Search Results - "Yamniuk, A."

Fc‐Silent Anti‐CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection by Kim, S. C., Wakwe, W., Higginbotham, L. B., Mathews, D. V., Breeden, C. P., Stephenson, A. C., Jenkins, J., Strobert, E., Price, K., Price, L., Kuhn, R., Wang, H., Yamniuk, A., Suchard, S., Farris, A. B., Pearson, T. C., Larsen, C. P., Ford, M. L., Suri, A., Nadler, S., Adams, A. B.

“…The advent of costimulation blockade provides the prospect for targeted therapy with improved graft survival in transplant patients. Perhaps the most effective…”
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An Anti‐CD154 Domain Antibody Prolongs Graft Survival and Induces Foxp3+ iTreg in the Absence and Presence of CTLA‐4 Ig by Pinelli, D. F., Wagener, M. E., Liu, D., Yamniuk, A., Tamura, J., Grant, S., Larsen, C. P., Suri, A., Nadler, S. G., Ford, M. L.

“…The use of monoclonal antibodies targeting the CD154 molecule remains one of the most effective means of promoting graft tolerance in animal models, but…”
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BMS-986089 is a high affinity anti-myostatin adnectin that increases muscle volume in three preclinical species by Madireddi, M, Malone, H, Kukral, D, Chimalakonda, A, Kozhich, A, Xiling, Y, Swain, J, Yamniuk, A, Ahlijanian, M

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Calmodulin's flexibility allows for promiscuity in its interactions with target proteins and peptides by YAMNIUK, Aaron P, VOGEL, Hans H

“…The small bilobal calcium regulatory protein calmodulin (CaM) activates numerous target enzymes in response to transient changes in intracellular calcium…”
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Structural Investigation into the Differential Target Enzyme Regulation Displayed by Plant Calmodulin Isoforms by Yamniuk, Aaron P, Vogel, Hans J

“…The conserved calmodulin (CaM) isoform SCaM-1 and the divergent SCaM-4 from soybean bind to many of the same target enzymes, but differentially activate or…”
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Structurally Homologous Binding of Plant Calmodulin Isoforms to the Calmodulin-binding Domain of Vacuolar Calcium-ATPase by Yamniuk, Aaron P., Vogel, Hans J.

“…The discovery that plants contain multiple calmodulin (CaM) isoforms having variable sequence identity to mammalian CaM has sparked a flurry of new questions…”
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P.14 - BMS-986089 is a high affinity anti-myostatin adnectin that increases muscle volume in three preclinical species by Madireddi, M., Malone, H., Kukral, D., Chimalakonda, A., Kozhich, A., Xiling, Y., Swain, J., Yamniuk, A., Ahlijanian, M.

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Domain Stability and Metal-Induced Folding of Calcium- and Integrin-Binding Protein 1 by Yamniuk, Aaron P, Silver, Dylan M, Anderson, Kathryn L, Martin, Stephen R, Vogel, Hans J

“…It is widely accepted that a pair of EF-hands is the functional unit of typical four EF-hand proteins such as calmodulin or troponin C. In this work we…”
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MIRG2010 Study: Molecular Interactions in a Three Component System by Bergqvist, S., Doyle, M.L., Edavettal, S.C., Eisenstein, E., Robinson, M.K., Yadav, S.P., Yeung, A.T., Yamniuk, A.

“…r2-2 Protein-protein interactions identified through high-throughput proteomics efforts continue to advance our understanding of the protein interactome; also…”
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MIRG2010 Study: Molecular Interactions in a Three Component System by Bergqvist, S., Edavettal, S., Eisenstein, E., Robinson, M., Yadav, S., Yamniuk, A., Yeung, A., Doyle, M.

“…r2-1 The MIRG 2010 Study was designed to benchmark the capabilities of different laboratories to determine whether two proteins that bind to a common third…”
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Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels by Ishida, Hiroaki, Skorobogatov, Anton, Yamniuk, Aaron P., Vogel, Hans J.

“…Shank proteins are abundant scaffold proteins in the postsynaptic density (PSD) region of brain synapses. Mutations in Shank proteins are associated with…”
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Calcium‐ and magnesium‐dependent interactions between calcium‐ and integrin‐binding protein and the integrin αIIb cytoplasmic domain by Yamniuk, Aaron P., Vogel, Hans J.

“…Calcium‐ and integrin‐binding protein (CIB) is a small EF‐hand calcium‐binding protein that is involved in hemostasis through its interaction with the αIIb…”
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Metal Ion Binding Properties and Conformational States of Calcium- and Integrin-Binding Protein by Yamniuk, Aaron P, Nguyen, Leonard T, Hoang, Tung T, Vogel, Hans J

“…Calcium- and integrin-binding protein (CIB) is a novel member of the helix−loop−helix family of regulatory calcium-binding proteins which likely has a specific…”
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Protein conformational changes studied by diffusion NMR spectroscopy: Application to helix‐loop‐helix calcium binding proteins by Weljie, Aalim M., Yamniuk, Aaron P., Yoshino, Hidenori, Izumi, Yoshinobu, Vogel, Hans J.

“…Pulsed‐field gradient (PFG) diffusion NMR spectroscopy studies were conducted with several helix‐loop‐helix regulatory Ca2+‐binding proteins to characterize…”
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Isotope-labeled vibrational circular dichroism studies of calmodulin and its interactions with ligands by Pandyra, Aleksandra A., Yamniuk, Aaron P., Andrushchenko, Valery V., Wieser, Helmut, Vogel, Hans J.

“…In this work we have studied ligand‐induced secondary structure changes in the small calcium regulatory protein calmodulin (CaM) using vibrational circular…”
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