Search Results - "Yammani, Rama"

PD-L2 Regulates B-1 Cell Antibody Production against Phosphorylcholine through an IL-5-Dependent Mechanism by McKay, Jerome T, Haro, Marcela A, Daly, Christina A, Yammani, Rama D, Pang, Bing, Swords, W Edward, Haas, Karen M

“…B-1 cells produce natural Abs which provide an integral first line of defense against pathogens while also performing important homeostatic housekeeping…”
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Mitigation of doxorubicin-induced cardiotoxicity with an H2O2-Activated, H2S-Donating hybrid prodrug by Hu, Qiwei, Yammani, Rama D., Brown-Harding, Heather, Soto-Pantoja, David R., Poole, Leslie B., Lukesh, John C.

“…Doxorubicin (DOX) is one of the most effective anticancer agents in clinical oncology. Its continued use, however, is severely limited by its dose-dependent…”
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PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism by McKay, Jerome T, Egan, Ryan P, Yammani, Rama D, Chen, Lieping, Shin, Tahiro, Yagita, Hideo, Haas, Karen M

“…Despite the emergence of the programmed cell death 1 (PD-1):PD-1 ligand (PD-L) regulatory axis as a promising target for treating multiple human diseases,…”
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Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens by Yammani, Rama D, Haas, Karen M

“…Ab responses to T cell-independent type 2 (TI-2) Ags, such as bacterial capsular polysaccharides, are critical for host defense. In mice, B-1b cells expressing…”
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Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals by Keyes, Jeremiah D., Parsonage, Derek, Yammani, Rama D., Rogers, LeAnn C., Kesty, Chelsea, Furdui, Cristina M., Nelson, Kimberly J., Poole, Leslie B.

“…ERK-dependent signaling is key to many pathways through which extracellular signals are transduced into cell-fate decisions. One conundrum is the way in which…”
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Structure of the Mid-Region of Tropomyosin: Bending and Binding Sites for Actin by Brown, Jerry H., Zhaocai Zhou, Reshetnikova, Ludmilla, Robinson, Howard, Rama D. Yammani, Tobacman, Larry S., Cohen, Carolyn

“…Tropomyosin is a two-chain α-helical coiled coil whose periodic interactions with the F-actin helix are critical for thin filament stabilization and the…”
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Aging Promotes B-1b Cell Responses to Native, but Not Protein-Conjugated, Pneumococcal Polysaccharides: Implications for Vaccine Protection in Older Adults by Haas, Karen M., Blevins, Maria W., High, Kevin P., Pang, Bing, Swords, W. Edward, Yammani, Rama D.

“…The efficacy of different vaccines in protecting elderly individuals against Streptococcus pneutnoniae infections is not clear. In the current study, aged mice…”
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C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production by Yammani, Rama D, Leyva, Marcela A, Jennings, Ryan N, Haas, Karen M

“…Reductions in C4 levels may predispose individuals to infection with encapsulated bacteria as well as autoimmunity. In this study, we examined the role C4 has…”
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CD8 Marks a Subpopulation of Lung-Derived Dendritic Cells with Differential Responsiveness to Viral Infection and Toll-Like Receptor Stimulation by Beauchamp, Nicole M., Yammani, Rama D., Alexander-Miller, Martha A.

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion by Amoah, Samuel, Holbrook, Beth C, Yammani, Rama D, Alexander-Miller, Martha A

“…Generating and maintaining a robust CD8(+) T cell response in the face of high viral burden is vital for host survival. Further, balancing the differentiation…”
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Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection by Amoah, Samuel, Yammani, Rama D, Grayson, Jason M, Alexander-Miller, Martha A

“…By the peak of the CD8(+) T cell response, the effector cell pool consists of a heterogeneous population of cells that includes both those with an increased…”
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Differentiation-dependent differences in murine T cell susceptibility to negative regulation by the lung by Busick, Rhea Y, Yammani, Rama D, Alexander-Miller, Martha A

“…A large number of viral infections are contracted via the respiratory route. Thus, an effective immune response at this site is of vital importance. Past…”
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In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection by Holbrook, Beth C, Yammani, Rama D, Blevins, Lance K, Alexander-Miller, Martha A

“…Numerous studies have demonstrated a critical role for T cell avidity in predicting in vivo efficacy. Even though the measurement of avidity is now a routine…”
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Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor by Olson, Linda J, Yammani, Rama D, Dahms, Nancy M, Kim, Jung-Ja P

“…The 300 kDa cation‐independent mannose 6‐phosphate receptor (CI‐MPR) mediates the intracellular transport of newly synthesized lysosomal enzymes containing…”
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Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1 by Arimilli, Subhashini, Sharma, Sharad K., Yammani, Rama, Reid, Sean D., Parks, Griffith D., Alexander‐Miller, Martha A.

“…A previously unknown mechanism for the active negative regulation of function in effector T cells is described. CD8+ T cells play a critical role in the…”
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Regulation of maturation and activating potential in CD8+ versus CD8− dendritic cells following in vivo infection with vaccinia virus by Yammani, Rama D, Pejawar-Gaddy, Sharmila, Gurley, Thaddeus C, Weimer, Eric T, Hiltbold, Elizabeth M, Alexander-Miller, Martha A

“…Abstract DC maturation is known to be a necessary step in the generation of an effective immune response. We have used vaccinia virus (VACV) as a model to…”
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Localization of the Carbohydrate Recognition Sites of the Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor to Domains 3 and 9 of the Extracytoplasmic Region by Hancock, Michael K., Yammani, Rama D., Dahms, Nancy M.

“…The insulin-like growth factor II/mannose 6-phosphate receptor is a multifunctional receptor that binds to a diverse array of mannose 6-phosphate (Man-6-P)…”
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Dose-dependent lymphocyte apoptosis following respiratory infection with Vaccinia virus by Yates, Nicole L., Yammani, Rama D., Alexander-Miller, Martha A.

“…Recently there has been renewed interest in poxvirus pathogenesis, especially with regard to infection via the respiratory route. Members of this family are…”
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Abstract P3118: Understanding And Overcoming Doxorubicin-Induced Cardiotoxicity Via Mitochondrial Antioxidants by Farris, Lindsey R, Yammani, Rama D, Poole, Leslie B

“…Chemotherapeutic-induced cardiomyopathies have surpassed cancer as the leading cause of death in patients post-remission. The highly efficacious…”
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Metabolic Stress Induced Modification of Peroxiredoxin 3 and Subsequent Cellular Responses by Farris, Lindsey, Rogers, LeAnn, Parsonage, Derek, Yammani, Rama, Hollis, Thomas, Poole, Leslie

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