Search Results - "Yamamoto, Hirona"
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GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice
Published in Molecular psychiatry (01-07-2023)“…Large-scale genome-wide association studies (GWASs) on bipolar disorder (BD) have implicated the involvement of the fatty acid desaturase ( FADS ) locus. These…”
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Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages
Published in Nature cell biology (01-08-2020)“…Intestinal stem cells (ISCs) are located at the crypt base and fine-tune the balance of their self-renewal and differentiation 1 , 2 , but the physiological…”
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Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-07-2018)“…Brown adipose tissue is specialized to generate heat by dissipating chemical energy and may provide novel strategies for obesity treatment in humans. Recently,…”
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Topologically associating domains define the impact of de novo promoter variants on autism spectrum disorder risk
Published in Cell genomics (14-02-2024)“…Whole-genome sequencing (WGS) studies of autism spectrum disorder (ASD) have demonstrated the roles of rare promoter de novo variants (DNVs). However, most…”
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Pancreaticoduodenectomy for bile duct carcinoma of a patient undergoing hemodialysis
Published in Hepato-gastroenterology (01-01-2008)“…A 69-year-old Japanese man underwent pancreaticoduodenectomy for the resection of carcinoma at lower part of the common bile duct. Hemodialysis had already…”
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