Search Results - "Yamazaki, Masaki"
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1
Three-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments
Published in Scientific reports (21-02-2020)“…Colorectal cancer demonstrates intra-tumour heterogeneity formed by a hierarchical structure comprised of cancer stem cells (CSCs) and their differentiated…”
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2
Histopathological evaluation of crypt fission during intestinal development in neonatal mice
Published in Journal of Toxicologic Pathology (01-01-2020)“…Pathological evaluation of juvenile toxicity studies requires the understanding of normal tissue development at different ages. Here, we report the…”
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3
Robots traveling on muddy terrain for sampling bottom sediment in tidal flats
Published in Artificial life and robotics (01-02-2024)“…The purpose of this research is to develop robots that perform mud sampling on tidal flats automatically. Erosions that occur on beaches and sands go away to…”
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4
Lipomatosis of axillary lymph nodes in a cynomolgus monkey (Macaca fascicularis)
Published in Journal of Toxicologic Pathology (01-01-2022)“…Lipomatosis of lymph nodes is defined as the replacement of the lymphatic parenchyma by adipose tissue which grows in the node from the hilus toward the…”
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5
A simple method for histopathological evaluation of organoids
Published in Journal of Toxicologic Pathology (01-01-2018)“…In vitro-cultured 3D structures called organoids have become important tools for biological research, but there is little information concerning simple and…”
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6
Continuous formation of small clusters with LGR5-positive cells contributes to tumor growth in a colorectal cancer xenograft model
Published in Laboratory investigation (01-01-2021)“…New cancer characteristics can be discovered by focusing on the process of tumor formation. Cancer stem cells (CSCs) are a key subpopulation, as they are…”
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7
Exploring the fluorescence quenching interaction of amino acids and protein with natural organic matter by a multi-spectroscopic method
Published in Water science & technology. Water supply (01-11-2021)“…Abstract The main objective of this research was to explore the fluorescence quenching mechanism of a humic substance (Suwannee River natural organic matter…”
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8
Myocardial injury in a patient with severe coronavirus disease: A case report
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-02-2021)“…Coronavirus disease (COVID-19) can lead to severe disease or death and is characterized by a wide range of mild to severe symptoms. In addition to the lungs,…”
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9
PAXgene-fixed paraffin-embedded sample is applicable to laser capture microdissection with well-balanced RNA quality and tissue morphology
Published in Journal of Toxicologic Pathology (01-01-2018)“…Assessing how gene expression analysis by RNA sequencing (RNA-Seq) correlates to a unique morphology is increasingly necessary, and laser capture…”
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10
Digital workflows for pathological assessment of rat estrous cycle stage using images of uterine horn and vaginal tissue
Published in Journal of pathology informatics (01-01-2022)“…Assessment of the estrous cycle of mature female mammals is an important component of verifying the efficacy and safety of drug candidates. The common…”
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11
Intensive Immunofluorescence Staining Methods for Low Expression Protein: Detection of Intestinal Stem Cell Marker LGR5
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (29-10-2015)“…Leucine-rich repeat-containing G-protein coupled receptor 5, or LGR5, is a molecule that recognizes stem cells in multiple organs and also in colon cancer…”
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12
IL-6R distribution in normal human and cynomolgus monkey tissues
Published in Regulatory toxicology and pharmacology (01-02-2009)“…Interleukin-6 (IL-6) is a pleiotropic cytokine and a contributing factor in many diseases such as rheumatoid arthritis, Castleman’s disease, Crohn’s disease,…”
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13
Cell proliferative activity in the kidney of young growing rat analyzed using flash and cumulative labeling with bromodeoxyuridine
Published in Journal of toxicological sciences (01-10-2010)“…We examined the cell proliferation activity of kidney in young growing rats using flash and cumulative labeling with bromodeoxyuridine (BrdU). Rats were…”
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14
Segmentation of the Pathophysiological Stages of Diabetic Changes in the db/db Mouse
Published in Journal of Toxicologic Pathology (01-01-2009)“…The db/db mouse is one of the diabetes mellitus animal models and if the pathophysiological stages of diabetic changes in the mouse model could simulate the…”
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15
PAXgene-fixed paraffin-embedded sample is applicable to laser capture microdissection with well-balanced RNA quality and tissue morphology
Published in Journal of Toxicologic Pathology (2018)“…[Abstract :] Assessing how gene expression analysis by RNA sequencing (RNA-Seq) correlates to a unique morphology is increasingly necessary, and laser capture…”
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16
Multi-Scale Weight Sharing Network for Image Recognition
Published in Pattern recognition letters (01-03-2020)“…•We explore the idea of weight sharing over multiple scales in convolutional networks.•We evaluate on two of the largest image recognition datasets (ImageNet…”
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17
Molecular mechanism on the testicular toxicity of 1,3-dinitrobenzene in Sprague-Dawley rats : preliminary study
Published in Archives of toxicology (01-12-2005)“…The present study was conducted to elucidate the possible molecular mechanism of germinal cell apoptosis induced by Sertoli cell damage after…”
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18
Differences in bone responses to recombinant human granulocyte colony-stimulating factor between mice and rats
Published in Journal of toxicological sciences (01-05-2008)“…The authors previously demonstrated that high doses of recombinant human granulocyte colony-stimulating factor (rhG-CSF) induce bone changes characterized by…”
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19
Granulocyte colony-stimulating factor has no adverse effects on atherosclerotic lesions in high cholesterol-fed miniature swine
Published in Journal of Veterinary Medical Science (01-09-2008)“…Granulocyte colony-stimulating factor (G-CSF) is widely used to mobilize peripheral blood stem cells, and expected to restore cardiac function for patients…”
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20
Protruding structures with high expression of LGR5 are formed during regrowth phase after chemo-treatment in xenograft model of colorectal adenocarcinoma
Published in Histology and histopathology (01-01-2022)“…Recurrence after chemotherapy is one of the biggest obstacles in cancer therapy, along with metastasis. Although histopathological evaluation in preclinical…”
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