Search Results - "Yamaga, Yuichi"
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Lineage tracing and targeting of IL17RB⁺ tuft cell-like human colorectal cancer stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2019)“…Cancer stem cell (CSC)-specific markers may be potential therapeutic targets. We previously identified that Dclk1, a tuft cell marker, marks tumor stem cells…”
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Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
Published in eLife (04-01-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. Although rigorous efforts identified the presence of 'cancer stem cells (CSCs)' in PDAC and…”
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Bmi1 marks gastric stem cells located in the isthmus in mice
Published in The Journal of pathology (01-06-2019)“…In the mammalian stomach, the isthmus has been considered as a stem cell zone. However, various locations and proliferative activities of gastric stem cells…”
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The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis
Published in The Journal of clinical investigation (01-08-2018)“…Chromatin remodeler Brahma related gene 1 (BRG1) is silenced in approximately 10% of human pancreatic ductal adenocarcinomas (PDAs). We previously showed that…”
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Eosinophilic enteritis accompanied by cytomegalovirus disease: a case report
Published in BMC gastroenterology (28-04-2022)“…Eosinophilic enteritis is a chronic inflammatory disorder of the intestinal tract that is characterized by eosinophil infiltration. Cytomegalovirus (CMV), a…”
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A tumor stem cell-specific marker identified by lineage tracing in the intestine
Published in Nihon rinshō (01-05-2015)“…Tumor therapies targeting tumor stem cells(TSCs) have been limited. One of the reasons is that TSC markers are often shared by normal stem cells (NSCs), and…”
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Sinusoidal obstructive syndrome with hypereosinophilia successfully treated with prednisolone
Published in Clinical journal of gastroenterology (01-02-2012)“…A 60-year-old man was admitted to Tenri Hospital complaining of erythema and abdominal distention. There were marked liver damage and hypereosinophilia. The…”
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Dclk1 distinguishes between tumor and normal stem cells in the intestine
Published in Nature genetics (01-01-2013)“…Hiroshi Seno and colleagues report that Dclk1 selectively marks intestinal tumor stem cells. They further show that specific ablation of these cells in a mouse…”
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Su2002 Microarray Analysis of DCLK1-positive Intestinal Tumor Stem Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2015)Get full text
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Gene expression profile of Dclk1+ cells in intestinal tumors
Published in Digestive and liver disease (01-12-2018)“…Accumulating evidence has shown the existence of tumor stem cells with therapeutic potential. Previously, we reported that doublecortin like kinase 1 (Dclk1)…”
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Epithelial EP4 plays an essential role in maintaining homeostasis in colon
Published in Scientific reports (23-10-2019)“…Colonic epithelial cells comprise the mucosal barrier, and their dysfunction promotes microbial invasion from the gut lumen and induces the development of…”
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A case of jejunal adenocarcinoma with serum DUPAN-2 elevation
Published in Nippon Shōkakibyō Gakkai zasshi (01-11-2010)“…A 50-year-old woman was admitted to our hospital because of abdominal pain and vomiting. Ileus with ulcerated jejunal tumor was diagnosed and biopsy revealed…”
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