Search Results - "Yamamoto, Shohei"

Self-organization of Plk4 regulates symmetry breaking in centriole duplication by Yamamoto, Shohei, Kitagawa, Daiju

“…During centriole duplication, a single daughter centriole is formed next to the mother centriole. The molecular mechanism that determines a single duplication…”
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A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination by Zhang, Jingjing, Fujiwara, Yasuhiro, Yamamoto, Shohei, Shibuya, Hiroki

“…Homologous recombination (HR) repairs DNA double-strand breaks (DSBs) to maintain genomic integrity. Recombinase recruited to the DSBs by the mediator protein…”
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The Synthetic Curcumin Derivative CNB-001 Attenuates Thrombin-Stimulated Microglial Inflammation by Inhibiting the ERK and p38 MAPK Pathways by Akaishi, Tatsuhiro, Yamamoto, Shohei, Abe, Kazuho

“…We have recently found that the synthetic curcumin derivative CNB-001 suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) production in cultured…”
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3′,4′-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT–mTOR and NF-κB Pathways by Akaishi, Tatsuhiro, Yamamoto, Shohei, Abe, Kazuho

“…Microglia-related neuroinflammation contributes to the pathogenesis of a variety of neurodegenerative disorders such as Alzheimer’s disease. The synthetic…”
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3′,4′,7-Trihydroxyflavone Downregulates NO Production in LPS- or IFN-γ-Activated MG6 Microglial Cells by Attenuating the JNK–STAT1 Pathway by Akaishi, Tatsuhiro, Yamamoto, Shohei, Abe, Kazuho

“…Neuroinflammation induced by activated microglia is a key feature of neurodegenerative diseases such as Alzheimer’s disease. The natural flavonoid…”
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A theory of centriole duplication based on self-organized spatial pattern formation by Takao, Daisuke, Yamamoto, Shohei, Kitagawa, Daiju

“…In each cell cycle, centrioles are duplicated to produce a single copy of each preexisting centriole. At the onset of centriole duplication, the master…”
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Association of Changes of lifestyle behaviors before and during the COVID-19 pandemic with mental health: a longitudinal study in children and adolescents by Xiang, Mi, Liu, Yujie, Yamamoto, Shohei, Mizoue, Tetsuya, Kuwahara, Keisuke

“…Abstract Background We examined the prospective associations of changes in lifestyle behaviors before/during the COVID-19 pandemic, namely physical activity…”
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Coffee and Green Tea Consumption With the Risk of COVID-19 Among the Vaccine Recipients in Japan: A Prospective Study by Islam, Zobida, Yamamoto, Shohei, Mizoue, Tetsuya, Konishi, Maki, Ohmagari, Norio

“…Background: While coffee and green tea have been suggested to have immunoprotective effects, it remains elusive whether they can decrease the risk of…”
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Trajectory of Lean Body Mass Assessed Using the Modified Creatinine Index and Mortality in Hemodialysis Patients by Suzuki, Yuta, Matsuzawa, Ryota, Kamiya, Kentaro, Hoshi, Keika, Harada, Manae, Watanabe, Takaaki, Shimoda, Takahiro, Yamamoto, Shohei, Matsunaga, Yusuke, Yoshida, Atsushi, Matsunaga, Atsuhiko

“…Although a declining body mass index (BMI) is associated with higher mortality in patients on hemodialysis, BMI cannot distinguish lean body mass from fat…”
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The Antecedents and Consequences of Workaholism: Findings From the Modern Japanese Labor Market by Akutsu, Satoshi, Katsumura, Fumiaki, Yamamoto, Shohei

“…The present study examined the direct and indirect ( workaholism) relationships between competitive work environments and subjective unhealthiness. It also…”
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Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies by Yang, Hui, Kurtenbach, Stefan, Guo, Ying, Lohse, Ines, Durante, Michael A., Li, Jianping, Li, Zhaomin, Al-Ali, Hassan, Li, Lingxiao, Chen, Zizhen, Field, Matthew G., Zhang, Peng, Chen, Shi, Yamamoto, Shohei, Li, Zhuo, Zhou, Yuan, Nimer, Stephen D., Harbour, J. William, Wahlestedt, Claes, Xu, Mingjiang, Yang, Feng-Chun

“…Additional Sex Combs-Like 1 (ASXL1) is mutated at a high frequency in all forms of myeloid malignancies associated with poor prognosis. We generated a Vav1…”
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Comparison of the association between six different frailty scales and clinical events in patients on hemodialysis by Imamura, Keigo, Yamamoto, Shohei, Suzuki, Yuta, Yoshikoshi, Shun, Harada, Manae, Osada, Shiwori, Kamiya, Kentaro, Matsuzawa, Ryota, Matsunaga, Atsuhiko

“…Frailty is associated with adverse outcomes in patients undergoing hemodialysis (HD). However, no study has used various frailty assessments in patients on HD…”
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Blow-off process of highly under-expanded hydrogen non-premixed jet flame by Yamamoto, Shohei, Sakatsume, Ryo, Takeno, Keiji

“…Relationships between flame lift-off heights and reservoir pressure were experimentally investigated in order to clarify blow-off process of hydrogen…”
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Cobalt-Catalyzed C-4 Selective Alkylation of Quinolines by Yamamoto, Shohei, Saga, Yutaka, Andou, Takashi, Matsunaga, Shigeki, Kanai, Motomu

“…The cobalt‐catalyzed direct C‐4 selective alkylation of quinolines is described. The reaction conditions used previously for pyridines were fully modified to…”
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Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population by Yamamoto, Shohei, Inoue, Yosuke, Kuwahara, Keisuke, Miki, Takako, Nakagawa, Tohru, Honda, Toru, Yamamoto, Shuichiro, Hayashi, Takeshi, Mizoue, Tetsuya

“…Physical activity has been linked to a lower risk of chronic kidney disease (CKD); however, evidence on the relationship between domain-specific physical…”
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Proposal of novel natural inhibitors of severe acute respiratory syndrome coronavirus 2 main protease: Molecular docking and ab initio fragment molecular orbital calculations by Shaji, Divya, Yamamoto, Shohei, Saito, Ryosuke, Suzuki, Ryo, Nakamura, Shunya, Kurita, Noriyuki

“…This paper proposes natural drug candidate compounds for the treatment of coronavirus disease 2019 (COVID-19). We investigated the binding properties between…”
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Actin network architecture can ensure robust centering or sensitive decentering of the centrosome by Yamamoto, Shohei, Gaillard, Jérémie, Vianay, Benoit, Guerin, Christophe, Orhant‐Prioux, Magali, Blanchoin, Laurent, Théry, Manuel

“…The orientation of cell polarity depends on the position of the centrosome, the main microtubule‐organizing center (MTOC). Microtubules (MTs) transmit pushing…”
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The clinical applicability of ultrasound technique for diagnosis of sarcopenia in hemodialysis patients by Matsuzawa, Ryota, Yamamoto, Shohei, Suzuki, Yuta, Imamura, Keigo, Harada, Manae, Matsunaga, Atsuhiko, Tamaki, Akira, Fukui, Takayuki, Shimokado, Kiyoshi

“…We examined the validity of ultrasound technique assessing muscle mass and reflecting muscle strength and physical performance, and the clinical applicability…”
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Association between reactogenicity and SARS-CoV-2 antibodies after the second dose of the BNT162b2 COVID-19 vaccine by Yamamoto, Shohei, Fukunaga, Ami, Tanaka, Akihito, Takeuchi, Junko S., Inoue, Yosuke, Kimura, Moto, Maeda, Kenji, Ueda, Gohzoh, Mizoue, Tetsuya, Ujiie, Mugen, Sugiura, Wataru, Ohmagari, Norio

“…High vaccine reactogenicities may reflect stronger immune responses, but the epidemiological evidence for coronavirus disease 2019 (COVID-19) vaccines is…”
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Novel TENM3–ALK fusion is an alternate mechanism for ALK activation in neuroblastoma by Hiwatari, Mitsuteru, Seki, Masafumi, Matsuno, Ryosuke, Yoshida, Kenichi, Nagasawa, Takeshi, Sato-Otsubo, Aiko, Yamamoto, Shohei, Kato, Motohiro, Watanabe, Kentaro, Sekiguchi, Masahiro, Miyano, Satoru, Ogawa, Seishi, Takita, Junko

“…The identification of molecular events underlying the pathogenesis of neuroblastoma can likely result in improved clinical outcomes for this disease. In this…”
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