Search Results - "Yamashita, Yo‐ichi"
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Relationship between Fusobacterium nucleatum and antitumor immunity in colorectal cancer liver metastasis
Published in Cancer science (01-11-2021)“…Fusobacterium nucleatum has been detected in 8%‐13% of human colorectal cancer, and shown to inhibit immune responses against primary colorectal tumors in…”
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Impairment of perioperative activities of daily living is associated with poor prognosis following hepatectomy for hepatocellular carcinoma
Published in Journal of surgical oncology (01-11-2022)“…Background The number of cancer patients with impairment of activities of daily living (ADLs) has increased. This study aimed to examine associations of…”
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PD‐L1 expression enhancement by infiltrating macrophage‐derived tumor necrosis factor‐α leads to poor pancreatic cancer prognosis
Published in Cancer science (01-01-2019)“…Immunotherapy using anti‐PD‐1/PD‐L1 antibodies for several types of cancer has received considerable attention in recent decades. However, the molecular…”
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Lysyl oxidase induces epithelial‐mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma
Published in Cancer science (01-06-2019)“…Hepatocellular carcinoma (HCC) has high recurrence rates even after curative hepatectomy. Drug therapy for recurrence of HCC is still limited; therefore,…”
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Prognostic significance of a novel index score based on the inflammation-based prognostic scores of patients with colorectal cancer
Published in Journal of gastroenterology and hepatology (01-10-2023)“…This study aimed to clarify the prognostic value of various inflammation-based prognostic scores (IBPSs) in patients who underwent radical surgery for…”
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Survival impact of immune cells infiltrating peritumoral area of hepatocellular carcinoma
Published in Cancer science (01-12-2022)“…Inflammatory and immune cells in the tumor microenvironment are reported to be associated with tumor progression in several cancers. In total, 225 patients who…”
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Exploiting synergistic effect of externally loaded bFGF and endogenous growth factors for accelerated wound healing using heparin functionalized PCL/gelatin co-spun nanofibrous patches
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-01-2021)“…[Display omitted] •Heparin functionalized PCL/gelatin co-spun nanofibrous dressings were synthesized.•Fabricated dressings showed improved mechanical and…”
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Risk factors for bile leakage: Latest analysis of 10 102 hepatectomies for hepatocellular carcinoma from the Japanese national clinical database
Published in Journal of hepato-biliary-pancreatic sciences (01-07-2021)“…Background/Purpose The aim of this study was to identify risk factors for bile leakage in hepatic resections without biliary reconstructions using the large…”
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The Prognostic Impact of Controlling Nutritional Status (CONUT) in Intrahepatic Cholangiocarcinoma Following Curative Hepatectomy: A Retrospective Single Institution Study
Published in World journal of surgery (01-04-2018)“…Background Several studies have examined controlling nutritional status (CONUT), which is one of the useful biomarkers for predicting patients’ prognosis…”
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The microbiome and hepatobiliary-pancreatic cancers
Published in Cancer letters (28-08-2017)“…Abstract The human intestinal microbiome encompasses at least 100 trillion microorganisms that can influence host immunity and disease conditions, including…”
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Clinicopathological characteristics of combined hepatocellular cholangiocarcinoma from the viewpoint of patient prognosis after hepatic resection: High rate of early recurrence and its predictors
Published in Hepatology research (01-07-2020)“…Aim Combined hepatocellular cholangiocarcinoma (cHCC‐CCA) is a very rare subtype of primary liver carcinoma; therefore, its clinicopathological characteristics…”
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Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer
Published in Cancer science (01-02-2018)“…Chronic inflammation has a crucial role in cancer development and the progression of various tumors, including pancreatic ductal adenocarcinoma (PDAC). The…”
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Intraoperative bile culture helps choosing antibiotics in pancreaticoduodenectomy: Mechanistic profiling study of complex rink between bacterobilia and postoperative complications
Published in Journal of hepato-biliary-pancreatic sciences (01-12-2021)“…Background Postoperative complications after pancreaticoduodenectomy (PD) is still a major concern. The aim of this study was to propose how to choose…”
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Clinical Significance of PD-L1 Expression in Both Cancer and Stroma Cells of Cholangiocarcinoma Patients
Published in Annals of surgical oncology (01-02-2020)“…Background The clinical significance of programmed death 1 and its ligand (PD-L1) as therapeutic targets has been reported previously. This study aimed to…”
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CXCL12 expression in intrahepatic cholangiocarcinoma is associated with metastasis and poor prognosis
Published in Cancer science (01-10-2019)“…Intrahepatic cholangiocarcinoma is a rare malignant biliary neoplasm that causes a poor prognosis even after curative hepatectomy. Liver metastasis is the…”
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Sarcopenia Affects Systemic and Local Immune System and Impacts Postoperative Outcome in Patients with Extrahepatic Cholangiocarcinoma
Published in World journal of surgery (15-09-2019)“…Background A decrease in skeletal muscle mass and function, defined as sarcopenia, is associated with poor postoperative outcome in patients with cancers…”
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The Impact of Histologic Liver Inflammation on Oncology and the Prognosis of Patients Undergoing Hepatectomy for Hepatocellular Carcinoma
Published in Annals of surgical oncology (01-02-2022)“…Background Liver inflammation is a reaction to disease-causing stress in the liver that induces fibrosis and cirrhosis. However, its prognostic impact after…”
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Cancer-associated fibroblast senescence and its relation with tumour-infiltrating lymphocytes and PD-L1 expressions in intrahepatic cholangiocarcinoma
Published in British journal of cancer (01-02-2022)“…Background Caveolin-1 (CAV1) in cancer-associated fibroblasts (CAFs) has pro- or anti-tumourigenic effect depending on the cancer type. However, its effect in…”
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Nrf2 promotes oesophageal cancer cell proliferation via metabolic reprogramming and detoxification of reactive oxygen species
Published in The Journal of pathology (01-03-2018)“…Cancer cells consume a large amount of energy and maintain high levels of anabolism to promote cell proliferation via metabolic reprogramming. Nuclear factor…”
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Recent advances in precision medicine for pancreatic ductal adenocarcinoma
Published in Annals of gastroenterological surgery (01-07-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer mortality worldwide. Although advances in systemic chemotherapy for PDAC have…”
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