Search Results - "Yamazoe, Eriko"
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Dry Powder Inhalers for Proteins Using Cryo-Milled Electrospun Polyvinyl Alcohol Nanofiber Mats
Published in Molecules (Basel, Switzerland) (12-08-2022)“…To enable the efficient delivery of drugs to the lungs, the drug particle design for most dry powder inhalers (DPIs) involves reducing the aerodynamic particle…”
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Controlled Release of Lysozyme Using Polyvinyl Alcohol-Based Polymeric Nanofibers Generated by Electrospinning
Published in Chemical & pharmaceutical bulletin (21-03-2024)“…Polymeric nanofibers generated via electrospinning offer a promising platform for drug delivery systems. This study examines the application of electrospun…”
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Development of Polyvinyl Alcohol (PVA) Nanofibers Containing Cationic Lipid/siRNA Complexes via Electrospinning: The Impact of PVA Characterization
Published in Nanomaterials (Basel, Switzerland) (01-07-2024)“…This study aimed to develop polyvinyl alcohol (PVA) nanofibers encapsulating 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP)/siRNA complexes via…”
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Improving the Powder Properties of an Active Pharmaceutical Ingredient (Ethenzamide) with a Silica Nanoparticle Coating for Direct Compaction into Tablets
Published in Powders (21-11-2022)“…To improve the powder properties of active pharmaceutical ingredients (APIs), we coated APIs with silica nanoparticles using a dry process that allowed for…”
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Cryomilled electrospun nanofiber mats containing d-mannitol exhibit suitable for aerosol delivery of proteins
Published in International journal of pharmaceutics (15-08-2024)“…[Display omitted] •We prepared enzyme inhalation powders by cryomilling electrospun nanofiber mats.•Mannitol increased the friability of nanofiber mats…”
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Design of an oral formulation combining PVA nanofibers and PEGylated liposomes for enhanced drug delivery
Published in Journal of drug delivery science and technology (01-11-2024)“…Modifying the surface properties of nanoparticles is crucial for enhancing the oral absorption of encapsulated drugs. Although both mucoadhesion and mucus…”
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Granulation of ibuprofen/isonicotinamide co-crystals by continuous spray granulator (CTS-SGR)
Published in Advanced powder technology : the international journal of the Society of Powder Technology, Japan (01-07-2023)“…[Display omitted] •We prepared ibuprofen-isonicotinamide co-crystal granules.•The granules were produced directly and continuously by a continuous-spray…”
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Effects of excipient properties on pharmaceutical printlet fabrication via selective laser sintering 3D printing
Published in Advanced powder technology : the international journal of the Society of Powder Technology, Japan (01-11-2024)“…[Display omitted] •The influence of excipients on selective-laser-sintered printlets was investigated.•Various thermoplastic polymers and different grades of…”
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Oral mucus-penetrating PEGylated liposomes to improve drug absorption: Differences in the interaction mechanisms of a mucoadhesive liposome
Published in International journal of pharmaceutics (25-01-2021)“…[Display omitted] We investigated the feasibility of densely polyethylene glycol (PEG2000)-modified liposomes as mucus-penetrating particles (MPPs) for oral…”
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Development of a solid dispersion system for polyvinyl alcohol nanofibers embedded with silicon dioxide particles via emulsion electrospinning for improved solubility of poorly water-soluble drugs
Published in Journal of drug delivery science and technology (01-09-2024)“…This study explored the development of solid dispersions of probucol (PBC), a poorly water-soluble drug, embedded within polyvinyl alcohol (PVA) nanofibers at…”
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Intranasal administration of liposomes: Potential brain delivery with prospective ophthalmic reach
Published in Journal of drug delivery science and technology (01-11-2024)“…The low efficacy of drug transportation from the bloodstream to specific tissues remains a challenge in drug delivery to the central nervous system (CNS),…”
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