Search Results - "Yamamoto, Hideaki"

Biological neurons act as generalization filters in reservoir computing by Sumi, Takuma, Yamamoto, Hideaki, Katori, Yuichi, Ito, Koki, Moriya, Satoshi, Konno, Tomohiro, Sato, Shigeo, Hirano-Iwata, Ayumi

“…Reservoir computing is a machine learning paradigm that transforms the transient dynamics of high-dimensional nonlinear systems for processing time-series…”
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NPC1L1 Facilitates Sphingomyelin Absorption and Regulates Diet-Induced Production of VLDL/LDL-associated S1P by Yamanashi, Yoshihide, Takada, Tappei, Yamamoto, Hideaki, Suzuki, Hiroshi

“…Niemann-Pick C1-Like 1 (NPC1L1) is a cholesterol importer and target of ezetimibe, a cholesterol absorption inhibitor used clinically for dyslipidemia. Recent…”
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A single-cell based hybrid neuronal network configured by integration of cell micropatterning and dynamic patch-clamp by Yamamoto, Hideaki, Hayakawa, Takeshi, Netoff, Theoden I., Hirano-Iwata, Ayumi

“…We integrate cell micropatterning technology with dynamic clamp electrophysiology to realize a hybrid neuronal network of biological and computational neurons…”
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Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice by Yamamoto, Hideaki, Yamanashi, Yoshihide, Takada, Tappei, Mu, Shuang, Tanaka, Yusuke, Komine, Toko, Suzuki, Hiroshi

“…Westernization of dietary habits increases lipid intake and is responsible for increased numbers of patients with atherosclerotic diseases. Niemann-Pick…”
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Summary of temporal changes in air dose rates and radionuclide deposition densities in the 80 km zone over five years after the Fukushima Nuclear Power Plant accident by Saito, Kimiaki, Mikami, Satoshi, Andoh, Masaki, Matsuda, Norihiro, Kinase, Sakae, Tsuda, Shuichi, Yoshida, Tadayoshi, Sato, Tetsuro, Seki, Akiyuki, Yamamoto, Hideaki, Sanada, Yukihisa, Wainwright-Murakami, Haruko, Takemiya, Hiroshi

“…We summarized temporal changes in air dose rates and radionuclide deposition densities over five years in the 80 km zone based on large-scale environmental…”
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NPC1L1 is a key regulator of intestinal vitamin K absorption and a modulator of warfarin therapy by Takada, Tappei, Yamanashi, Yoshihide, Konishi, Kentaro, Yamamoto, Takehito, Toyoda, Yu, Masuo, Yusuke, Yamamoto, Hideaki, Suzuki, Hiroshi

“…Vitamin K (VK) is a micronutrient that facilitates blood coagulation. VK antagonists, such as warfarin, are used in the clinic to prevent thromboembolism…”
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Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks by Sato, Yuya, Yamamoto, Hideaki, Kato, Hideyuki, Tanii, Takashi, Sato, Shigeo, Hirano-Iwata, Ayumi

“…Neuronal networks in dissociated culture combined with cell engineering technology offer a pivotal platform to constructively explore the relationship between…”
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VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body by Yamamoto, Hideaki, Takada, Tappei, Yamanashi, Yoshihide, Ogura, Masatsune, Masuo, Yusuke, Harada-Shiba, Mariko, Suzuki, Hiroshi

“…Only free drugs have been believed to be carried into tissues through active or passive transport. However, considering that lipoproteins function as carriers…”
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Polydimethylsiloxane microfluidic films for in vitro engineering of small-scale neuronal networks by Takemuro, Taiki, Yamamoto, Hideaki, Sato, Shigeo, Hirano-Iwata, Ayumi

“…Polydimethylsiloxane microfluidic devices have become standard tools in cell engineering research. However, through-holes where cells access the microchannels…”
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Computational Efficiency of a Modular Reservoir Network for Image Recognition by Dai, Yifan, Yamamoto, Hideaki, Sakuraba, Masao, Sato, Shigeo

“…Liquid state machine (LSM) is a type of recurrent spiking network with a strong relationship to neurophysiology and has achieved great success in time series…”
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Dependence and Homeostasis of Membrane Impedance on Cell Morphology in Cultured Hippocampal Neurons by Matsumura, Ryosuke, Yamamoto, Hideaki, Hayakawa, Takeshi, Katsurabayashi, Shutaro, Niwano, Michio, Hirano-Iwata, Ayumi

“…The electrical impedance of cell membranes is important for excitable cells, such as neurons, because it strongly influences the amount of membrane potential…”
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Mechanically stable solvent-free lipid bilayers in nano- and micro-tapered apertures for reconstitution of cell-free synthesized hERG channels by Tadaki, Daisuke, Yamaura, Daichi, Araki, Shun, Yoshida, Miyu, Arata, Kohei, Ohori, Takeshi, Ishibashi, Ken-ichi, Kato, Miki, Ma, Teng, Miyata, Ryusuke, Tozawa, Yuzuru, Yamamoto, Hideaki, Niwano, Michio, Hirano-Iwata, Ayumi

“…The self-assembled bilayer lipid membrane (BLM) is the basic component of the cell membrane. The reconstitution of ion channel proteins in artificially formed…”
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Impact of modular organization on dynamical richness in cortical networks by Yamamoto, Hideaki, Moriya, Satoshi, Ide, Katsuya, Hayakawa, Takeshi, Akima, Hisanao, Sato, Shigeo, Kubota, Shigeru, Tanii, Takashi, Niwano, Michio, Teller, Sara, Soriano, Jordi, Hirano-Iwata, Ayumi

“…As in many naturally formed networks, the brain exhibits an inherent modular architecture that is the basis of its rich operability, robustness, and…”
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Differential neurite outgrowth is required for axon specification by cultured hippocampal neurons by Yamamoto, Hideaki, Demura, Takanori, Morita, Mayu, Banker, Gary A., Tanii, Takashi, Nakamura, Shun

“…Formation of an axon is the first morphological evidence of neuronal polarization, visible as a profound outgrowth of the axon compared with sibling neurites…”
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Neuraminidase-Dependent Degradation of Polysialic Acid Is Required for the Lamination of Newly Generated Neurons by Sajo, Mari, Sugiyama, Hiroki, Yamamoto, Hideaki, Tanii, Takashi, Matsuki, Norio, Ikegaya, Yuji, Koyama, Ryuta

“…Hippocampal granule cells (GCs) are generated throughout the lifetime and are properly incorporated into the innermost region of the granule cell layer (GCL)…”
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Micro- and Nano-Technologies for Lipid Bilayer-Based Ion-Channel Functional Assays by Hirano-Iwata, Ayumi, Ishinari, Yutaka, Yamamoto, Hideaki, Niwano, Michio

“…Ion channel proteins provide gated pores that allow ions to passively flow across cell membranes. Owing to their crucial roles in regulating transmembrane ion…”
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Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain by Yamamoto, Hideaki, Maruo, Tomohiko, Majima, Takashi, Ishizaki, Hiroyoshi, Tanaka-Okamoto, Miki, Miyoshi, Jun, Mandai, Kenji, Takai, Yoshimi

“…Adherens junctions (AJs) play a role in mechanically connecting adjacent cells to maintain tissue structure, particularly in epithelial cells. The major…”
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Amphiphobic Septa Enhance the Mechanical Stability of Free-Standing Bilayer Lipid Membranes by Yamaura, Daichi, Tadaki, Daisuke, Araki, Shun, Yoshida, Miyu, Arata, Kohei, Ohori, Takeshi, Ishibashi, Ken-ichi, Kato, Miki, Ma, Teng, Miyata, Ryusuke, Yamamoto, Hideaki, Tero, Ryugo, Sakuraba, Masao, Ogino, Toshio, Niwano, Michio, Hirano-Iwata, Ayumi

“…Artificial bilayer lipid membranes (BLMs) provide well-defined systems for investigating the fundamental properties of membrane proteins, including ion…”
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Live-Cell, Label-Free Identification of GABAergic and Non-GABAergic Neurons in Primary Cortical Cultures Using Micropatterned Surface by Kono, Sho, Yamamoto, Hideaki, Kushida, Takatoshi, Hirano-Iwata, Ayumi, Niwano, Michio, Tanii, Takashi

“…Excitatory and inhibitory neurons have distinct roles in cortical dynamics. Here we present a novel method for identifying inhibitory GABAergic neurons from…”
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Characterization of genetically engineered mouse hepatoma cells with inducible liver functions by overexpression of liver-enriched transcription factors by Yamamoto, Hideaki, Tonello, Jane Marie, Sambuichi, Takanori, Kawabe, Yoshinori, Ito, Akira, Kamihira, Masamichi

“…New cell sources for the research and therapy of organ failure could significantly alleviate the shortage of donor livers that are available to patients who…”
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