Search Results - "Yamaguchi, Taizo"

Initial Experience of Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma in Real-World Clinical Practice by Iwamoto, Hideki, Shimose, Shigeo, Noda, Yu, Shirono, Tomotake, Niizeki, Takashi, Nakano, Masahito, Okamura, Shusuke, Kamachi, Naoki, Suzuki, Hiroyuki, Sakai, Miwa, Kajiwara, Akira, Itano, Satoshi, Tanaka, Masatoshi, Yamaguchi, Taizo, Kuromatsu, Ryoko, Koga, Hironori, Torimura, Takuji

“…Background: Atezolizumab plus bevacizumab was approved for patients with hepatocellular carcinoma (HCC). Although clinical trials have revealed its efficacy,…”
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Controlling Nutritional Status (CONUT) Score is Associated with Overall Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib: A Multicenter Cohort Study by Shimose, Shigeo, Kawaguchi, Takumi, Iwamoto, Hideki, Tanaka, Masatoshi, Miyazaki, Ken, Ono, Miki, Niizeki, Takashi, Shirono, Tomotake, Okamura, Shusuke, Nakano, Masahito, Suga, Hideya, Yamaguchi, Taizo, Yokokura, Yoshinori, Noguchi, Kazunori, Koga, Hironori, Torimura, Takuji

“…We aimed to investigate the impact of the controlling nutritional status (CONUT) score, an immuno-nutritional biomarker, on the prognosis of patients with…”
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Weekends-Off Lenvatinib for Unresectable Hepatocellular Carcinoma Improves Therapeutic Response and Tolerability toward Adverse Events by Iwamoto, Hideki, Suzuki, Hiroyuki, Shimose, Shigeo, Niizeki, Takashi, Nakano, Masahito, Shirono, Tomotake, Okamura, Shusuke, Noda, Yu, Kamachi, Naoki, Nakamura, Toru, Masuda, Atsutaka, Sakaue, Takahiko, Tanaka, Toshimitsu, Nakano, Dan, Sakai, Miwa, Yamaguchi, Taizo, Kuromatsu, Ryoko, Koga, Hironori, Torimura, Takuji

“…Although lenvatinib has become the standard therapy for hepatocellular carcinoma (HCC), the high incidence rate of adverse events (AEs) is an issue. This study…”
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Deterioration of liver function and aging disturb sequential systemic therapy for unresectable hepatocellular carcinoma by Shimose, Shigeo, Hiraoka, Atsushi, Tanaka, Masatoshi, Iwamoto, Hideki, Tanaka, Takaaki, Noguchi, Kazunori, Aino, Hajime, Yamaguchi, Taizo, Itano, Satoshi, Suga, Hideya, Niizeki, Takashi, Moriyama, Etsuko, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Nakano, Masahito, Kawaguchi, Takumi, Kuromatsu, Ryoko, Koga, Hironori, Torimura, Takuji

“…This study aimed to investigate the clinical characteristics of patients with unresectable hepatocellular carcinoma (HCC), who were eligible for sequential…”
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Feasibility and safety of a novel indwelling catheter system via the femoral artery for intermittent transarterial therapy for treating malignant liver tumors by Iwamoto, Hideki, Itano, Satoshi, Itano, Osamu, Ishii, Masatsugu, Niizeki, Takashi, Shirono, Tomotake, Shimose, Shigeo, Suzuki, Hiroyuki, Kajiwara, Akira, Yamaguchi, Taizo, Koga, Hironori, Torimura, Takuji

“…Purpose An indwelling arterial access system via the brachial artery, System-i, has been previously reported. We have modified the technique for the femoral…”
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Case Report: Exacerbation of varices following atezolizumab plus bevacizumab treatment of hepatocellular carcinoma: A case series and literature review by Suzuki, Hiroyuki, Iwamoto, Hideki, Shimose, Shigeo, Niizeki, Takashi, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Yamaguchi, Taizo, Nakano, Masahito, Kuromatsu, Ryoko, Koga, Hironori, Kawaguchi, Takumi

“…Recently, a combined regimen of atezolizumab and bevacizumab (AB) treatment has been approved as a first-line treatment in patients with advanced…”
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Survival Benefit of Hepatic Arterial Infusion Chemotherapy over Sorafenib in the Treatment of Locally Progressed Hepatocellular Carcinoma by Iwamoto, Hideki, Niizeki, Takashi, Nagamatsu, Hiroaki, Ueshima, Kazuomi, Nomura, Takako, Kuzuya, Teiji, Kasai, Kazuhiro, Kooka, Yohei, Hiraoka, Atsushi, Sugimoto, Rie, Yonezawa, Takehiro, Ishihara, Akio, Deguchi, Akihiro, Arai, Hirotaka, Shimose, Shigeo, Shirono, Tomotake, Nakano, Masahito, Okamura, Shusuke, Noda, Yu, Kamachi, Naoki, Sakai, Miwa, Suzuki, Hiroyuki, Aino, Hajime, Matsukuma, Norito, Matsugaki, Satoru, Ogata, Kei, Yano, Yoichi, Ueno, Takato, Kajiwara, Masahiko, Itano, Satoshi, Fukuizumi, Kunitaka, Kawano, Hiroshi, Noguchi, Kazunori, Tanaka, Masatoshi, Yamaguchi, Taizo, Kuromatsu, Ryoko, Kawaguchi, Atsushi, Koga, Hironori, Torimura, Takuji, New Fp Study Group, Kurume Liver Cancer Study Group Of Japan

“…Not all patients with hepatocellular carcinoma (HCC) benefit from treatment with molecular targeted agents such as sorafenib. We investigated whether New-FP…”
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First‐line sorafenib sequential therapy and liver disease etiology for unresectable hepatocellular carcinoma using inverse probability weighting: A multicenter retrospective study by Shimose, Shigeo, Hiraoka, Atsushi, Nakano, Masahito, Iwamoto, Hideki, Tanaka, Masatoshi, Tanaka, Takaaki, Noguchi, Kazunori, Aino, Hajime, Ogata, Kei, Kajiwara, Masahiko, Itano, Satoshi, Yokokura, Yoshinori, Yamaguchi, Taizo, Kawano, Hiroshi, Matsukuma, Norito, Suga, Hideya, Niizeki, Takashi, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Kawaguchi, Takumi, Koga, Hironori, Torimura, Takuji

“…Background and Aims Sequential therapy with molecular‐targeted agents (MTAs) is considered effective for unresectable hepatocellular carcinoma (HCC) patients…”
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High glucose activates rat pancreatic stellate cells through protein kinase C and p38 mitogen-activated protein kinase pathway by Nomiyama, Yoko, Tashiro, Mitsuo, Yamaguchi, Taizo, Watanabe, Shiro, Taguchi, Masashi, Asaumi, Hiroshi, Nakamura, Hayato, Otsuki, Makoto

“…Hyperglycemia is implicated in fibrosis in many organs. Exocrine and endocrine pancreas are closely linked both anatomically and physiologically, and…”
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Animal Models of Chronic Pancreatitis by Otsuki, Makoto, Yamaguchi, Taizo, Yamamoto, Mitsuyoshi

“…Animal models for CP in rats can be classified into 2 groups: one is noninvasive or nonsurgical models and the other is invasive or surgical models. Pancreatic…”
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Induction of PDX-1-positive cells in the main duct during regeneration after acute necrotizing pancreatitis in rats by Taguchi, Masashi, Yamaguchi, Taizo, Otsuki, Makoto

“…Pancreatic regeneration involves two pathways; proliferation and differentiation of pancreatic progenitor cells, which probably exist in pancreatic ductal…”
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Clinical Significance of Adverse Events for Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib: A Multicenter Retrospective Study by Shimose, Shigeo, Iwamoto, Hideki, Niizeki, Takashi, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Nakano, Masahito, Suga, Hideya, Kuromatsu, Ryoko, Yamaguchi, Taizo, Kawaguchi, Takumi, Tanaka, Masatoshi, Noguchi, Kazunori, Koga, Hironori, Torimura, Takuji

“…We sought to investigate the clinical profile(s) associated with the discontinuation of lenvatinib (LEN) due to severe adverse events (DLSAE) in patients with…”
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Long-term overexpression of membrane type-1 matrix metalloproteinase and matrix metalloproteinase-2 in oleic acid-induced pancreatitis in rats by YAMAGUCHI, Taizo, NAKAMURA, Hayato, KIHARA, Yasuyuki, TAGUCHI, Masashi, YOSHIKAWA, Hiroyuki, OTSUKI, Makoto

“…The matrix metalloproteinase (MMP) plays important roles in extracellular matrix turnover. However, little is known about the roles of MMP-2 and type IV…”
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Alternating Lenvatinib and Trans-Arterial Therapy Prolongs Overall Survival in Patients with Inter-Mediate Stage HepatoCellular Carcinoma: A Propensity Score Matching Study by Shimose, Shigeo, Iwamoto, Hideki, Tanaka, Masatoshi, Niizeki, Takashi, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Nakano, Masahito, Suga, Hideya, Yamaguchi, Taizo, Kawaguchi, Takumi, Kuromatsu, Ryoko, Noguchi, Kazunori, Koga, Hironori, Torimura, Takuji

“…We aimed to evaluate the impact of alternating lenvatinib (LEN) and trans-arterial therapy (AT) in patients with intermediate-stage hepatocellular carcinoma…”
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Oleic acid-induced Pancreatitis alters expression of transforming growth factor-β1 and Extracellular matrix components in rats by TASHIRO, Mitsuo, NAKAMURA, Hayato, TAGUCHI, Masashi, YAMAGUCHI, Taizo, YOSHIKAWA, Hiroyuki, FUKUMITSU, Ken-Ichiro, KIHARA, Yasuyuki, OTSUKI, Makoto

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Lenvatinib prolongs the progression‑free survival time of patients with intermediate‑stage hepatocellular carcinoma refractory to transarterial chemoembolization: A multicenter cohort study using data mining analysis by Shimose, Shigeo, Kawaguchi, Takumi, Tanaka, Masatoshi, Iwamoto, Hideki, Miyazaki, Ken, Moriyama, Etsuko, Suzuki, Hiroyuki, Niizeki, Takashi, Shirono, Tomotake, Nakano, Masahito, Suga, Hideya, Yamaguchi, Taizo, Yokokura, Yoshinori, Noguchi, Kazunori, Koga, Hironori, Torimura, Takuji

“…Tyrosine kinase inhibitors are considered for use in patients with hepatocellular carcinoma (HCC) refractory to transarterial chemoembolization (TACE). The aim…”
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How, Why and Where it Hurts—Breaking Down Pain Syndrome Among Nursing Home Patients With Dementia: A Cross-Sectional Analysis of the COSMOS Trial by Wagatsuma, Shunta, Yamaguchi, Taizo, Berge, Line I., Husebo, Bettina, Habiger, Torstein F., Nouchi, Rui, Angeles, Renira C.

“…Between 40%-60% of nursing home patients with dementia suffer from chronic and acute pain despite increasing their analgesic drug prescription. Determine the…”
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Mo1051 The Effectiveness of Angiographic Subsegmentectomy As a Treatment Method Using the Hemodynamics of Hepatocellular Carcinoma by Iwamoto, Shozo, Yamaguchi, Taizo, Hongo, Osamu, Iwamoto, Hideki

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Excellent Outcomes With Angiographic Subsegmentectomy in the Treatment of Typical Hepatocellular Carcinoma: A Retrospective Study of Local Recurrence and Long-Term Survival Rates in 120 Patients With Hepatocellular Carcinoma by IWAMOTO, Shozo, YAMAGUCHI, Taizo, HONGO, Osamu, IWAMOTO, Hideki, SANEFUJI, Hayato

“…The authors successfully adopted an interesting and effective treatment for hepatocellular carcinoma (HCC) referred to as angiographic subsegmentectomy (AS)…”
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Transient Stasis of Pancreatic Fluid Flow Together with Mild Injury of the Pancreatic Duct Cause Chronic Pancreatitis by Yamaguchi, Taizo, Kihara, Yasuyuki, Yamamoto, Mitsuyoshi, Otsuki, Makoto

“…Background Little is known about the etiopathogenesis of chronic pancreatitis, due mainly to the lack of simple animal models suitable to study inflammatory…”
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