Search Results - "Yamamoto, Kuniharu"

BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma by Tamai, Keiichi, Nakamura-Shima, Mao, Shibuya-Takahashi, Rie, Kanno, Shin-Ichiro, Yasui, Akira, Mochizuki, Mai, Iwai, Wataru, Wakui, Yuta, Abue, Makoto, Yamamoto, Kuniharu, Miura, Koh, Mizuma, Masamichi, Unno, Michiaki, Kawamura, Sadafumi, Sato, Ikuro, Yasuda, Jun, Yamaguchi, Kazunori, Sugamura, Kazuo, Satoh, Kennichi

“…Cancer stem cells (CSCs) define a subpopulation of cancer cells that are resistant to therapy. However, little is known of how CSC characteristics are…”
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Comparison of CEA and CA19-9 as a predictive factor for recurrence after curative gastrectomy in gastric cancer by Shibata, Chikashi, Nakano, Toru, Yasumoto, Akihiro, Mitamura, Atsushi, Sawada, Kentaro, Ogawa, Hitoshi, Miura, Tomoya, Ise, Ichiro, Takami, Kazuhiro, Yamamoto, Kuniharu, Katayose, Yu

“…Our aim of was to compare importance of the tumor markers (TMs) serum carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 in prediction of…”
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Major hepatectomy for perihilar cholangiocarcinoma by Unno, Michiaki, Katayose, Yu, Rikiyama, Toshiki, Yoshida, Hiroshi, Yamamoto, Kuniharu, Morikawa, Takanori, Hayashi, Hiroki, Motoi, Fuyuhiko, Egawa, Shinichi

“…Background/purpose Hilar cholangiocarcinoma and intrahepatic cholangiocarcinoma involving the hepatic hilus are defined as “perihilar cholangiocarcinoma”. The…”
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Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species by Yokoyama, Misa, Tanuma, Nobuhiro, Shibuya, Rie, Shiroki, Takeharu, Abue, Makoto, Yamamoto, Kuniharu, Miura, Koh, Yamaguchi, Kazunori, Sato, Ikuro, Tamai, Keiichi, Satoh, Kennichi

“…The majority of cancer cells maintain a high glycolytic activity and an increased lactate production, even in a well oxygenated environment. This phenomenon is…”
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CD109 promotes the tumorigenic ability and metastatic motility of pancreatic ductal adenocarcinoma cells by Hatsuzawa, Yuuri, Yamaguchi, Kazunori, Takanashi, Tomoka, Sato, Ikuro, Tamai, Keiichi, Mochizuki, Mai, Iwai, Wataru, Wakui, Yuta, Abue, Makoto, Yamamoto, Kuniharu, Yasuda, Jun, Mizuma, Masamichi, Unno, Michiaki, Sugamura, Kazuo

“…Accumulating evidence indicates that CD109, a glycosylphosphatidylinositol-anchored glycoprotein, is highly expressed in human epithelial carcinomas of…”
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Direct peroral cholangioscopy with red dichromatic imaging 3 detected the perihilar margin of superficial papillary extension in a patient with intraductal papillary neoplasm of the bile duct by Koiwai, Akinobu, Hirota, Morihisa, Murakami, Keigo, Katayama, Tomofumi, Kin, Ryo, Endo, Katsuya, Kogure, Takayuki, Takasu, Atsuko, Sakurai, Hiroto, Kondo, Noriko, Takami, Kazuhiro, Yamamoto, Kuniharu, Katayose, Yu, Satoh, Kennichi

“…Intraductal papillary neoplasms of the bile duct (IPNB) are a tumor derived from bile duct epithelium that tends to spread laterally and non‐invasively…”
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Biliary Schwannoma That Required Differentiation from Bile Duct Cancer by Takami, Kazuhiro, Yamamoto, Kuniharu, Sakurai, Hiroto, Kondo, Noriko, Shibata, Chikashi, Katayose, Yu

“…Schwannomas are benign tumors originating from Schwann cells, which are the main component of the neural sheath. Biliary schwannomas are extremely rare. We…”
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Influence of age on postoperative complications especially pneumonia after gastrectomy for gastric cancer by Shibata, Chikashi, Ogawa, Hitoshi, Nakano, Toru, Koyama, Kaori, Yamamoto, Kuniharu, Nagao, Munenori, Takeyama, Daisuke, Takami, Kazuhiro, Yasumoto, Akihiro, Sase, Tomohiko, Kimura, Shun-Ichi, Sawada, Kentaro, Katayose, Yu

“…The aim of this study was to investigate the influence of patients' age on postoperative morbidities including pneumonia. We reviewed the clinical records of…”
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Management of common bile duct stones by Katayose, Yu, Yamamoto, Kuniharu, Takami, Kazuhiro

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Peribiliary Gland Hyperplasia That Required Differentiation from Extrahepatic Bile Duct Cancer: A Case Report by Takami, Kazuhiro, Yamamoto, Kuniharu, Sakurai, Hiroto, Sato, Yoshihiro, Kondo, Noriko, Nakano, Toru, Tsujinaka, Shingo, Koiwai, Akinobu, Hirota, Morihisa, Murakami, Keigo, Murakami, Kazuhiro, Shibata, Chikashi, Katayose, Yu

“…Abstract Introduction: The peribiliary gland is an accessory bile duct gland. Hyperplasia of these tissues may lead to elevation of the mucosa in the bile…”
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The preclinical development of regorafenib for the treatment of colorectal cancer by Miura, Koh, Satoh, Masayuki, Kinouchi, Makoto, Yamamoto, Kuniharu, Hasegawa, Yasuhiro, Philchenkov, Alex, Kakugawa, Yoichiro, Fujiya, Tsuneaki

“…The RAS-RAF-MEK-ERK pathway is one of the best characterized kinase cascades. During the exploration of small molecules that inhibit RAF1 kinase, regorafenib…”
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Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors by SATO, Ryuichiro, SUZUKI, Takashi, YAMAMOTO, Kuniharu, II, Takayuki, EGAWA, Shinichi, EVANS, Dean B, UNNO, Michiaki, SASANO, Hironobu, KATAYOSE, Yu, MIURA, Koh, SHIIBA, Kenichi, TATENO, Hiroo, MIKI, Yasuhiro, AKAHIRA, Junichi, KAMOGAWA, Yukiko, NAGASAKI, Shuji

“…Previous epidemiologic and in vitro studies have indicated a potential involvement of estrogens in the pathogenesis of human colon carcinoma, but the precise…”
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Computed Tomography Reflected Endocrine Function of the Pancreas by Sakata, Naoaki, Egawa, Shinichi, Rikiyama, Toshiki, Yoshimatsu, Gumpei, Masuda, Kunihiro, Ohtsuka, Hideo, Ottomo, Shigeru, Nakagawa, Kei, Hayashi, Hiroki, Morikawa, Takanori, Onogawa, Tohru, Yamamoto, Kuniharu, Yoshida, Hiroshi, Akada, Masanori, Motoi, Fuyuhiko, Naitoh, Takeshi, Katayose, Yu, Unno, Michiaki

“…Backgrouns/Aims There are few studies about the assessment of pancreatic function using computed tomography (CT) volumetry. In this study, we examined the…”
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The use of natural products in colorectal cancer drug discovery by Miura, Koh, Satoh, Masayuki, Kinouchi, Makoto, Yamamoto, Kuniharu, Hasegawa, Yasuhiro, Kakugawa, Yoichiro, Kawai, Masaaki, Uchimi, Kiyoshi, Aizawa, Hiroki, Ohnuma, Shinobu, Kajiwara, Taiki, Sakurai, Hiroto, Fujiya, Tsuneaki

“…Natural products (NPs) are evolutionarily designed and contain more complex and challenging structures than synthetic compounds. Since the 1980s, the…”
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Clock Gene Mouse Period2 Overexpression Inhibits Growth of Human Pancreatic Cancer Cells and Has Synergistic Effect with Cisplatin by ODA, Akira, KATAYOSE, Yu, RIKIYAMA, Toshiki, KIM, Hyunjung, CHOE, Youngshik, KIM, Kyungjin, SON, Hosun, MOTOI, Fuyuhiko, EGAWA, Shinichi, UNNO, Michiaki, YABUUCHI, Shinichi, YAMAMOTO, Kuniharu, MIZUMA, Masamichi, SHIRASOU, Satoru, ONOGAWA, Toru, OHTSUKA, Hideo, YOSHIDA, Hiroshi, HAYASHI, Hiroki

“…Circadian rhythms are the daily oscillations of multiple biological processes regulated by an endogenous clock. The Period2 gene is essential in controlling…”
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Assessment of Frey procedures: Japanese experience by Egawa, Shinichi, Motoi, Fuyuhiko, Sakata, Naoaki, Kitamura, Yo, Nakagawa, Kei, Ohtsuka, Hideo, Hayashi, Hiroki, Morikawa, Takanori, Omura, Noriyuki, Ottomo, Shigeru, Yoshida, Hiroshi, Onogawa, Toru, Yamamoto, Kuniharu, Akada, Masanori, Rikiyama, Toshiki, Katayose, Yu, Matsuno, Seiki, Unno, Michiaki

“…Background/Purpose The Frey procedure, the coring out of the pancreatic head and longitudinal pancreaticojejunostomy, is a safe, easy, and reliable method to…”
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Overexpression of Adenovirus-mediated p27kip1 Lacking the Jab1-binding Region Enhances Cytotoxicity and Inhibits Xenografted Human Cholangiocarcinoma Growth by SHIRASO, Satoru, KATAYOSE, Y. U, OHTSUKA, Hideo, MOTOI, Fuyuhiko, EGAWA, Shinichi, KATO, Junya, UNNO, Michiaki, YAMAMOTO, Kuniharu, MIZUMA, Masamichi, YABUUCHI, Shinichi, ODA, Akira, RIKIYAMA, Toshiki, ONOGAWA, Tohru, YOSHIDA, Hiroshi, HAYASHI, Hiroki

“…The cyclin-dependent kinase inhibitor (CDK1) p27 kip1 is a negative regulator of cell cycling and has antitumor effects. In our previous study, the recombinant…”
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ZD1839 (IRESSA®) Stabilizes p27Kip1 and Enhances Radiosensitivity in Cholangiocarcinoma Cell Lines by YABUUCHI, Shinichi, KATAYOSE, Yu, YOSHIDA, Hiroshi, OHTUSKA, Hideo, MOTOI, Fuyuhiko, EGAWA, Shinichi, UNNO, Michiaki, ODA, Akira, MIZUMA, Masamichi, SHIRASOU, Satoru, SASAKI, Tsuyoshi, YAMAMOTO, Kuniharu, OIKAWA, Masaya, RIKIYAMA, Toshiki, ONOGAWA, Tohru

“…The prognosis of cholangiocarcinoma patients is extremely poor despite the aggressive multidisciplinary cancer therapies that have been used clinically ( 1 )…”
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Severe cholestatic liver failure associated with gemcitabine adjuvant monotherapy for pancreatic cancer by Okada, Takaho, Egawa, Shinichi, Motoi, Fuyuhiko, Yamamoto, Kuniharu, Ottomo, Shigeru, Sakata, Naoaki, Rikiyama, Toshiki, Katayose, Yu, Unno, Michiaki

“…We report a case of severe hepatic failure caused by gemcitabine hydrochloride (GEM) monotherapy after pancreaticoduodenectomy for advanced pancreatic cancer…”
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Up-regulated p27Kip1 Reduces Matrix Metalloproteinase-9 and Inhibits Invasion of Human Breast Cancer Cells by MIZUMA, Masamichi, KATAYOSE, Yu, OHTSUKA, Hideo, MOTOI, Fuyuhiko, EGAWA, Shinichi, UNNO, Michiaki, YAMAMOTO, Kuniharu, SHIRASO, Satoru, SASAKI, Tsuyoshi, YABUUCHI, Shinichi, ODA, Akira, MASUDA, Kunihiro, RIKIYAMA, Toshiki, ONOGAWA, Tohru

“…Background: p27 Kip1 is a cyclin-dependent kinase inhibitor which has been reported to be associated with invasion, metastasis and angiogenesis in malignant…”
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