Search Results - "Yamamoto, Keiko"

Discovery of Nuclear Receptor Ligands and Elucidation of Their Mechanisms of Action by Yamamoto, Keiko

“…To develop potent ligands for the vitamin D receptor (VDR), we designed and synthesized a series of vitamin D analogues with and without 22-alkyl substituents…”
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Glass syndrome derived from chromosomal breakage downstream region of SATB2 by Shimojima Yamamoto, Keiko, Shimomura, Rina, Shoji, Hiromichi, Yamamoto, Toshiyuki

“…Glass syndrome, derived from chromosomal 2q33.1 microdeletions, manifests with intellectual disability, microcephaly, epilepsy, and distinctive features,…”
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Reciprocal chromosome translocation t(3;4)(q27;q31.2) with deletion of 3q27 and reduced FBXW7 expression in a patient with developmental delay, hypotonia, and seizures by Tamura, Takeaki, Shimojima Yamamoto, Keiko, Tohyama, Jun, Morioka, Ichiro, Kanno, Hitoshi, Yamamoto, Toshiyuki

“…Reciprocal chromosomal translocation is one of genomic variations. When cytogenetically de novo reciprocal translocations are identified in patients with some…”
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Effects of a simple method for determining the time of insemination and different methods on artificial insemination in common bottlenose dolphins (Tursiops truncatus) by YAMAMOTO, Keiko, KASHIWAGI, Nobuyuki, OTSUKA, Mika, HORI, Tatsuya

“…In this study, we examined the usefulness of a simpler and more feasible method for determining the optimal timing of artificial insemination and the…”
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A Novel SPTA1 Mutation in a Patient with Hereditary Spherocytosis without a Family History and Coexisting Gilbert's Syndrome by Nato, Yuma, Kageyama, Yuki, Suzuki, Kazutaka, Yamamoto, Keiko Shimojima, Kanno, Hitoshi, Miyashita, Hiroyuki

“…Most patients with hereditary spherocytosis (HS) have a family history of disease, while those without such a history are difficult to diagnose. We herein…”
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Interstitial microdeletions of 3q26.2q26.31 in two patients with neurodevelopmental delay and distinctive features by Tamura, Takeaki, Yamamoto Shimojima, Keiko, Shiihara, Takashi, Sakazume, Satoru, Okamoto, Nobuhiko, Yagasaki, Hiroshi, Morioka, Ichiro, Kanno, Hitoshi, Yamamoto, Toshiyuki

“…Interstitial microdeletions in the long arm of chromosome 3 are rare. In this study, we identified two patients with approximately 5‐Mb overlapping deletions…”
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Effect of Dietary Nori (Dried Laver) on Blood Pressure in Young Japanese Children: An Intervention Study by Wada, Keiko, Tsuji, Michiko, Nakamura, Kozue, Oba, Shino, Nishizawa, Sakiko, Yamamoto, Keiko, Watanabe, Kaori, Ando, Kyoko, Nagata, Chisato

“…Few studies have examined the association between seaweed intake and blood pressure in children. We conducted an intervention study to investigate whether…”
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Discovery of Nuclear Receptor Ligands and Elucidation of Their Mechanisms of Action by Keiko Yamamoto

“…To develop potent ligands for the vitamin D receptor (VDR), we designed and synthesized a series of vitamin D analogues with and without 22-alkyl substituents…”
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S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma by Chow, Kin-Hoe, Park, Hee Jung, George, Joshy, Yamamoto, Keiko, Gallup, Andrew D, Graber, Joel H, Chen, Yuanxin, Jiang, Wen, Steindler, Dennis A, Neilson, Eric G, Kim, Betty Y S, Yun, Kyuson

“…Glioma stem cells (GSC) and epithelial-mesenchymal transition (EMT) are strongly associated with therapy resistance and tumor recurrence, but the underlying…”
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Biallelic KCTD3 nonsense variant derived from paternal uniparental isodisomy of chromosome 1 in a patient with developmental epileptic encephalopathy and distinctive features by Shimojima Yamamoto, Keiko, Yoshimura, Ayumi, Yamamoto, Toshiyuki

“…A biallelic nonsense variant of the potassium channel tetramerization domain-containing protein 3 gene ( KCTD3 ) [c.1192C>T; p.R398*] was identified in a…”
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Preimplantation genetic testing using comprehensive genomic copy number analysis is beneficial for balanced translocation carriers by Yamazaki, Aya, Kuroda, Tomoko, Kawasaki, Nami, Kato, Keiichi, Shimojima Yamamoto, Keiko, Iwasa, Takeshi, Kuwahara, Akira, Taniguchi, Yuka, Takeshita, Toshiyuki, Kita, Yosuke, Mikami, Mikio, Irahara, Minoru, Yamamoto, Toshiyuki

“…Balanced chromosomal translocation is one of chromosomal variations. Carriers of balanced chromosomal translocations have an increased risk of spontaneous…”
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Switching On Depression and Potentiation in the Cerebellum by Gallimore, Andrew R., Kim, Taegon, Tanaka-Yamamoto, Keiko, De Schutter, Erik

“…Long-term depression (LTD) and long-term potentiation (LTP) in the cerebellum are important for motor learning. However, the signaling mechanisms controlling…”
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HNF4α Is a Covalent Bond-Forming Receptor by KANAMORI, Satoshi, OHASHI, Nami, ISHIDA, Hiroaki, YAMAMOTO, Keiko, ITOH, Toshimasa

“…HNF4α is a nuclear receptor whose ligands are fatty acids. HNF4α is a target molecule for drug discovery research and thus we tested its covalent binding…”
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Long‐read sequence analysis for clustered genomic copy number aberrations revealed architectures of intricately intertwined rearrangements by Tamura, Takeaki, Yamamoto Shimojima, Keiko, Okamoto, Nobuhiko, Yagasaki, Hiroshi, Morioka, Ichiro, Kanno, Hitoshi, Minakuchi, Yohei, Toyoda, Atsushi, Yamamoto, Toshiyuki

“…Most chromosomal aberrations revealed by chromosomal microarray testing (CMA) are simple; however, very complex chromosomal structural rearrangements can also…”
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Synthesis of Tetrahydrofuro[2,3-d]oxazoles and Oxazoles by Hypervalent Iodine (III)-Promoted [2 + 2 + 1] Annulation by Ishida, Hiroaki, Homma, Shoya, Kasuga, Ryota, Yamamoto, Keiko, Itoh, Toshimasa

“…Reaction of a hypervalent iodine reagent with bistriflimide efficiently promotes three-component regioselective cyclization of tetrahydrofuro[2,3-d]oxazoles…”
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Breakpoint junction analysis for complex genomic rearrangements with the caldera volcano‐like pattern by Yanagishita, Tomoe, Imaizumi, Taichi, Yamamoto‐Shimojima, Keiko, Yano, Tamami, Okamoto, Nobuhiko, Nagata, Satoru, Yamamoto, Toshiyuki

“…Chromosomal triplications can be classified into recurrent and nonrecurrent triplications. Most of the nonrecurrent triplications are embedded in duplicated…”
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Breakpoint analysis for cytogenetically balanced translocation revealed unexpected complex structural abnormalities and suggested the position effect for MEF2C by Tamura, Takeaki, Shimojima Yamamoto, Keiko, Imaizumi, Taichi, Yamamoto, Hisako, Miyamoto, Yusaku, Yagasaki, Hiroshi, Morioka, Ichiro, Kanno, Hitoshi, Yamamoto, Toshiyuki

“…Many disease‐causing genes have been identified by determining the breakpoints of balanced chromosomal translocations. Recent progress in genomic analysis has…”
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Identification of small-sized intrachromosomal segments at the ends of INV-DUP-DEL patterns by Shimojima Yamamoto, Keiko, Tamura, Takeaki, Okamoto, Nobuhiko, Nishi, Eriko, Noguchi, Atsuko, Takahashi, Ikuko, Sawaishi, Yukio, Shimizu, Masaki, Kanno, Hitoshi, Minakuchi, Yohei, Toyoda, Atsushi, Yamamoto, Toshiyuki

“…The mechanism of chromosomal rearrangement associated with inverted-duplication-deletion (INV-DUP-DEL) pattern formation has been investigated by many…”
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Structural Insights into the Loss-of-Function R288H Mutant of Human PPARγ by Egawa, Daichi, Ogiso, Taku, Nishikata, Kimina, Yamamoto, Keiko, Itoh, Toshimasa

“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor and the molecular target of thiazolidinedione-class antidiabetic drugs. It has…”
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MMX geodesy investigations: science requirements and observation strategy by Matsumoto, Koji, Hirata, Naru, Ikeda, Hitoshi, Kouyama, Toru, Senshu, Hiroki, Yamamoto, Keiko, Noda, Hirotomo, Miyamoto, Hideaki, Araya, Akito, Araki, Hiroshi, Kamata, Shunichi, Baresi, Nicola, Namiki, Noriyuki

“…In order to investigate the origin of Phobos and Deimos, the Japanese Martian Moons eXploration (MMX) mission is scheduled for launch in 2024. MMX will make…”
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