Search Results - "Yamamura, Takaki"
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Thermodynamic stability of human lipocalin-type prostaglandin D synthase under various pH conditions
Published in Journal of biochemistry (Tokyo) (30-06-2023)“…Lipocalin-type prostaglandin D synthase (L-PGDS) binds various hydrophobic small molecules. Since we aim to use human L-PGDS as a carrier in a drug delivery…”
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Zinc mediates the interaction between ceruloplasmin and apo-transferrin for the efficient transfer of Fe(III) ions
Published in Metallomics (21-12-2021)“…Fe(II) exported from cells is oxidized to Fe(III), possibly by a multicopper ferroxidase (MCF) such as ceruloplasmin (CP), to efficiently bind with the plasma…”
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Phytoestrogens Inhibiting Androgen Receptor Signal and Prostate Cancer Cell Proliferation
Published in Chemical research in Chinese universities (01-10-2013)“…The androgen receptor(AR) signaling activated by dihydrotestosterone(DHT) plays critical roles in pros- tate cancer development and progression…”
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Xeno-oestrogens Bisphenol A and Diethylstilbestrol Selectively Activating Androgen Receptor Mediated AREs-TATA Reporter System
Published in Chemical research in Chinese universities (01-06-2013)“…We cloned the three androgen response elements(AREs, including AREI, AREII, and AREIII ) with a core transactivation TATA element of the prostate-specific…”
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Cathepsin K Antisense Oligodeoxynucleotide Inhibits Osteoclastic Bone Resorption
Published in The Journal of biological chemistry (28-03-1997)“…Cathepsin K is a recently identified cysteine protease which is abundantly and selectively expressed in osteoclasts. To evaluate the contribution of cathepsin…”
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A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor
Published in Biochemical and biophysical research communications (30-04-1992)“…A series of C-terminal linear peptides of endothelin (ET)-1 and their N alpha-succinyl (Suc) analogs were synthesized and their binding affinities for the two…”
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Pharmacological characterization of endothelin‐induced rat pulmonary arterial dilatation
Published in British journal of pharmacology (01-06-1997)“…The aim of study was to characterize endothelin (ET)‐induced vasodilatation in isolated extrapulmonary rat arteries (EPA) and in intrapulmonary arteries (IPA)…”
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Nerve growth factor induces resistance of PC12 cells to nitric oxide cytotoxicity
Published in Neurochemistry international (01-11-1996)“…Nitric oxide (NO) donors, sodium nitroprusside and NOC 7, caused pheochromocytoma (PC12) cell death in a concentration and time-dependent manner. This…”
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Selective activation of excitation‐contraction coupling pathways by ETA and ETB receptors in guinea‐pig tracheal smooth muscle
Published in British journal of pharmacology (01-02-1999)“…Signalling events responsible for endothelinA (ETA) and ETB receptor‐induced contraction were examined in epithelium‐denuded guinea‐pig tracheal smooth muscle…”
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Techniques for measurement of nitric oxide in biological systems: principles and practice
Published in Nihon yakurigaku zasshi (1996)“…Despite being small and simple in structure the nitric oxide free radical (NO.) is now proving to be of vital physiological significance, and it has been shown…”
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Absence of Binding Between the Human Transferrin Receptor and the Transferrin Complex of Biological Toxic Trace Element, Aluminum, Because of an Incomplete Open/Closed Form of the Complex
Published in Biological trace element research (01-09-2010)“…Human transferrin (Tf) very tightly binds two ferric ions to deliver iron to cells. Fe(III)₂Tf (Fe₂Tf) binds to the Tf receptor (TfR) at pH 7.4; however,…”
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Computational Structure Models of Apo and Diferric Transferrin–Transferrin Receptor Complexes
Published in The Protein Journal (01-12-2009)“…Complexation of transferrin (Tf) and its receptor (TfR) is an essential event for iron uptake by the cell. Much data has been accumulated regarding Tf-TfR…”
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Capillary Electrophoresis and Computational analysis of human serum transferrin and its receptor complex for the surface changes in physicochemical properties
Published in The FASEB journal (01-03-2008)“…Abstract only Transferrins (Tfs) are a family of homologous iron‐binding proteins, e.g., serum transferrin (STf), lactoferrin (LTf), ovotransferrin (OTf), that…”
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Molecular dynamics approach to study the discrepancies in the thermal behavior of amylose and chitosan conformations
Published in Journal of molecular structure. Theochem (30-05-2006)“…A unique discrepancy in the thermal behavior exists between two species of linear polysaccharides of amylose with of α(1→4) linked d-glucan and of chitosan…”
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In situ emission levels of carcinogenic and mutagenic compounds from diesel and gasoline engine vehicles on an expressway
Published in Environmental science & technology (01-12-1984)“…The in situ emission levels of polycyclic aromatic hydrocarbons (PAHs), their nitro derivatives (NPAHs), polycyclic quinones (PQu's), aza heterocyclic…”
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Antiproliferative and apoptotic effects of pinocembrin in human prostate cancer cells
Published in Bangladesh journal of pharmacology (01-01-2013)Get full text
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Selective activation of excitation‐contraction coupling pathways by ET A and ET B receptors in guinea‐pig tracheal smooth muscle
Published in British journal of pharmacology (29-01-2009)“…Signalling events responsible for endothelin A (ET A ) and ET B receptor‐induced contraction were examined in epithelium‐denuded guinea‐pig tracheal smooth…”
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Different stability of N- and C-domain of diferric ovotransferrin in urea and application to the determination of iron distribution between the two domains
Published in Journal of biochemistry (Tokyo) (1988)“…The study of guanidine-HCl or thermal denaturation of diferric ovotransferrin (Fe2Tf) has revealed a simultaneous unfolding of the two domains of the protein…”
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Ca2+ -independent contraction induced by endothelin-1 in rat aortal smooth muscle
Published in Japanese Journal of Pharmacology (2000)“…The necessity of Ca^2+ for endothelin_A (ET_A ) receptor-mediated contraction was examined in rat endothelium-denuded aortal smooth muscle rings. In the…”
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