Search Results - "Yamaguchi, Yukie"

Drug allergy and autoimmune diseases by Watanabe, Yuko, Yamaguchi, Yukie

“…Systemic autoimmune diseases are reportedly associated with a high frequency of drug allergies. In particular, systemic lupus erythematosus (SLE), Sjögren's…”
Get full text

Periostin in skin tissue and skin-related diseases by Yamaguchi, Yukie

“…Extracellular matrix (ECM) is not only involved in the maintenance of normal physiological tissue but also in interactions with other ECM components, tissue…”
Get full text

Cutaneous manifestations associated with immune checkpoint inhibitors by Watanabe, Tomoya, Yamaguchi, Yukie

“…Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block key mediators of tumor-mediated immune evasion. The frequency of its use has increased…”
Get full text

Involvement of caveolin-1 in skin diseases by Takamura, Naoko, Yamaguchi, Yukie

“…The skin is the outermost layer and largest organ in the human body. Since the skin interfaces with the environment, it has a variety of roles, including…”
Get full text

Abnormal inflammatory traits and downregulated caveolin-1 expression in monocytes of psoriasis patients may be associated with psoriatic inflammation and atherosclerosis by Asami, Miho, Ototake, Yasushi, Takamura, Naoko, Watanabe, Yuko, Aihara, Michiko, Yamaguchi, Yukie

“…BACKGROUNDMonocytes and macrophages are implicated in inflammation and atherosclerosis, whereas monocytes are involved in psoriasis lesion formation. We…”
Get full text

Toxic epidermal necrolysis accompanied by several immune-related adverse events developed after discontinuation of nivolumab by Watanabe, Yuko, Yamaguchi, Yukie, Takamura, Naoko, Takahashi, Yukitoshi, Aihara, Michiko

Get full text

Exploring the deeper linkage between adverse drug reactions and autoimmune diseases by Yamaguchi, Yukie

Get full text

Long‐term safety of brodalumab in Japanese patients with plaque psoriasis: An open‐label extension study by Yamaguchi, Yukie, Takatsu, Nobumichi, Ootaki, Kenji, Nakagawa, Hidemi

“…Brodalumab, an interleukin‐17 receptor A inhibitor, demonstrated rapid and robust efficacy with a favorable safety profile in patients with moderate to severe…”
Get full text

Expression profile of periostin isoforms in systemic sclerosis by Nanri, Yasuhiro, Nunomura, Satoshi, Watanabe, Tomoya, Ohta, Shoichiro, Yamaguchi, Yukie, Izuhara, Kenji

Get full text

A water-soluble caveolin-1 peptide inhibits psoriasis-like skin inflammation by suppressing cytokine production and angiogenesis by Asai, Chika, Takamura, Naoko, Watanabe, Tomoya, Asami, Miho, Ikeda, Noriko, Reese, Charles F., Hoffman, Stanley, Yamaguchi, Yukie

“…The plasma membrane protein caveolin-1 (CAV-1) regulates signaling by inhibiting a wide range of kinases and other enzymes. Our previous study demonstrated…”
Get full text

Clinical features of patients with systemic sclerosis positive for anti-SS-A antibody: a cohort study of 156 patients by Watanabe, Tomoya, Ototake, Yasushi, Akita, Asami, Suzuki, Mao, Kanaoka, Miwa, Tamura, Jun, Saigusa, Yusuke, Yamaguchi, Yukie

“…Anti-SS-A/Ro antibody (anti-SSA), the diagnostic marker of Sjögren's syndrome (SS), is often detected in systemic sclerosis (SSc). Some patients are diagnosed…”
Get full text

The nationwide epidemiological survey of Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan, 2016-2018 by Sunaga, Yuma, Kurosawa, Michiko, Ochiai, Hirotaka, Watanabe, Hideaki, Sueki, Hirohiko, Azukizawa, Hiroaki, Asada, Hideo, Watanabe, Yuko, Yamaguchi, Yukie, Aihara, Michiko, Mizukawa, Yoshiko, Ohyama, Manabu, Hama, Natsumi, Abe, Riichiro, Hashizume, Hideo, Nakajima, Saeko, Nomura, Takashi, Kabashima, Kenji, Tohyama, Mikiko, Takahashi, Hayato, Mieno, Hiroki, Ueta, Mayumi, Sotozono, Chie, Niihara, Hiroyuki, Morita, Eishin, Kokaze, Akatsuki

“…•Estimated Yearly prevalence per million was 2.5 for SJS and 1 for TEN.•Mean age was 53.9 years for SJS, and 61.8 years for TEN.•Mortality rate was 4.1 % for…”
Get full text

Downregulated Caveolin-1 expression in circulating monocytes may contribute to the pathogenesis of psoriasis by Takamura, Naoko, Yamaguchi, Yukie, Watanabe, Yuko, Asami, Miho, Komitsu, Noriko, Aihara, Michiko

“…Caveolin-1 (CAV-1) is the principal component of caveolae that regulates a variety of signaling molecules and receptors. Our previous study revealed CAV-1…”
Get full text

Periostin plays a critical role in the cell cycle in lung fibroblasts by Yoshihara, Tomohito, Nanri, Yasuhiro, Nunomura, Satoshi, Yamaguchi, Yukie, Feghali-Bostwick, Carol, Ajito, Keiichi, Murakami, Shoichi, Mawatari, Masaaki, Izuhara, Kenji

“…Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a median survival of only three to 5 years. Fibroblast proliferation is a hallmark of IPF as…”
Get full text

Serum levels of C‐C motif chemokine ligand 2 and interleukin‐8 as possible biomarkers in patients with toxic epidermal necrolysis accompanied by acute respiratory distress syndrome by Watanabe, Tomoya, Watanabe, Yuko, Ikeda, Noriko, Aihara, Michiko, Yamaguchi, Yukie

“…Toxic epidermal necrolysis (TEN) is a fatal cutaneous adverse reaction that occasionally affects multiple organs. Acute respiratory distress syndrome (ARDS) is…”
Get full text

Anti-inflammatory effect of collagen tripeptide in atopic dermatitis by Hakuta, Amiko, Yamaguchi, Yukie, Okawa, Tomoko, Yamamoto, Shoko, Sakai, Yasuo, Aihara, Michiko

“…•Collagen tripeptide suppressed type 2 cytokine and chemokine production from keratinocytes.•STAT1 is involved in suppressing inflammatory chemokines during…”
Get full text

Retrospective analysis of Stevens–Johnson syndrome and toxic epidermal necrolysis in 87 Japanese patients – Treatment and outcome by Yamane, Yumiko, Matsukura, Setsuko, Watanabe, Yuko, Yamaguchi, Yukie, Nakamura, Kazuko, Kambara, Takeshi, Ikezawa, Zenro, Aihara, Michiko

“…Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe adverse drug reactions with high mortality. To present the clinical…”
Get full text

Decreased Expression of Caveolin-1 Contributes to the Pathogenesis of Psoriasiform Dermatitis in Mice by Yamaguchi, Yukie, Watanabe, Yuko, Watanabe, Tomoya, Komitsu, Noriko, Aihara, Michiko

“…Psoriasis is a chronic inflammatory skin disease characterized by excessive proliferation and abnormal keratinocyte development, in which T helper type 17…”
Get full text

Mortality and risk factors on admission in toxic epidermal necrolysis: A cohort study of 59 patients by Watanabe, Tomoya, Go, Hirofumi, Saigusa, Yusuke, Takamura, Naoko, Watanabe, Yuko, Yamane, Yumiko, Totsuka, Michiru, Ishikawa, Hideyuki, Nakamura, Kazuko, Matsukura, Setsuko, Kambara, Takeshi, Takaki, Shunsuke, Yamaguchi, Yukie, Aihara, Michiko

“…Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening disorders characterized by widespread epidermal necrosis of…”
Get full text

Periostin in Skin Tissue and Skin-Related Diseases by Yamaguchi, Yukie

“…[ABSTRACT] Extracellular matrix (ECM) is not only involved in the maintenance of normal physiological tissue but also in interactions with other ECM…”
Get full text