Search Results - "Yamamoto, Tatsuro"

Nuclear microenvironment in cancer: Control through liquid‐liquid phase separation by Nozawa, Ryu‐Suke, Yamamoto, Tatsuro, Takahashi, Motoko, Tachiwana, Hiroaki, Maruyama, Reo, Hirota, Toru, Saitoh, Noriko

“…The eukaryotic nucleus is not a homogenous single‐spaced but a highly compartmentalized organelle, partitioned by various types of membraneless structures,…”
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Gene regulation by non-coding RNAs in the 3D genome architecture by Tachiwana, Hiroaki, Yamamoto, Tatsuro, Saitoh, Noriko

“…Appropriate gene expression is essential for producing the correct amount of proteins at the right time, which is critical for living organisms. In the…”
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BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene by Yamamoto, Tatsuro, Hirosue, Akiyuki, Nakamoto, Masafumi, Yoshida, Ryoji, Sakata, Junki, Matsuoka, Yuichiro, Kawahara, Kenta, Nagao, Yuka, Nagata, Masashi, Takahashi, Nozomu, Hiraki, Akimitsu, Shinohara, Masanori, Nakao, Mitsuyoshi, Saitoh, Noriko, Nakayama, Hideki

“…Background Oral squamous cell carcinoma (OSCC) has increased morbidity, and its high metastatic potential affects patient survival. Bromodomain containing 4…”
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The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies by Suzuki, Hidefumi, Abe, Ryota, Shimada, Miho, Hirose, Tomonori, Hirose, Hiroko, Noguchi, Keisuke, Ike, Yoko, Yasui, Nanami, Furugori, Kazuki, Yamaguchi, Yuki, Toyoda, Atsushi, Suzuki, Yutaka, Yamamoto, Tatsuro, Saitoh, Noriko, Sato, Shigeo, Tomomori-Sato, Chieri, Conaway, Ronald C., Conaway, Joan W., Takahashi, Hidehisa

“…Non-polyadenylated mRNAs of replication-dependent histones (RDHs) are synthesized by RNA polymerase II (Pol II) at histone locus bodies (HLBs). HLBs frequently…”
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The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis by Abdalla, Mohamed Osama Ali, Yamamoto, Tatsuro, Maehara, Kazumitsu, Nogami, Jumpei, Ohkawa, Yasuyuki, Miura, Hisashi, Poonperm, Rawin, Hiratani, Ichiro, Nakayama, Hideki, Nakao, Mitsuyoshi, Saitoh, Noriko

“…MCF7 cells acquire estrogen-independent proliferation after long-term estrogen deprivation (LTED), which recapitulates endocrine therapy resistance. LTED cells…”
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Development of a New Method for Simultaneous Quantitation of Plasma Concentrations of Voriconazole and Voriconazole N-Oxide Using Column-Switching LC-MS/MS and Its Application in Therapeutic Drug Monitoring by Yamamoto, Tatsuro, Ishida, Masako, Kodama, Nao, Saiki, Yusuke, Fujiyoshi, Masachika, Shimada, Miki

“…[ABSTRACT] [Background] Voriconazole therapy for fungal infections usually continues for several years and is often administered on an outpatient basis…”
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Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection by Sakurai, Fuminori, Mitani, Seiji, Yamamoto, Tatsuro, Takayama, Kazuo, Tachibana, Masashi, Watashi, Koichi, Wakita, Takaji, Iijima, Sayuki, Tanaka, Yasuhito, Mizuguchi, Hiroyuki

“…In order to understand the life cycle of hepatitis B virus (HBV) and to develop efficient anti-HBV drugs, a useful in vitro cell culture system which allows…”
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Circulating miRNA-1290 as a potential biomarker for response to chemoradiotherapy and prognosis of patients with advanced oral squamous cell carcinoma: A single-center retrospective study by Nakashima, Hikaru, Yoshida, Ryoji, Hirosue, Akiyuki, Kawahara, Kenta, Sakata, Junki, Arita, Hidetaka, Yamamoto, Tatsuro, Toya, Ryo, Murakami, Ryuji, Hiraki, Akimitsu, Shinohara, Masanori, Ito, Takaaki, Kuwahara, Yoshikazu, Nakayama, Hideki

“…MicroRNAs are a class of small, endogenous, noncoding 18- to 24-nucleotide-long RNAs that can regulate multiple processes related to cancer progression…”
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Endocrine therapy-resistant breast cancer model cells are inhibited by soybean glyceollin I through Eleanor non-coding RNA by Yamamoto, Tatsuro, Sakamoto, Chiyomi, Tachiwana, Hiroaki, Kumabe, Mitsuru, Matsui, Toshiro, Yamashita, Tadatoshi, Shinagawa, Masatoshi, Ochiai, Koji, Saitoh, Noriko, Nakao, Mitsuyoshi

“…Long-term estrogen deprivation (LTED) of an estrogen receptor (ER) α-positive breast cancer cell line recapitulates cancer cells that have acquired…”
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HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma by Sakata, Junki, Hirosue, Akiyuki, Yoshida, Ryoji, Kawahara, Kenta, Matsuoka, Yuichiro, Yamamoto, Tatsuro, Nakamoto, Masafumi, Hirayama, Masatoshi, Takahashi, Nozomu, Nakamura, Takuya, Arita, Hidetaka, Nakashima, Hikaru, Nagata, Masashi, Hiraki, Akimitsu, Shinohara, Masanori, Nakayama, Hideki

“…The highly malignant phenotype of oral squamous cell carcinoma (OSCC), including the presence of nodal and distant metastasis, reduces patient survival…”
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Isomaltodextrin, a highly branched α-glucan, increases rat colonic H2 production as well as indigestible dextrin by Nishimura, Naomichi, Tanabe, Hiroki, Yamamoto, Tatsuro

“…Colonic hydrogen (H 2 ) protects against inflammation-induced oxidative stress. We examined the effect of a new highly branched α-glucan, isomaltodextrin…”
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Mechanism Underlying Conflicting Drug-Drug Interaction Between Aprepitant and Voriconazole via Cytochrome P450 3A4-Mediated Metabolism by Ishida, Masako, Kumagai, Takeshi, Yamamoto, Tatsuro, Suzuki, Hiroyuki, Moriki, Kuniaki, Fujiyoshi, Masachika, Nagata, Kiyoshi, Shimada, Miki

“…[ABSTRACT] [Background] Voriconazole is an antifungal drug for which therapeutic monitoring is recommended to prevent side effects. Temporary administration of…”
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Colonic hydrogen generated from fructan diffuses into the abdominal cavity and reduces adipose mRNA abundance of cytokines in rats by Nishimura, Naomichi, Tanabe, Hiroki, Adachi, Misato, Yamamoto, Tatsuro, Fukushima, Michihiro

“…Hydrogen (H2) protects against inflammation-induced oxidative stress. Nondigestible saccharides (NDSs) enhance colonic H2 production. We examined whether…”
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Sufficient intake of high amylose cornstarch maintains high colonic hydrogen production for 24 h in rats by Nishimura, Naomichi, Tanabe, Hiroki, Yamamoto, Tatsuro

“…Colonic hydrogen (H 2 ) can suppress oxidative stress and damage in the body. We examined the minimum requirement of high amylose cornstarch (HAS) to maintain…”
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Transplantation of High Hydrogen-Producing Microbiota Leads to Generation of Large Amounts of Colonic Hydrogen in Recipient Rats Fed High Amylose Maize Starch by Nishimura, Naomichi, Tanabe, Hiroki, Komori, Erika, Sasaki, Yumi, Inoue, Ryo, Yamamoto, Tatsuro

“…The hydrogen molecule (H₂), which has low redox potential, is produced by colonic fermentation. We examined whether increased hydrogen (H₂) concentration in…”
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Treatment of chronic pain by Yamamoto, Tatsuro

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Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia–reperfusion injury in rats by Nishimura, Naomichi, Tanabe, Hiroki, Sasaki, Yumi, Makita, Yui, Ohata, Misako, Yokoyama, Saori, Asano, Mami, Yamamoto, Tatsuro, Kiriyama, Shuhachi

“…We investigated whether the feeding of high H2-generating dietary fibre and resistant starch (RS) could suppress hepatic ischaemia–reperfusion (IR) injury,…”
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Nucleosome destabilization by nuclear non-coding RNAs by Fujita, Risa, Yamamoto, Tatsuro, Arimura, Yasuhiro, Fujiwara, Saori, Tachiwana, Hiroaki, Ichikawa, Yuichi, Sakata, Yuka, Yang, Liying, Maruyama, Reo, Hamada, Michiaki, Nakao, Mitsuyoshi, Saitoh, Noriko, Kurumizaka, Hitoshi

“…In the nucleus, genomic DNA is wrapped around histone octamers to form nucleosomes. In principle, nucleosomes are substantial barriers to transcriptional…”
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Dual labeling with 5‐bromo‐2'‐deoxyuridine and 5‐ethynyl‐2'‐deoxyuridine for estimation of cell migration rate in the small intestinal epithelium by Asano, Mami, Yamamoto, Tatsuro, Tsuruta, Takeshi, Nishimura, Naomichi, Sonoyama, Kei

“…Small intestinal epithelium is a self‐renewing system in which the entire sequence of cell proliferation, differentiation, and removal is coupled to cell…”
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Roles of long noncoding RNAs in chromosome domains by Tomita, Saori, Abdalla, Mohamed Osama Ali, Fujiwara, Saori, Yamamoto, Tatsuro, Iwase, Hirotaka, Nakao, Mitsuyoshi, Saitoh, Noriko

“…The cell nucleus is highly organized and functionally compartmentalized. Double‐stranded naked DNA is complexed with core histones and assembled into…”
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