese encephalitis vaccines for immunization against West Nile virus by Yamshchikov, Galina, Borisevich, Victoria, Kwok, Chun Wai, Nistler, Ryan, Kohlmeier, Jake, Seregin, Alexey, Chaporgina, Elena, Benedict, Stephen, Yamshchikov, Vladimir

“…Seven volunteers involved in flavivirus studies have been immunized with commercial Japanese encephalitis and yellow fever vaccines JE-VAX and YF-VAX. Strong…”
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An attenuated West Nile prototype virus is highly immunogenic and protects against the deadly NY99 strain: a candidate for live WN vaccine development by Yamshchikov, Galina, Borisevich, Victoria, Seregin, Alexey, Chaporgina, Elena, Mishina, Margarita, Mishin, Vasiliy, Wai Kwok, Chun, Yamshchikov, Vladimir

“…In a short time, West Nile virus has developed into a nationwide health and veterinary problem. The high virulence of the circulating virus and related lineage…”
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Interleukin-2 Effects Deserve Further Study: A Need for Better Understanding of Biology and of Optimal Dose Regimens by Slingluff, Craig L., Chianese-Bullock, Kim, Yamshchikov, Galina

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