Search Results - "Yamamoto, Hiro"

Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice by Yamamoto, Hiro, Eshima, Hiroaki, Kakehi, Saori, Kawamori, Ryuzo, Watada, Hirotaka, Tamura, Yoshifumi

“…Type 2 diabetes mellitus (T2DM) is characterized by reduced exercise tolerance due to increased fatigability in skeletal muscle. In this study, we investigated…”
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Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice by Yamamoto, Hiro-aki, Mohanan, Parayanthala V

“…The effects of ganglioside GT1b or melatonin on damage to brain mitochondrial DNA (mtDNA) and seizures induced by kainic acid were investigated both in vivo…”
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Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid by Mohanan, P.V, Yamamoto, Hiro-aki

“…The effects of kainic acid on mitochondria DNA (mtDNA) or lipid peroxidation in mice brain and, preventive effects of melatonin against its effects were…”
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Effect of α-ketoglutarate and oxaloacetate on brain mitochondrial DNA damage and seizures induced by kainic acid in mice by Yamamoto, Hiro-aki, Mohanan, Parayanthala V.

“…The effects of α-ketoglutarate and oxaloacetate on brain mitochondrial DNA (mtDNA) damage and seizures induced by kainic acid were examined both in vivo and in…”
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Effects of melatonin on paraquat or ultraviolet light exposure-induced DNA damage by Yamamoto, Hiro-aki, Mohanan, Parayanthala V.

“…The effect of paraquat or ultraviolet (UV) light exposure on calf thymus DNA was investigated in vitro. When paraquat (0.1, 0.25, 0.5, or 1.0 mM) was incubated…”
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Melatonin attenuates L-cysteine-induced seizures and lipid peroxidation in the brain of mice by Yamamoto, H, Tang, H

“…The effect of melatonin, a potent free radical scavenger, on L-cysteine-induced seizures and lipid peroxidation was investigated in mice. When L-cysteine…”
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In Vivo and in Vitro Effects of Melatonin or Ganglioside GT1B on L-Cysteine–Induced Brain Mitochondrial DNA Damage in Mice by Yamamoto, Hiro-aki, Mohanan, Parayanthala V.

“…The effects of L-cysteine on mitochondrial DNA (mtDNA) in mouse brain were investigated both in vivoandin vitro. An intracerebroventricular (icv) injection of…”
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Preventive effect of melatonin against cyanide-induced seizures and lipid peroxidation in mice by Yamamoto, Hiro-aki, Tang, Hai-wang

“…Subcutaneous injection of potassium cyanide (6, 8, and 9 mg/kg) caused a severe tonic seizure in a dose-dependent manner. However, the incidence of seizures…”
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Melatonin attenuates brain mitochondria DNA damage induced by potassium cyanide in vivo and in vitro by Yamamoto, Hiro-aki, Mohanan, Parayanthala V

“…The effect of potassium cyanide on mitochondria DNA (mtDNA) in mouse brain was investigated in vivo and in vitro. When potassium cyanide (0, 0.1, 1.0 or 2.0…”
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Neurotoxic similarity between kainate and cyanide by Yamamoto, Hiro-aki

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Preventive effect of melatonin against DNA damage induced by cyanide, kainate, glutathione/Fe3+/O2, or H2O2/Fe2 by Yamamoto, Hiro-aki, Mohanan, Parayanthala V.

“…We have investigated hydroxyl free radical (⋅OH)‐mediated damage to calf thymus DNA produced by potassium cyanide, kainate, H2O2/Fe2+, or glutathione/Fe3+ by…”
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Antagonistic effect of melatonin against cyanide-induced seizures and acute lethality in mice by Yamamoto, Hiro-aki, Tang, Hai-wang

“…The effect of melatonin on potassium cyanide-induced neurotoxicity was investigated in vivo. The ED 50 value of potassium cyanide, a;5 measured by induction of…”
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A hypothesis for cyanide-induced tonic seizures with supporting evidence by Yamamoto, Hiro-aki

“…A possible relationship among cyanide-induced convulsions, calmodulin, nitric oxide and protein kinase C was investigated in mice. The ED 50 value of cyanide…”
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Effect of piperonyl butoxide or allopurinol on cyanide-induced lipid peroxidation in mouse brain by Yamamoto, Hiro-aki

“…The effect of piperonyl butoxide or allopurinol on cyanide-induced lipid peroxidation was investigated using homogenates from whole brain of mice. The brain…”
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Infrared Spectroscopy and Temperature-Programmed Desorption Study of Adsorbed Thiophene on γ-Al2O3 by Quigley, Wes W. C, Yamamoto, Hiro D, Aegerter, Paul A, Simpson, Garth J, Bussell, Mark E

“…The adsorption of thiophene (C4H4S) on γ-Al2O3 has been investigated in ultrahigh vacuum (UHV) using infrared (IR) spectroscopy and temperature-programmed…”
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Fatty acids including alpha‐ketoglutarate, citrate, malate, fumarate, oxaloacetate, pyruvate, and succinate inhibit neurotoxicity induced by potassium cyanide in mice by Yamamoto, Hiro‐aki

“…When potassium cyanide (7mg/kg) was injected subcutaneously to mice, it was observed broad‐spectrum limbic and severe sustained seizures in 100 % of the…”
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Effect of atropine on cyanide-induced acute lethality in mice by Yamamoto, Hiro-aki

“…The effects of atropine on acute lethality induced by cyanide were investigated in mice. The LD 50 value of cyanide (s.c. injection) was 8.4 (7.6–9.3) mg/kg…”
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Effect of melatonin, piperonyl butoxide, or cobalt chloride on l-cysteine-induced lipid peroxidation in homogenate from whole brain of mice by Yamamoto, Hiro-aki, Tang, Hai-wang

“…Brain homogenates exposed to a low concentration of l-cysteine (0.05, 0.1, 0.5, 1.0, and 2.0 mM) were significantly increased in their concentration of…”
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Protection against cyanide-induced convulsions with alpha-ketoglutarate by Yamamoto, H

“…Protection against convulsions induced by cyanide was observed after treatment with alpha-ketoglutarate, either alone or in combination with sodium…”
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TCA cycle may play an important role for protection against kainic acid-induced neurotoxicity in mice by Yamamoto, Hiro-aki

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