Search Results - "Yamagata, Ryota"

Angiotensin (1–7) Attenuates the Nociceptive Behavior Induced by Substance P and NMDA via Spinal MAS1 by Yamagata, Ryota, Nemoto, Wataru, Fujita, Maho, Nakagawasai, Osamu, Tan-No, Koichi

“…The intrathecal (i.t.) injection of substance P (SP) and N-methyl-D-aspartate (NMDA) induce transient nociceptive response by activating neurokinin (NK) 1 and…”
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Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice by Nemoto, Wataru, Yamagata, Ryota, Nakagawasai, Osamu, Nakagawa, Koharu, Hung, Wan-Yi, Fujita, Maho, Tadano, Takeshi, Tan-No, Koichi

“…We have previously demonstrated that the phosphorylation of p38 MAPK, through spinal AT1 receptor activation, is involved in formalin-induced nociception and…”
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Methylmercury Induces Apoptosis in Mouse C17.2 Neural Stem Cells through the Induction of OSGIN1 Expression by NRF2 by Yamashita, Naoya, Uchiyama, Marino, Yamagata, Ryota, Hwang, Gi-Wook

“…Methylmercury is a known environmental pollutant that exhibits severe neurotoxic effects. However, the mechanism by which methylmercury causes neurotoxicity…”
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Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice by Nakagawasai, Osamu, Takahashi, Kohei, Koyama, Taisei, Yamagata, Ryota, Nemoto, Wataru, Tan-No, Koichi

“…Angiotensin (Ang)-converting-enzyme (ACE) 2 converts Ang II into Ang (1-7), which in turn acts on MAS receptors (ACE2/Ang (1-7)/MAS receptors pathway). This…”
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Angiotensin-Related Peptides and Their Role in Pain Regulation by Nemoto, Wataru, Yamagata, Ryota, Nakagawasai, Osamu, Tan-No, Koichi

“…Angiotensin (Ang)-generating system has been confirmed to play an important role in the regulation of fluid balance and blood pressure and is essential for the…”
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Anti‐hypersensitive effect of angiotensin (1‐7) on streptozotocin‐induced diabetic neuropathic pain in mice by Ogata, Yoshiki, Nemoto, Wataru, Yamagata, Ryota, Nakagawasai, Osamu, Shimoyama, Shuji, Furukawa, Tomonori, Ueno, Shinya, Tan‐No, Koichi

“…Background We have recently reported that the spinal angiotensin (Ang) converting enzyme (ACE)/Ang II/AT1 receptor axis and downstream p38 MAPK phosphorylation…”
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Methylmercury exposure at dosage conditions that do not affect growth can impair memory in adolescent mice by Yamagata, Ryota, Saito, Ai, Fukushima, Ryoko, Nakagawasai, Osamu, Yamashita, Naoya, Tan-No, Koichi, Hwang, Gi-Wook

“…Methylmercury is an environmental pollutant that can induce serious central nervous system damage. Its ubiquitous presence in the environment in trace amounts…”
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A novel dipeptide derived from porcine liver hydrolysate induces recovery from physical fatigue in a mouse model by Nakagawasai, Osamu, Yamada, Kotaro, Sakuma, Wakana, Takahashi, Kohei, Odaira, Takayo, Yamagata, Ryota, Nemoto, Wataru, Ejima, Akika, Sato, Kenji, Tan-No, Koichi

“…[Display omitted] •Hydrophobic peptides with an amino group in LH exerted anti-fatigue effects.•Asp-Leu (Lβ), Asp-Phe (Dα), and Asp-Phe (Lα) exerted…”
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Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice by Nemoto, Wataru, Yamada, Kotaro, Nakagawasai, Osamu, Ogata, Yoshiki, Chiba, Masato, Yamagata, Ryota, Sakurai, Hidetomo, Tan-No, Koichi

“…We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation…”
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Downregulation of spinal angiotensin converting enzyme 2 is involved in neuropathic pain associated with type 2 diabetes mellitus in mice by Yamagata, Ryota, Nemoto, Wataru, Nakagawasai, Osamu, Takahashi, Kohei, Tan-No, Koichi

“…[Display omitted] We have previously reported that the spinal angiotensin (Ang) system is involved in the modulation of streptozotocin (STZ)-induced diabetic…”
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Long-term effects of a single high-dose intraperitoneal injection of lipopolysaccharide on depression-like behavior in adolescent mice by Nakagawasai, Osamu, Takahashi, Kohei, Suzuki, Takuto, Yamagata, Ryota, Nemoto, Wataru, Tan-No, Koichi

“…The commonly used lipopolysaccharide (LPS)-induced depression models often evaluate depression-like behaviors in the acute phase after a single intraperitoneal…”
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Involvement of Spinal Angiotensin II System in Streptozotocin-Induced Diabetic Neuropathic Pain in Mice by Ogata, Yoshiki, Nemoto, Wataru, Nakagawasai, Osamu, Yamagata, Ryota, Tadano, Takeshi, Tan-No, Koichi

“…Renin-angiotensin system (RAS) activity increases under hyperglycemic states, and is thought to be involved in diabetic complications. We previously…”
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Dopamine D 2 receptor supersensitivity in the hypothalamus of olfactory bulbectomized mice by Takahashi, Kohei, Nakagawasai, Osamu, Nakajima, Takeharu, Okubo, Myu, Nishimura, Yuki, Sakuma, Wakana, Yamagata, Ryota, Nemoto, Wataru, Miyagawa, Kazuya, Kurokawa, Kazuhiro, Mochida-Saito, Atsumi, Tsuji, Minoru, Takeda, Hiroshi, Tadano, Takeshi, Tan-No, Koichi

“…Olfactory bulbectomy (OBX) in rodents induces neurochemical and behavioral changes similar to those observed in individuals with depressive disorders. Our…”
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Dopamine D2 receptor supersensitivity in the hypothalamus of olfactory bulbectomized mice by Takahashi, Kohei, Nakagawasai, Osamu, Nakajima, Takeharu, Okubo, Myu, Nishimura, Yuki, Sakuma, Wakana, Yamagata, Ryota, Nemoto, Wataru, Miyagawa, Kazuya, Kurokawa, Kazuhiro, Mochida-Saito, Atsumi, Tsuji, Minoru, Takeda, Hiroshi, Tadano, Takeshi, Tan-No, Koichi

“…•Sulpiride reversed apomorphine-induced hypothermic response in OBX mice.•SCH23390 and SB277011A failed to reverse apomorphine-induced hypothermia.•OBX mice…”
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Inhibitory effect of angiotensin (1-7) on angiotensin III-induced nociceptive behaviour in mice by Nemoto, Wataru, Yamagata, Ryota, Ogata, Yoshiki, Nakagawasai, Osamu, Tadano, Takeshi, Tan-No, Koichi

“…Abstract We have previously demonstrated that the intrathecal (i.t.) administration of angiotensin (Ang) II into mice produces a nociceptive behaviour…”
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Etidronate attenuates tactile allodynia by spinal ATP release inhibition in mice with partial sciatic nerve ligation by Yamagata, Ryota, Nemoto, Wataru, Nakagawasai, Osamu, Hung, Wan-Yi, Shima, Kazuhiro, Endo, Yasuo, Tan-No, Koichi

“…Etidronate is widely used as a therapeutic agent for osteoporosis. We have recently shown that intrathecal administration of etidronate into mice produces an…”
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