Search Results - "Yamamoto, Koichi"

Angiotensin receptor-neprilysin inhibitors: Comprehensive review and implications in hypertension treatment by Yamamoto, Koichi, Rakugi, Hiromi

“…Angiotensin receptor-neprilysin inhibitors (ARNIs) are a new class of cardiovascular agents characterized by their dual action on the major regulators of the…”
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Hypertension, the decline of activities of daily living (ADL) and frailty by Sugimoto, Ken, Yamamoto, Koichi

“…In older adults, functional decline, such as frailty and the need for nursing care, has a significant impact on quality of daily life (QOL) and life…”
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Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19 by Shibata, Shigeru, Arima, Hisatomi, Asayama, Kei, Hoshide, Satoshi, Ichihara, Atsuhiro, Ishimitsu, Toshihiko, Kario, Kazuomi, Kishi, Takuya, Mogi, Masaki, Nishiyama, Akira, Ohishi, Mitsuru, Ohkubo, Takayoshi, Tamura, Kouichi, Tanaka, Masami, Yamamoto, Eiichiro, Yamamoto, Koichi, Itoh, Hiroshi

“…Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected more than seven million people…”
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ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19 by Yamamoto, Koichi, Takeshita, Hikari, Rakugi, Hiromi

“…Angiotensin converting enzyme-2 (ACE2) is a multifunctional transmembrane protein recently recognised as the entry receptor of the virus causing COVID-19. In…”
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The future of digital hypertension management to overcome clinical inertia by Nozato, Yoichi, Yamamoto, Koichi

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Angiotensin-(1-7) as a biomarker of childhood obesity: Is there a causal relationship? by Nozato, Yoichi, Yamamoto, Koichi

“…The renin–angiotensin system (RAS) is a major regulator of cardiovascular and metabolic systems. During the last two decades, angiotensin converting enzyme…”
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Microplastics in the sediments of small-scale Japanese rivers: Abundance and distribution, characterization, sources-to-sink, and ecological risks by Kabir, A. H. M. Enamul, Sekine, Masahiko, Imai, Tsuyoshi, Yamamoto, Koichi, Kanno, Ariyo, Higuchi, Takaya

“…Microplastic pollution in small-scale river sediments remains mostly unknown. This study explored microplastics in the sediments of four small-scale Japanese…”
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Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy by Yamamuro, Tadashi, Kawabata, Tsuyoshi, Fukuhara, Atsunori, Saita, Shotaro, Nakamura, Shuhei, Takeshita, Hikari, Fujiwara, Mari, Enokidani, Yusuke, Yoshida, Gota, Tabata, Keisuke, Hamasaki, Maho, Kuma, Akiko, Yamamoto, Koichi, Shimomura, Iichiro, Yoshimori, Tamotsu

“…The systemic decline in autophagic activity with age impairs homeostasis in several tissues, leading to age-related diseases. A mechanistic understanding of…”
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Direct observation of internal state of thermal runaway in lithium ion battery during nail-penetration test by Yokoshima, Tokihiko, Mukoyama, Daikichi, Maeda, Fujio, Osaka, Tetsuya, Takazawa, Koji, Egusa, Shun, Naoi, Satomi, Ishikura, Satoru, Yamamoto, Koichi

“…A system using a high-speed and high-precision X-ray inspection system for testing internal short circuits in lithium-ion batteries (LIBs) was firstly…”
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Virus clearance by activated carbon for therapeutic monoclonal antibody purification by Kikuchi, Shinsuke, Ishihara, Takashi, Yamamoto, Koichi, Hosono, Mareto

“…•Purification process for the therapeutic mAb using an activated carbon filter was developed.•Effective virus clearance was demonstrated in the designated…”
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Novel Method for Rapid Assessment of Cognitive Impairment Using High-Performance Eye-Tracking Technology by Oyama, Akane, Takeda, Shuko, Ito, Yuki, Nakajima, Tsuneo, Takami, Yoichi, Takeya, Yasushi, Yamamoto, Koichi, Sugimoto, Ken, Shimizu, Hideo, Shimamura, Munehisa, Katayama, Taiichi, Rakugi, Hiromi, Morishita, Ryuichi

“…A rapid increase in the number of patients with dementia has emerged as a global health challenge. Accumulating evidence suggests that early diagnosis and…”
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Different effects of the deletion of angiotensin converting enzyme 2 and chronic activation of the renin-angiotensin system on muscle weakness in middle-aged mice by Takeshita, Hikari, Yamamoto, Koichi, Mogi, Masaki, Nozato, Satoko, Horiuchi, Masatsugu, Rakugi, Hiromi

“…Inhibition of the renin-angiotensin system (RAS) has been shown to alleviate muscle atrophy both under pathological conditions and during physiological aging…”
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Innovative next-generation monoclonal antibody purification using activated carbon: A challenge for flow-through and column-free processes by Ishihara, Takashi, Miyahara, Maki, Yamada, Tsuyoshi, Yamamoto, Koichi

“…Activated carbon (AC) is a porous solid with a larger surface area and lower cost than chromatography resins. AC has been used in the field of…”
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Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?-Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice by Takeshita, Hikari, Yamamoto, Koichi, Mogi, Masaki, Nozato, Satoko, Rakugi, Hiromi

“…Angiotensin converting enzyme 2 (ACE2) functions as an enzyme that produces angiotensin 1-7 (A1-7) from angiotensin II (AII) in the renin-angiotensin system…”
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Tryptophan Metabolism and COVID-19-Induced Skeletal Muscle Damage: Is ACE2 a Key Regulator? by Takeshita, Hikari, Yamamoto, Koichi

“…The severity of coronavirus disease 2019 (COVID-19) is characterized by systemic damage to organs, including skeletal muscle, due to excessive secretion of…”
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A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD by Sakaguchi, Yusuke, Hamano, Takayuki, Obi, Yoshitsugu, Monden, Chikako, Oka, Tatsufumi, Yamaguchi, Satoshi, Matsui, Isao, Hashimoto, Nobuhiro, Matsumoto, Ayumi, Shimada, Karin, Takabatake, Yoshitsugu, Takahashi, Atsushi, Kaimori, Jun-Ya, Moriyama, Toshiki, Yamamoto, Ryohei, Horio, Masaru, Yamamoto, Koichi, Sugimoto, Ken, Rakugi, Hiromi, Isaka, Yoshitaka

“…Developing strategies for managing coronary artery calcification (CAC) in patients with CKD is an important clinical challenge. Experimental studies have…”
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Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice by Takeshita, Hikari, Yamamoto, Koichi, Nozato, Satoko, Inagaki, Tadakatsu, Tsuchimochi, Hirotsugu, Shirai, Mikiyasu, Yamamoto, Ryohei, Imaizumi, Yuki, Hongyo, Kazuhiro, Yokoyama, Serina, Takeda, Masao, Oguro, Ryosuke, Takami, Yoichi, Itoh, Norihisa, Takeya, Yasushi, Sugimoto, Ken, Fukada, So-ichiro, Rakugi, Hiromi

“…The conventional forelimb grip strength test is a widely used method to assess skeletal muscle function in rodents; in this study, we modified this method to…”
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Purification of monoclonal antibodies entirely in flow-through mode by Yamada, Tsuyoshi, Yamamoto, Koichi, Ishihara, Takashi, Ohta, Shigeru

“…•An antibody purification process entirely in flow-through mode was achieved.•Buffer exchange improved the impurity clearance by depth filtration.•A…”
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Target blood pressure level for the treatment of elderly hypertensive patients: a systematic review and meta-analysis of randomized trials by Takami, Yoichi, Yamamoto, Koichi, Arima, Hisatomi, Sakima, Atsushi

“…Although recent systematic reviews (SRs) of randomized clinical trials (RCTs) support the benefit of blood pressure (BP) treatment in the elderly, the…”
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Monoclonal antibody purification using activated carbon as a replacement for Protein A affinity chromatography by Ishihara, Takashi, Miyahara, Maki, Yamamoto, Koichi

“…Activated carbon (AC) is a porous solid with a higher surface area and a lower cost than chromatography resins. AC is widely used in the pharmaceutical field…”
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