Search Results - "Yamada, Shizuka B."

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS by Jovičić, Ana, Mertens, Jerome, Boeynaems, Steven, Bogaert, Elke, Chai, Noori, Yamada, Shizuka B, Paul, Joseph W, Sun, Shuying, Herdy, Joseph R, Bieri, Gregor, Kramer, Nicholas J, Gage, Fred H, Van Den Bosch, Ludo, Robberecht, Wim, Gitler, Aaron D

“…C9orf72 mutations are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia. With unbiased screens in Saccharomyces cerevisiae ,…”
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RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats by Yamada, Shizuka B., Gendron, Tania F., Niccoli, Teresa, Genuth, Naomi R., Grosely, Rosslyn, Shi, Yingxiao, Glaria, Idoia, Kramer, Nicholas J., Nakayama, Lisa, Fang, Shirleen, Dinger, Tai J. I., Thoeng, Annora, Rocha, Gabriel, Barna, Maria, Puglisi, Joseph D., Partridge, Linda, Ichida, Justin K., Isaacs, Adrian M., Petrucelli, Leonard, Gitler, Aaron D.

“…Nucleotide repeat expansions in the C9orf72 gene are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia. Unconventional…”
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Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation by Coyne, Alyssa N, Yamada, Shizuka B, Siddegowda, Bhavani Bagevalu, Estes, Patricia S, Zaepfel, Benjamin L, Johannesmeyer, Jeffrey S, Lockwood, Donovan B, Pham, Linh T, Hart, Michael P, Cassel, Joel A, Freibaum, Brian, Boehringer, Ashley V, Taylor, J Paul, Reitz, Allen B, Gitler, Aaron D, Zarnescu, Daniela C

“…RNA dysregulation is a newly recognized disease mechanism in amyotrophic lateral sclerosis (ALS). Here we identify Drosophila fragile X mental retardation…”
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A memory of eS25 loss drives resistance phenotypes by Johnson, Alex G, Flynn, Ryan A, Lapointe, Christopher P, Ooi, Yaw Shin, Zhao, Michael L, Richards, Christopher M, Qiao, Wenjie, Yamada, Shizuka B, Couthouis, Julien, Gitler, Aaron D, Carette, Jan E, Puglisi, Joseph D

“…Abstract In order to maintain cellular protein homeostasis, ribosomes are safeguarded against dysregulation by myriad processes. Remarkably, many cell types…”
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Modifiers of C9orf72 DPR toxicity implicate nucleocytoplasmic transport impairments in c9FTD/ALS by Jovičić, Ana, Mertens, Jerome, Boeynaems, Steven, Bogaert, Elke, Chai, Noori, Yamada, Shizuka B., Paul, Joseph W., Sun, Shuying, Herdy, Joseph R., Bieri, Gregor, Kramer, Nicholas J., Gage, Fred H., Den Bosch, Ludo Van, Robberecht, Wim, Gitler, Aaron D.

“…C9orf72 mutations are the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Dipeptide repeat proteins (DPRs) produced…”
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