Search Results - "Yamamoto, Lynn"
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Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis
Published in PloS one (03-06-2020)“…Extracellular adenosine triphosphate (eATP) released by damaged cells, and its purinergic receptors, comprise a crucial signaling network after injury…”
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Common Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Epitopes Mediate Multiple Routes for Internalization and Function
Published in PloS one (23-04-2015)“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a soluble protein that directs membrane-bound receptors to lysosomes for degradation. In the most…”
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Strain level and comprehensive microbiome analysis in inflammatory bowel disease via multi-technology meta-analysis identifies key bacterial influencers of disease
Published in Frontiers in microbiology (14-10-2022)“…Objective Inflammatory bowel disease (IBD) is a heterogenous disease in which the microbiome has been shown to play an important role. However, the precise…”
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SAT-387-Pharmacological inhibition of P2X7 receptor ameliorates liver injury in nonhuman primates by reducing liver inflammation and fibrosis
Published in Journal of hepatology (01-04-2019)Get full text
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SELECTION OF MICROBIOME-DERIVED PEPTIDES THROUGH MULTI-TECHNOLOGY META-ANALYSIS, BINDING, AND FUNCTIONAL ASSAYS, IDENTIFIES PEPTIDES WITH THERAPEUTIC POTENTIAL THAT MODULATE IMMUNE RESPONSES AND DISEASE
Published in Inflammatory bowel diseases (22-01-2022)“…Abstract Microbiome-driven drug discovery holds great promise for therapeutic development. However, identification of disease-associated microbiome-host…”
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Mutator Effects in Escherichia coli Caused by the Expression of Specific Foreign Genes
Published in Journal of Bacteriology (01-07-2005)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A NOVEL MICROBIALLY-DERIVED PROTEIN CAN BE EXPRESSED IN LACTOCOCCUS LACTIS AND DELIVERED ORALLY TO IMPROVE GUT BARRIER FUNCTION AND PREVENT FIBROGENESIS BY INTERACTING WITH THE EXTRACELLULAR MATRIX DURING GI INJURY
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2022)Get full text
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A NOVEL MICROBIALLY-DERIVED PROTEIN CAN BE EXPRESSED IN LACTOCOCCUS LACTIS AND DELIVERED ORALLY TO IMPROVE GUT BARRIER FUNCTION AND PREVENT FIBROGENESIS BY INTERACTING WITH THE EXTRACELLULAR MATRIX DURING GI INJURY
Published in Inflammatory bowel diseases (22-01-2022)“…Abstract Intestinal barrier dysfunction or the loss of the epithelial integrity allowing the permeation of microorganisms, dietary antigens and other particles…”
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Abstract PR08: Novel microbiome-derived peptides modulate immune cell activity and the tumor microenvironment
Published in Cancer research (Chicago, Ill.) (15-04-2020)“…Abstract The gut microbiota has emerged as an important player in cancer pathology, and increasing evidence supports its role in clinical response to immune…”
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Common Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Epitopes Mediate Multiple Routes for Internalization and Function: e0125127
Published in PloS one (01-04-2015)“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a soluble protein that directs membrane-bound receptors to lysosomes for degradation. In the most…”
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Decreased oxidative DNA damage in Ogg1/Myh‐deficient mice treated with pomegranate extract
Published in The FASEB journal (01-04-2007)“…Oxidative DNA damage is linked to carcinogenesis. Base excision repair (BER) is critical for the repair of oxidative DNA lesions such as…”
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Gene -environment interactions: Roles of DNA repair proteins in preventing disease and injury
Published 01-01-2009“…Understanding gene-environment interactions are important because people are continuously exposed to variables which may impact their health. In a…”
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Dissertation -
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Functional characterization of N-gene mediated signaling leading to TMV resistance in solanaceous species
Published 01-01-2005“…Plants possess natural preformed mechanisms for defense against pathogens. Gene-for-gene resistance is an effective resistance strategy in which a single…”
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Functional characterization of N-gene mediated signaling leading to TMV resistance in solanaceous species
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Gene-environment interactions: Roles of DNA repair proteins in preventing disease and injury
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Dissertation -
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Will inverting orthographic neighbors enhance neighborhood frequency effects?
Published 01-01-2002“…Some experiments report that neighborhood frequency effects yield faster lexical access times, while others report neighborhood size. In the current study,…”
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Dissertation -
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A standardized procedure for quantification of the Ames Salmonella/mammalian-microsome mutagenicity test
Published in Environmental mutagenesis (1981)“…Factors determining the precision and variability of the Ames Salmonella test for mutagenicity were investigated. The most important source of variability in…”
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