Search Results - "Yamazaki, Tomohiro"

Control of condensates dictates nucleolar architecture by Yamazaki, Tomohiro, Hirose, Tetsuro

“…Long noncoding RNA directs biophysical properties of phase-separated nucleoli Intracellular organelles that lack a membrane boundary are often formed through…”
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Molecular anatomy of the architectural NEAT1 noncoding RNA: The domains, interactors, and biogenesis pathway required to build phase‐separated nuclear paraspeckles by Hirose, Tetsuro, Yamazaki, Tomohiro, Nakagawa, Shinichi

“…Long noncoding RNAs (lncRNAs) are extremely diverse and have various significant physiological functions. lncRNAs generally associate with specific sets of…”
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Molecular dissection of nuclear paraspeckles: towards understanding the emerging world of the RNP milieu by Nakagawa, Shinichi, Yamazaki, Tomohiro, Hirose, Tetsuro

“…Paraspeckles are nuclear bodies built on an architectural long noncoding RNA, NEAT1, and a series of studies have revealed their molecular components, fine…”
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Unusual semi‐extractability as a hallmark of nuclear body‐associated architectural noncoding RNAs by Chujo, Takeshi, Yamazaki, Tomohiro, Kawaguchi, Tetsuya, Kurosaka, Satoshi, Takumi, Toru, Nakagawa, Shinichi, Hirose, Tetsuro

“…NEAT1_2 long noncoding RNA (lncRNA) is the molecular scaffold of paraspeckle nuclear bodies. Here, we report an improved RNA extraction method: extensive…”
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Architectural RNAs for Membraneless Nuclear Body Formation by Yamazaki, Tomohiro, Nakagawa, Shinichi, Hirose, Tetsuro

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Phase separation driven by production of architectural RNA transcripts by Yamamoto, Tetsuya, Yamazaki, Tomohiro, Hirose, Tetsuro

“…We here use an extension of the Flory-Huggins theory to predict that phase separation is driven by the production of architectural RNA (arcRNA) at a DNA locus…”
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ArcRNAs and the formation of nuclear bodies by Nakagawa, Shinichi, Yamazaki, Tomohiro, Mannen, Taro, Hirose, Tetsuro

“…Long noncoding RNAs (lncRNAs) have long been collectively and passively defined as transcripts that do not encode proteins. However, extensive functional…”
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Characterization of Actin-based Genotypes and Mycoplasma Endosymbionts of Trichomonas vaginalis Isolated in Sapporo, Japan by Yamazaki, Tomohiro, Sawai, Kyohei, Takahashi, Yuji, Matsuo, Junji

“…Purpose Trichomonas vaginali s is a causative agent of common non-viral sexually transmitted infections worldwide. However, the biological features, such as…”
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Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition by Modic, Miha, Grosch, Markus, Rot, Gregor, Schirge, Silvia, Lepko, Tjasa, Yamazaki, Tomohiro, Lee, Flora C.Y., Rusha, Ejona, Shaposhnikov, Dmitry, Palo, Michael, Merl-Pham, Juliane, Cacchiarelli, Davide, Rogelj, Boris, Hauck, Stefanie M., von Mering, Christian, Meissner, Alexander, Lickert, Heiko, Hirose, Tetsuro, Ule, Jernej, Drukker, Micha

“…RNA-binding proteins (RBPs) and long non-coding RNAs (lncRNAs) are key regulators of gene expression, but their joint functions in coordinating cell fate…”
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Massive-mode polarization entangled biphoton frequency comb by Yamazaki, Tomohiro, Ikuta, Rikizo, Kobayashi, Toshiki, Miki, Shigehito, China, Fumihiro, Terai, Hirotaka, Imoto, Nobuyuki, Yamamoto, Takashi

“…A frequency-multiplexed entangled photon pair and a high-dimensional hyperentangled photon pair are useful to realize a high-capacity quantum communication. A…”
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Remarkable improvement in detection of readthrough downstream-of-gene transcripts by semi-extractable RNA-sequencing by Iwakiri, Junichi, Tanaka, Kumiko, Chujo, Takeshi, Takakuwa, Hiro, Yamazaki, Tomohiro, Terai, Goro, Asai, Kiyoshi, Hirose, Tetsuro

“…The mammalian cell nucleus contains dozens of membrane-less nuclear bodies that play significant roles in various aspects of gene expression. Several nuclear…”
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Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter by Nishito, Yukina, Tsuji, Natsuko, Fujishiro, Hitomi, Takeda, Taka-aki, Yamazaki, Tomohiro, Teranishi, Fumie, Okazaki, Fumiko, Matsunaga, Ayu, Tuschl, Karin, Rao, Rajini, Kono, Satoshi, Miyajima, Hiroaki, Narita, Hiroshi, Himeno, Seiichiro, Kambe, Taiho

“…Manganese homeostasis involves coordinated regulation of specific proteins involved in manganese influx and efflux. However, the proteins that are involved in…”
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Dynamic compensation robot with a new high-speed vision system for flexible manufacturing by Huang, Shouren, Shinya, Kenta, Bergström, Niklas, Yamakawa, Yuji, Yamazaki, Tomohiro, Ishikawa, Masatoshi

“…This paper aims to enable an industrial robot to realize real-time adaptation to uncertainty, which is generally associated with the issue of machine…”
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Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus by Yamamoto, Tetsuya, Yamazaki, Tomohiro, Ninomiya, Kensuke, Hirose, Tetsuro

“…Liquid-liquid phase separation (LLPS) has been thought to be the biophysical principle governing the assembly of the multiphase structures of nucleoli, the…”
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U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish by Yu, Yong, Chi, Binkai, Xia, Wei, Gangopadhyay, Jaya, Yamazaki, Tomohiro, Winkelbauer-Hurt, Marlene E, Yin, Shanye, Eliasse, Yoan, Adams, Edward, Shaw, Christopher E, Reed, Robin

“…Mutations in FUS cause amyotrophic lateral sclerosis (ALS), but the molecular pathways leading to neurodegeneration remain obscure. We previously found that U1…”
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Triblock copolymer micelle model of spherical paraspeckles by Yamamoto, Tetsuya, Yamazaki, Tomohiro, Hirose, Tetsuro

“…Paraspeckles are nuclear bodies scaffolded by RNP complexes of NEAT1_2 RNA transcripts and multiple RNA-binding proteins. The assembly of paraspeckles is…”
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Utility of contrast‐enhanced harmonic endoscopic ultrasonography for predicting the prognosis of pancreatic neuroendocrine neoplasms by Ishikawa, Rei, Kamata, Ken, Hara, Akane, Tanaka, Hidekazu, Okamoto, Ayana, Yamazaki, Tomohiro, Nakai, Atsushi, Omoto, Shunsuke, Minaga, Kosuke, Yamao, Kentaro, Takenaka, Mamoru, Minami, Yasunori, Watanabe, Tomohiro, Chiba, Yasutaka, Chikugo, Takaaki, Matsumoto, Ippei, Takeyama, Yoshifumfi, Matsukubo, Yuko, Hyodo, Tomoko, Kudo, Masatoshi

“…Background and Aims Pancreatic neuroendocrine neoplasms (PanNENs), including Grade 1 (G1) or G2 tumors, can have a poor prognosis. This study investigated the…”
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Micellization: A new principle in the formation of biomolecular condensates by Yamazaki, Tomohiro, Yamamoto, Tetsuya, Hirose, Tetsuro

“…Phase separation is a fundamental mechanism for compartmentalization in cells and leads to the formation of biomolecular condensates, generally containing…”
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Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes by Fujita, Ken-ichi, Ito, Misa, Irie, Midori, Harada, Kotaro, Fujiwara, Naoko, Ikeda, Yuya, Yoshioka, Hanae, Yamazaki, Tomohiro, Kojima, Masaki, Mikami, Bunzo, Mayeda, Akila, Masuda, Seiji

“…mRNA export is an essential pathway for the regulation of gene expression. In humans, closely related RNA helicases, UAP56 and URH49, shape selective mRNA…”
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Comparison of radiation exposure between endoscopic ultrasound‐guided drainage and transpapillary drainage by endoscopic retrograde cholangiopancreatography for pancreatobiliary diseases by Takenaka, Mamoru, Hosono, Makoto, Rehani, Madan M., Chiba, Yasutaka, Ishikawa, Rei, Okamoto, Ayana, Yamazaki, Tomohiro, Nakai, Atsushi, Omoto, Shunsuke, Minaga, Kosuke, Kamata, Ken, Yamao, Kentaro, Hayashi, Shiro, Nishida, Tsutomu, Kudo, Masatoshi

“…Objectives The transpapillary drainage by endoscopic retrograde cholangiopancreatography (ERCP‐D) cannot be performed without fluoroscopy, and there are many…”
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