Search Results - "Yamauchi, Keishi"
-
1
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes
Published in Endocrine Journal (2013)“…Aim of the study was to clarify the relationship between metformin-induced vitamin B12 (B12) deficiency, hyperhomocysteinemia and vascular complications in…”
Get full text
Journal Article -
2
Impact of impaired insulin secretion and insulin resistance on the incidence of diabetes in a Japanese cohort
Published in Diabetologia (01-11-2013)Get full text
Journal Article -
3
Pharmacokinetics of insulin disappearance after massive overdosing
Published in ENDOCRINE JOURNAL (01-01-2018)“…Long-term glucose supplementation is required to prevent hypoglycemia after massive insulin overdosing. We fitted the blood insulin concentration-time profile…”
Get full text
Journal Article -
4
Development of new diabetes risk scores on the basis of the current definition of diabetes in Japanese subjects [Rapid Communication]
Published in ENDOCRINE JOURNAL (01-01-2016)“…To develop diabetes risk score (RS) based on the current definition of diabetes, we retrospectively analyzed consecutive 4,159 health examinees who were…”
Get full text
Journal Article -
5
Impact of one-hour postchallenge glucose on the relationship between insulin sensitivity and secretion
Published in ENDOCRINE JOURNAL (2015)“…The impact of postchallenge glucose on the relationship between insulin sensitivity (SI) and secretion (β) is unknown. We analyzed data from 2,264 health…”
Get full text
Journal Article -
6
The evolution of non-diabetic hyperglycemia: a longitudinal study
Published in ENDOCRINE JOURNAL (01-01-2014)“…The risk factors for impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) have yet to be established. Our aim was to elucidate the predisposing…”
Get full text
Journal Article -
7
798-P: Luseogliflozin Suppresses Fine Glycemic Fluctuation Late at Night: New Aspect of SGLT2 Inhibitor
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Sodium-glucose cotransporter 2 (SGLT2) inhibitors block reabsorption of glucose by inhibiting SGLT2 in kidney, promotes the renal excretion of glucose. They…”
Get full text
Journal Article -
8
Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism
Published in Endocrine Journal (2016)“…A 43-yr-old hypertensive male was admitted due to hypokalemia (1.8 mEq/L) and renal dysfunction (eGFR, 20.0 mL/min/1.73 m2). His plasma aldosterone was 901.0…”
Get full text
Journal Article -
9
Longitudinal changes in insulin sensitivity, insulin secretion, beta cell function and glucose effectiveness during development of non-diabetic hyperglycemia in a Japanese population
Published in SpringerPlus (20-05-2014)“…Since there had been no previous studies of alterations in insulin sensitivity, glucose-stimulated insulin secretion, beta cell function and glucose…”
Get full text
Journal Article -
10
2210-PUB: Nonselective Mineralocorticoid Receptor Antagonist May Alter Morning Elevation of Plasma Glucose Levels after Waking
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Previously, we reported that morning plasma glucose (PG) elevation before wake-up(W1) and after wake-up(W2), occur through different mechanisms in patients…”
Get full text
Journal Article -
11
Hyperbolic correlation between insulin sensitivity and insulin secretion fades away in lean subjects with superb glucose regulation
Published in Endocrine Journal (2012)“…The relationship between insulin sensitivity (Si) and insulin secretion (β) was analyzed in 533 health examinees. The subjects underwent a 75 g oral glucose…”
Get full text
Journal Article -
12
SGLT2 Inhibitors Suppress Alpha-Adrenergic Tone and Morning Elevation of Plasma Glucose Levels
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Previously, we reported that morning plasma glucose (PG) elevation before wake-up (W1) and after wake-up (W2), occur through different mechanisms in patients…”
Get full text
Journal Article -
13
Systematic Analysis of Risk Factors for Coronary Heart Disease in Japanese Patients with Type 2 Diabetes: A Matched Case-Control Study
Published in Journal of Atherosclerosis and Thrombosis (01-01-2012)“…Aim: To identify predictors of coronary heart disease (CHD) in Japanese patients with type 2 diabetes (T2DM). Methods: A matched case-control study was…”
Get full text
Journal Article -
14
Biphasic function of focal adhesion kinase in endothelial tube formation induced by fibril-forming collagens
Published in Biochemical and biophysical research communications (03-10-2008)“…Migration and tube formation of endothelial cells are important in angiogenesis and require a coordinated response to the extra-cellular matrix (ECM) and…”
Get full text
Journal Article -
15
Seizure and Profound Hypokalemia: Unusual Presentation of Primary Hyperparathyroidism
Published in European journal of case reports in internal medicine (30-06-2015)“…A 68-year-old man was admitted because of tonic–clonic convulsion. He had been receiving 200 mg itraconazole for 10 days. He had hypokalaemia (2.2 mEq/l),…”
Get full text
Journal Article -
16
Elevation of Serum Immunoglobulin G in Hashimoto's Thyroiditis and Decrease after Treatment with L-Thyroxine in Hypothyroid Patients
Published in Internal Medicine (01-01-2010)“…Objective We undertook an investigation on the frequency and magnitude of elevated serum immunoglobulin G (IgG), and effects of treatment with L-thyroxine (T4)…”
Get full text
Journal Article -
17
Mitogen-activated Protein Kinase Kinase Inhibition Does Not Block the Stimulation of Glucose Utilization by Insulin (∗)
Published in The Journal of biological chemistry (01-09-1995)“…Insulin stimulates the activity of mitogen-activated protein kinase (MAPK) via its upstream activator, MAPK kinase (MEK), a dual specificity kinase that…”
Get full text
Journal Article -
18
Selective Attenuation of Metabolic Branch of Insulin Receptor Down-signaling by High Glucose in a Hepatoma Cell Line, HepG2 Cells
Published in The Journal of biological chemistry (07-07-2000)“…The effects of a high concentration of glucose on the insulin receptor-down signaling were investigated in human hepatoma (HepG2) cells in vitro to delineate…”
Get full text
Journal Article -
19
Development, Worsening, and Improvement of Diabetic Microangiopathy in Older People: Six-Year Prospective Study of Patients Under Intensive Diabetes Control
Published in Journal of the American Geriatrics Society (JAGS) (01-04-2007)“…OBJECTIVES: To examine retinopathy and nephropathy in elderly patients with diabetes mellitus (DM) under intensive multifactorial DM control. DESIGN: Six‐year…”
Get full text
Journal Article -
20
Normal delivery following resection of an androgen-secreting adrenal carcinoma
Published in Reproductive medicine and biology (01-03-2011)“…A 31-year-old female presented to a gynecological clinic complaining of amenorrhea and virilism over a 2-month period. Blood tests revealed high serum total…”
Get full text
Journal Article