Search Results - "Yamasaki, Takahisa"
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Recent understanding of the pathophysiology of functional dyspepsia: role of the duodenum as the pathogenic center
Published in Journal of gastroenterology (01-04-2019)“…Over almost 30 years since functional dyspepsia (FD) was defined, researchers have endeavored to elucidate the pathophysiology of functional gastrointestinal…”
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The Changing Epidemiology of Gastroesophageal Reflux Disease: Are Patients Getting Younger?
Published in Journal of neurogastroenterology and motility (01-10-2018)“…Gastroesophageal reflux disease (GERD) is a common disease globally with increasing prevalence and consequently greater burden on the Healthcare system…”
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A novel prostanoid EP1 receptor antagonist, ONO-8539, reduces acid-induced heartburn symptoms in healthy male volunteers: a randomized clinical trial
Published in Journal of gastroenterology (01-10-2017)“…Background Patients with proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease (GERD) have unmet clinical needs. Recently, we reported that…”
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4
Long-term effects of H. pylori eradication on epigenetic alterations related to gastric carcinogenesis
Published in Scientific reports (25-09-2018)“…The risk of gastric cancer (GC) remains in precancerous conditions, including atrophic mucosa and intestinal mucosa (IM), even after H . pylori treatment. To…”
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A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia
Published in Journal of gastroenterology (01-05-2017)“…Background Acotiamide is widely used to improve symptoms in patients with functional dyspepsia (FD) in multiple large-scale clinical studies, but there are few…”
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Reflux Hypersensitivity: A New Functional Esophageal Disorder
Published in Journal of neurogastroenterology and motility (30-10-2017)Get full text
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Correction to: Effect of Vonoprazan, a Potassium-Competitive Acid Blocker, on the 13C-Urea Breath Test in Helicobacter pylori-Positive Patients
Published in Digestive diseases and sciences (01-07-2021)“…A correction to this paper has been published: https://doi.org/10.1007/s10620-021-07090-3…”
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Prevalence and Self-recognition of Chronic Constipation: Results of an Internet Survey
Published in Journal of neurogastroenterology and motility (30-10-2016)“…Although chronic constipation is a common symptom, to date no international consensus has been reached regarding its definition. The aims of this study were…”
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Correction to: A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia
Published in Journal of gastroenterology (01-02-2021)“…The original article can be found online…”
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10
Claudin-2 expression is upregulated in the ileum of diarrhea predominant irritable bowel syndrome patients
Published in Journal of Clinical Biochemistry and Nutrition (2017)“…Intestinal epithelial barrier function is impaired in irritable bowel syndrome patients. Claudins are highly expressed in cells with tight junctions and are…”
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A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation
Published in Journal of neurogastroenterology and motility (01-10-2019)“…Magnesium oxide (MgO) has been frequently used as a treatment for chronic constipation (CC) since the 1980s in Japan. The aim of this study is to evaluate its…”
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Chenodeoxycholic Acid Releases Proinflammatory Cytokines from Small Intestinal Epithelial Cells Through the Farnesoid X Receptor
Published in Digestion (2019)“…Bile acids have recently been associated with the pathogenesis of irritable bowel syndrome (IBS). We therefore evaluated the expression of bile acid receptors…”
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13
Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia
Published in Journal of neurogastroenterology and motility (30-07-2017)“…Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia…”
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14
Morphological Characteristics of Early Gastric Neoplasms Detected After Helicobacter pylori Eradication
Published in Digestive diseases and sciences (01-06-2016)“…Background Previous morphological studies indicated that the eradication of Helicobacter pylori ( H. pylori ) made gastric neoplasms endoscopically indistinct…”
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The incidence of “silent” free air and aspiration pneumonia detected by CT after gastric endoscopic submucosal dissection
Published in Gastrointestinal endoscopy (01-12-2012)“…Background Although endoscopic submucosal dissection (ESD) is feasible as a treatment for early gastric cancer, it requires great skill to perform and may…”
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Barrett’s esophagus patients are becoming younger: analysis of a large United States dataset
Published in Esophagus : official journal of the Japan Esophageal Society (01-04-2020)“…Background Barrett’s esophagus (BE), a complication of long-term gastroesophageal reflux disease (GERD), has been reported to affect 6–8% of those with…”
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Sex differences in associations among metabolic syndrome, obesity, related biomarkers, and colorectal adenomatous polyp risk in a Japanese population
Published in Journal of Clinical Biochemistry and Nutrition (01-01-2018)“…To investigate sex differences in the associations among metabolic syndrome, obesity, adipose tissue-related biomarkers, and colorectal adenomatous polyps, a…”
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Esophageal Epithelial-Derived IL-33 Is Upregulated in Patients with Heartburn
Published in PloS one (25-04-2016)“…Interleukin-33 (IL-33) is a tissue-derived cytokine that is constitutively expressed in epithelial cells of tissues exposed to the environment and plays a role…”
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Effect of Vonoprazan, a Potassium-Competitive Acid Blocker, on the 13C-Urea Breath Test in Helicobacter pylori-Positive Patients
Published in Digestive diseases and sciences (01-03-2017)“…Background and Aim Vonoprazan (VPZ) is a new oral potassium-competitive acid blocker that has recently become available. The aim of this study was to…”
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Effect of age and correlation between esophageal visceral chemosensitivity and mechanosensitivity in healthy Japanese subjects
Published in Journal of gastroenterology (01-03-2013)“…Background The aim of this study was to examine the impact of age on esophageal sensation, and to determine whether esophageal mechanosensitivity and…”
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